Molecular cloning of Aralar, a new member of the mitochondrial carrier superfamily that binds calcium and is present in human muscle and brain
about
Characterization of a second member of the subfamily of calcium-binding mitochondrial carriers expressed in human non-excitable tissuesCitrin and aralar1 are Ca(2+)-stimulated aspartate/glutamate transporters in mitochondriaRecombinant expression of the Ca(2+)-sensitive aspartate/glutamate carrier increases mitochondrial ATP production in agonist-stimulated Chinese hamster ovary cellsRole of the malate-aspartate shuttle on the metabolic response to myocardial ischemiaThe regulation of neuronal mitochondrial metabolism by calciumSCaMC-1Like a member of the mitochondrial carrier (MC) family preferentially expressed in testis and localized in mitochondria and chromatoid bodySal1p, a calcium-dependent carrier protein that suppresses an essential cellular function associated With the Aac2 isoform of ADP/ATP translocase in Saccharomyces cerevisiae.SLC25A23 augments mitochondrial Ca²⁺ uptake, interacts with MCU, and induces oxidative stress-mediated cell deathAutism: the quest for the genesSLC25A12 expression is associated with neurite outgrowth and is upregulated in the prefrontal cortex of autistic subjectsThe malate-aspartate NADH shuttle member Aralar1 determines glucose metabolic fate, mitochondrial activity, and insulin secretion in beta cellsPhysiological and pathological roles of mitochondrial SLC25 carriersSlc25a13-knockout mice harbor metabolic deficits but fail to display hallmarks of adult-onset type II citrullinemiaCa2+ Activation kinetics of the two aspartate-glutamate mitochondrial carriers, aralar and citrin: role in the heart malate-aspartate NADH shuttleAlternative splicing generates a novel non-secretable resistin isoform in Wistar ratsRegulation of the mitochondrial proton gradient by cytosolic Ca2+ signalsCalcium-induced conformational changes of the regulatory domain of human mitochondrial aspartate/glutamate carriers.Glutamate as a neurotransmitter in the healthy brainPhysical and functional interaction of NCX1 and EAAC1 transporters leading to glutamate-enhanced ATP production in brain mitochondriaATP synthesis and storage.Identification of a novel human subfamily of mitochondrial carriers with calcium-binding domains.Pyruvate kinase and aspartate-glutamate carrier distributions reveal key metabolic links between neurons and glia in retina.The role of Ca(2+) signaling in the coordination of mitochondrial ATP production with cardiac work.Association between genetic variants in SLC25A12 and risk of autism spectrum disorders: An integrated meta-analysis.Altered postnatal development of cortico-hippocampal neuronal electric activity in mice deficient for the mitochondrial aspartate-glutamate transporter.Aralar plays a significant role in maintaining the survival and mitochondrial membrane potential of BV2 microglia.Voxelwise gene-wide association study (vGeneWAS): multivariate gene-based association testing in 731 elderly subjectsl(2)01810 is a novel type of glutamate transporter that is responsible for megamitochondrial formation.Mitochondrial transporters as novel targets for intracellular calcium signaling.The molecular composition of the mitochondrial permeability transition pore.Deficient glucose and glutamine metabolism in Aralar/AGC1/Slc25a12 knockout mice contributes to altered visual functionPleiotropic effects of the yeast Sal1 and Aac2 carriers on mitochondrial function via an activity distinct from adenine nucleotide transport.The mitochondrial aspartate/glutamate carrier AGC1 and calcium homeostasis: physiological links and abnormalities in autism.Citrin/mitochondrial glycerol-3-phosphate dehydrogenase double knock-out mice recapitulate features of human citrin deficiency.Mitochondrial Aspartate/Glutamate Carrier SLC25A12 and Autism Spectrum Disorder: a Meta-Analysis.Quantitative proteome analysis of age-related changes in mouse gastrocnemius muscle using mTRAQ.Fluctuations in Cytosolic Calcium Regulate the Neuronal Malate-Aspartate NADH Shuttle: Implications for Neuronal Energy Metabolism.The mitochondrial aspartate/glutamate carrier isoform 1 gene expression is regulated by CREB in neuronal cells.Silencing of the mitochondrial NADH shuttle component aspartate-glutamate carrier AGC1/Aralar1 in INS-1E cells and rat islets.Overexpression of the malate-aspartate NADH shuttle member Aralar1 in the clonal beta-cell line BRIN-BD11 enhances amino-acid-stimulated insulin secretion and cell metabolism.
P2860
Q22011108-09EE4F26-C00C-4E94-9311-8C680ABF7DC8Q24291715-082453A0-22CB-4AC2-8AD8-3E1C9F7172F5Q24307541-964E7A62-E185-4698-83EA-8A1C4BD18369Q24648945-DCB341D9-245B-4362-BCCA-B8EB6978223EQ26823765-C3317989-01D5-4CFA-9551-F6726011049DQ27334859-4B067E1C-84ED-4764-99BE-D26EEF43E46BQ27929506-5B48CCC2-A20F-4EA7-BF76-562849973F62Q28118248-13F16214-50DD-4D29-AA49-40774508FB69Q28244222-8E93C579-CB46-47ED-B9D4-88AEC94DBA70Q28263933-ED298E7F-6E5D-4823-B1D1-FB37213D1F47Q28288682-66B530D8-EC0D-4BCC-BCEA-9C636964F6F7Q28297551-CCBDB489-E2D6-4DBC-A1CC-868E6CDDCBFFQ28506798-E14ED00F-18F0-47FA-9789-516C63129D57Q28512011-6D4F74BD-9AB9-41B0-B69A-1CBAC50DE1C0Q28572946-94DAA330-5A96-4F00-87C3-7785FC66CC2DQ29396514-A2A37C03-BB2C-4E13-BF36-D53CEDC928ECQ30604103-DEFB1A16-3BE6-4C15-A2E5-0D8A4917DE43Q34048502-28FE78D6-6D9A-4FE9-9EE8-D24BA5CD9A20Q34221922-668AACCF-5B3B-409C-B684-9BF31B633712Q34270492-D55C443A-3232-4D59-B53F-27BA722AA988Q34309836-4D445F1C-6472-4658-9283-C8D127E114C8Q34442074-D3B557DA-1127-44DF-98B1-41F499701511Q35225766-B7BE1EFB-33B2-47B9-92E5-81410BB3143AQ35617059-8A064C11-7691-4EB8-9811-3AD2634FF6E6Q35738304-A703474F-5D7C-4AC9-82DC-B3532FF828FFQ35997660-8B8065E2-7095-49B4-89FD-F9B3996A563FQ36006639-0A929BB7-4C17-4C90-97BD-EDB6B7B88059Q36287199-7C3AC78F-2587-4507-B862-B9F6842AC4FFQ36712743-2C511B02-7CAB-4D49-82C6-D84EB320B62DQ37195017-DF21F674-32A4-4C7D-8D8B-0FBAB447329FQ37337161-22D266A2-CE70-4121-BD80-09F30429DCACQ37359913-B861B083-590D-49C9-B96A-023CEE49238BQ37892408-430C699B-B8F0-4E38-8835-D3871FC3D87DQ38300554-8E734CFD-8ACD-418B-A5E8-3EBAFA9ACE47Q38348486-5929E67E-BCCF-4F88-82A2-274EC155201FQ38483307-7A3AD62C-CF13-4355-B06B-6985D5F37634Q38542199-F5A6A539-3612-413A-9ECE-C22230782884Q38918962-AFE8FD06-9801-4154-AACA-74487F1415BAQ39797821-981E4266-5268-47BA-82AC-8C6AA8EEC30BQ39864393-35B84C58-7630-4E29-9B81-DE7E0634BBC4
P2860
Molecular cloning of Aralar, a new member of the mitochondrial carrier superfamily that binds calcium and is present in human muscle and brain
description
1998 nî lūn-bûn
@nan
1998 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Molecular cloning of Aralar, a ...... sent in human muscle and brain
@ast
Molecular cloning of Aralar, a ...... sent in human muscle and brain
@en
Molecular cloning of Aralar, a ...... sent in human muscle and brain
@en-gb
Molecular cloning of Aralar, a ...... sent in human muscle and brain
@nl
type
label
Molecular cloning of Aralar, a ...... sent in human muscle and brain
@ast
Molecular cloning of Aralar, a ...... sent in human muscle and brain
@en
Molecular cloning of Aralar, a ...... sent in human muscle and brain
@en-gb
Molecular cloning of Aralar, a ...... sent in human muscle and brain
@nl
prefLabel
Molecular cloning of Aralar, a ...... sent in human muscle and brain
@ast
Molecular cloning of Aralar, a ...... sent in human muscle and brain
@en
Molecular cloning of Aralar, a ...... sent in human muscle and brain
@en-gb
Molecular cloning of Aralar, a ...... sent in human muscle and brain
@nl
P2860
P921
P356
P1476
Molecular cloning of Aralar, a ...... sent in human muscle and brain
@en
P2093
A del Arco
J Satrústegui
P2860
P304
23327-23334
P356
10.1074/JBC.273.36.23327
P407
P577
1998-09-01T00:00:00Z