Identification of BMP9 and BMP10 as functional activators of the orphan activin receptor-like kinase 1 (ALK1) in endothelial cells
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Tmem100, an ALK1 receptor signaling-dependent gene essential for arterial endothelium differentiation and vascular morphogenesisEndoglin mediates fibronectin/α5β1 integrin and TGF-β pathway crosstalk in endothelial cellsCritical role of endoglin in tumor cell plasticity of Ewing sarcoma and melanomaCasein kinase 2beta as a novel enhancer of activin-like receptor-1 signalingBone morphogenetic protein (BMP) and activin type II receptors balance BMP9 signals mediated by activin receptor-like kinase-1 in human pulmonary artery endothelial cellsALK1 signaling regulates early postnatal lymphatic vessel developmentBMP9 mutations cause a vascular-anomaly syndrome with phenotypic overlap with hereditary hemorrhagic telangiectasiaExpression of vascular endothelial growth factor is coordinately regulated by the activin-like kinase receptors 1 and 5 in endothelial cellsHereditary haemorrhagic telangiectasia: a clinical and scientific reviewAutocrine bone morphogenetic protein-9 signals through activin receptor-like kinase-2/Smad1/Smad4 to promote ovarian cancer cell proliferationChordin-like 1 and twisted gastrulation 1 regulate BMP signaling following kidney injuryBone morphogenetic protein-9 is a circulating vascular quiescence factorTargeting BMP signalling in cardiovascular disease and anaemiaRole of endoglin in fibrosis and sclerodermaOveractive bone morphogenetic protein signaling in heterotopic ossification and Duchenne muscular dystrophyPotential roles of BMP9 in liver fibrosisVascular anomalies: from genetics toward models for therapeutic trialsEndothelial expression of TGFβ type II receptor is required to maintain vascular integrity during postnatal development of the central nervous systemSpecificity and Structure of a High Affinity Activin Receptor-like Kinase 1 (ALK1) Signaling ComplexFunctional and splicing defect analysis of 23 ACVRL1 mutations in a cohort of patients affected by Hereditary Hemorrhagic TelangiectasiaBMP9 is a proliferative and survival factor for human hepatocellular carcinoma cellsDesigner TGFβ superfamily ligands with diversified functionalityEnhanced responses to angiogenic cues underlie the pathogenesis of hereditary hemorrhagic telangiectasia 2Endoglin haploinsufficiency promotes fibroblast accumulation during wound healing through Akt activationMutations in GDF5 reveal a key residue mediating BMP inhibition by NOGGINALK5- and TGFBR2-independent role of ALK1 in the pathogenesis of hereditary hemorrhagic telangiectasia type 2Inactivation of Smad5 in endothelial cells and smooth muscle cells demonstrates that Smad5 is required for cardiac homeostasisInteraction between alk1 and blood flow in the development of arteriovenous malformationsGenome-wide RNAi screen reveals ALK1 mediates LDL uptake and transcytosis in endothelial cells.BMP-9 induced endothelial cell tubule formation and inhibition of migration involves Smad1 driven endothelin-1 production.Endoglin-mediated suppression of prostate cancer invasion is regulated by activin and bone morphogenetic protein type II receptors.An in vivo reporter of BMP signaling in organogenesis reveals targets in the developing kidney.Endoglin and activin receptor-like-kinase 1 are co-expressed in the distal vessels of the lung: implications for two familial vascular dysplasias, HHT and PAH.A rapid and sensitive bioassay for the simultaneous measurement of multiple bone morphogenetic proteins. Identification and quantification of BMP4, BMP6 and BMP9 in bovine and human serum.A phase I study of the human anti-activin receptor-like kinase 1 antibody PF-03446962 in Asian patients with advanced solid tumorsActRIIA and BMPRII Type II BMP receptor subunits selectively required for Smad4-independent BMP7-evoked chemotaxisELLIPSE Study: a Phase 1 study evaluating the tolerance of bevacizumab nasal spray in the treatment of epistaxis in hereditary hemorrhagic telangiectasiaBMP-2/6 heterodimer is more effective than BMP-2 or BMP-6 homodimers as inductor of differentiation of human embryonic stem cellsCharacterization of the human Activin-A receptor type II-like kinase 1 (ACVRL1) promoter and its regulation by Sp1Activin A more prominently regulates muscle mass in primates than does GDF8.
P2860
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P248
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P2860
Identification of BMP9 and BMP10 as functional activators of the orphan activin receptor-like kinase 1 (ALK1) in endothelial cells
description
2007 nî lūn-bûn
@nan
2007 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի մարտին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Identification of BMP9 and BMP ...... 1 (ALK1) in endothelial cells
@ast
Identification of BMP9 and BMP ...... 1 (ALK1) in endothelial cells
@en
Identification of BMP9 and BMP ...... 1 (ALK1) in endothelial cells
@en-gb
Identification of BMP9 and BMP ...... 1 (ALK1) in endothelial cells
@nl
type
label
Identification of BMP9 and BMP ...... 1 (ALK1) in endothelial cells
@ast
Identification of BMP9 and BMP ...... 1 (ALK1) in endothelial cells
@en
Identification of BMP9 and BMP ...... 1 (ALK1) in endothelial cells
@en-gb
Identification of BMP9 and BMP ...... 1 (ALK1) in endothelial cells
@nl
prefLabel
Identification of BMP9 and BMP ...... 1 (ALK1) in endothelial cells
@ast
Identification of BMP9 and BMP ...... 1 (ALK1) in endothelial cells
@en
Identification of BMP9 and BMP ...... 1 (ALK1) in endothelial cells
@en-gb
Identification of BMP9 and BMP ...... 1 (ALK1) in endothelial cells
@nl
P2093
P921
P3181
P1433
P1476
Identification of BMP9 and BMP ...... 1 (ALK1) in endothelial cells
@en
P2093
Christine Mallet
Sabine Bailly
Sabine Mazerbourg
P304
P3181
P356
10.1182/BLOOD-2006-07-034124
P407
P577
2007-03-01T00:00:00Z