Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization
about
Iron, hepcidin, and the metal connectionRetinal iron homeostasis in health and diseaseShared and distinct mechanisms of iron acquisition by bacterial and fungal pathogens of humansPro-protein convertases control the maturation and processing of the iron-regulatory protein, RGMc/hemojuvelinAlcoholic liver disease and hepatitis C: a frequently underestimated combinationInterleukin-6 induces hepcidin expression through STAT3HFE interacts with the BMP type I receptor ALK3 to regulate hepcidin expressionHuman ESCRT-II complex and its role in human immunodeficiency virus type 1 releaseInhibition of iron uptake by ferristatin II is exerted through internalization of DMT1 at the plasma membraneHemojuvelin is essential for dietary iron sensing, and its mutation leads to severe iron overloadBone morphogenetic protein signaling by hemojuvelin regulates hepcidin expressionCD81 promotes both the degradation of transferrin receptor 2 (TfR2) and the Tfr2-mediated maintenance of hepcidin expressionA time course of hepcidin response to iron challenge in patients with HFE and TFR2 hemochromatosisHemojuvelin regulates hepcidin expression via a selective subset of BMP ligands and receptors independently of neogeninHepcidin-induced endocytosis of ferroportin is dependent on ferroportin ubiquitinationKinetics and specificity of feline leukemia virus subgroup C receptor (FLVCR) export function and its dependence on hemopexinA mouse model of juvenile hemochromatosis.Hepcidin--the iron regulatory hormone.Tissue-specific expression of ferritin H regulates cellular iron homoeostasis in vivoConserved proximal promoter elements control repulsive guidance molecule c/hemojuvelin (Hfe2) gene transcription in skeletal muscleIneffective erythropoiesis and thalassemiasHepcidin mediates transcriptional changes that modulate acute cytokine-induced inflammatory responses in miceThe liver-specific microRNA miR-122 controls systemic iron homeostasis in miceER stress controls iron metabolism through induction of hepcidinErythropoietin administration in humans causes a marked and prolonged reduction in circulating hepcidinHepcidin as a therapeutic tool to limit iron overload and improve anemia in β-thalassemic miceHereditary hemochromatosis in the post-HFE eraMolecular basis of inherited microcytic anemia due to defects in iron acquisition or heme synthesisThe human side of hypoxia-inducible factorPosttranslational processing of hepcidin in human hepatocytes is mediated by the prohormone convertase furinFerroportin is a manganese-responsive protein that decreases manganese cytotoxicity and accumulationHepcidin revisited, disulfide connectivity, dynamics, and structureCurcumin, a cancer chemopreventive and chemotherapeutic agent, is a biologically active iron chelatorPathophysiology of hereditary hemochromatosisThe flatiron mutation in mouse ferroportin acts as a dominant negative to cause ferroportin diseaseModulation of bone morphogenetic protein signaling in vivo regulates systemic iron balanceSLC40A1 Q248H allele frequencies and Q248H-associated risk of non-HFE iron overload in persons of sub-Saharan African descentIron Fortification of Foods for Infants and Children in Low-Income Countries: Effects on the Gut Microbiome, Gut Inflammation, and DiarrheaThe pathophysiology of thrombocytopenia in chronic liver diseaseDiet and risk of breast cancer
P2860
01cc7acfe63243a84d7d07fdc215cea3b23ca1464ee85954693c226d88d68f462fba21854f1566bd6b5d4fd91d301c242e6693d7c1b5af9da14558107230c3eff1d9a911d1b671b84d2f3c0df325d465899701db8dc4d1ef92ac06bb515deb8fa8b42f2a9c9f9f9db9c1b9ebb668cf1c5dd1eb2eb1e8d70d9e820d84cec2d6aa6329eb1356e5ecf55345e55dc44488a558eabf1171e6432fdcbef88f745f6b4ceb450a064886946ab9bb25e01e24c8218455e638
P248
Q21129273-01F3704A-2951-48D2-9AC1-4CE9EDC37C73Q21131069-B327AABF-1F18-44FF-90F5-5635051F75ADQ21131297-9E0B1661-D070-4566-9212-123AE18F3E23Q21284382-296B636C-4F93-4CC3-B5A8-E1F10D4D02EFQ22305502-2832E3A5-F3D1-4755-9243-8337DC397503Q24296906-6A5E1E2A-5462-4837-9BA7-ACC00993BE02Q24298843-906E4C0A-4AE9-4E20-A6FD-7168D43BA37BQ24303183-66B673D6-26C6-468E-A805-6811AD798319Q24308927-060AC83F-C5FB-4436-8BC7-55974DFB08FCQ24312272-6B490752-85AC-4DD6-8D65-1EE6AF965665Q24316099-82FF3451-9715-494D-9F21-0762462E74DFQ24317017-8231D5C1-06E7-4C50-BDC8-AF9782F6EA0DQ24318821-2D599E56-DABB-489C-A7BC-F5D009EC059DQ24321923-A12A7384-6676-4BC1-B04C-E40B2F6FF316Q24337699-68E3B3D5-C8EA-4C94-9B6E-9E2C2CF0A762Q24338112-B2C7E730-D54C-4A4C-B32D-D5AE06075450Q24532268-148C33D5-734F-441D-B162-1C90897179E5Q24536439-0394AC97-3AA1-414E-BF50-2B7D927C7588Q24543925-EDD39BF9-43BD-4AA2-84A0-B6A2EC27C756Q24569886-79D6608F-62EB-49CC-8898-A295170D52ACQ24602905-79DCCC40-CAED-4500-9658-45461CEE2C0CQ24617847-266F7533-F7E1-4DA7-BC6E-014595F55F21Q24628683-01CDB078-B0C8-4EA4-8D6C-D2B2B485AF3EQ24630714-CFF03268-775B-4C85-B4B6-DD074C4CE6D8Q24632978-8DFAF50F-E84C-47AD-8C46-E9AF7ED40A3FQ24633423-1EFC56ED-95C8-4D7E-8502-677769C1350DQ24646056-20BD322F-803D-4399-945F-588E12CCF451Q24646911-010DE636-B13E-45F6-AF33-8D2F6F85CF09Q24646951-6BA5CB33-8B25-4B81-9B4E-7FE81F394CB4Q24648028-29B731F6-AEBC-4EA4-8637-585BB83C7747Q24650332-79E07252-0DA5-4F09-9067-E8E5B5717C18Q24651444-51383A38-9A40-422A-B21F-9788D4CA4688Q24652363-736F05C8-5465-473D-9384-FEE021E3D17AQ24654441-6D970B61-AB8A-4648-AEF0-F13620819FA4Q24678328-BDAF500F-4202-4A80-9541-EE2D3C0CCA3EQ24682390-2E7A3D28-3586-458E-8B31-E1D90E4DE363Q24682642-F1B0F36B-8F71-4FDA-AA56-644E43FEC098Q26741173-C870DA64-2F4A-4288-BCD1-97AB10C708F5Q26749277-E7A99346-E563-4F7B-B1EA-625E7CBA0F4BQ26751985-75628ABE-554A-4292-9491-F8B740586740
P2860
Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization
description
2004 nî lūn-bûn
@nan
2004 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Hepcidin regulates cellular ir ...... d inducing its internalization
@ast
Hepcidin regulates cellular ir ...... d inducing its internalization
@en
Hepcidin regulates cellular ir ...... d inducing its internalization
@en-gb
Hepcidin regulates cellular ir ...... d inducing its internalization
@nl
type
label
Hepcidin regulates cellular ir ...... d inducing its internalization
@ast
Hepcidin regulates cellular ir ...... d inducing its internalization
@en
Hepcidin regulates cellular ir ...... d inducing its internalization
@en-gb
Hepcidin regulates cellular ir ...... d inducing its internalization
@nl
prefLabel
Hepcidin regulates cellular ir ...... d inducing its internalization
@ast
Hepcidin regulates cellular ir ...... d inducing its internalization
@en
Hepcidin regulates cellular ir ...... d inducing its internalization
@en-gb
Hepcidin regulates cellular ir ...... d inducing its internalization
@nl
P2093
P921
P3181
P356
P1433
P1476
Hepcidin regulates cellular ir ...... d inducing its internalization
@en
P2093
Adriana Donovan
Diane McVey Ward
Elizabeta Nemeth
Jerry Kaplan
Julie Powelson
Michael B Vaughn
P304
P3181
P356
10.1126/SCIENCE.1104742
P407
P577
2004-12-17T00:00:00Z