PTPH1 cooperates with vitamin D receptor to stimulate breast cancer growth through their mutual stabilization
about
Vitamin D and the RNA transcriptome: more than mRNA regulation.The vitamin D receptor is involved in the regulation of human breast cancer cell growth via a ligand-independent function in cytoplasmhsa-mir-30c promotes the invasive phenotype of metastatic breast cancer cells by targeting NOV/CCN3.Epidermal growth factor receptor (EGFR)-mediated positive feedback of protein-tyrosine phosphatase epsilon (PTPepsilon) on ERK1/2 and AKT protein pathways is required for survival of human breast cancer cells.p38γ mitogen-activated protein kinase (MAPK) confers breast cancer hormone sensitivity by switching estrogen receptor (ER) signaling from classical to nonclassical pathway via stimulating ER phosphorylation and c-Jun transcription.Tyrosine dephosphorylation enhances the therapeutic target activity of epidermal growth factor receptor (EGFR) by disrupting its interaction with estrogen receptor (ER).p38γ Mitogen-activated protein kinase signals through phosphorylating its phosphatase PTPH1 in regulating ras protein oncogenesis and stress response.p38γ MAPK Is a Therapeutic Target for Triple-Negative Breast Cancer by Stimulation of Cancer Stem-Like Cell Expansion.Protein tyrosine phosphatase PTPN3 promotes drug resistance and stem cell-like characteristics in ovarian cancerPDZ domains: the building blocks regulating tumorigenesis.Protein tyrosine phosphatase PTPN3 inhibits lung cancer cell proliferation and migration by promoting EGFR endocytic degradation.Unfavorable effect of calcitriol and its low-calcemic analogs on metastasis of 4T1 mouse mammary gland cancer.The K-Ras effector p38γ MAPK confers intrinsic resistance to tyrosine kinase inhibitors by stimulating EGFR transcription and EGFR dephosphorylation.
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PTPH1 cooperates with vitamin D receptor to stimulate breast cancer growth through their mutual stabilization
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2011 nî lūn-bûn
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2011 թուականի Ապրիլին հրատարակուած գիտական յօդուած
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2011 թվականի ապրիլին հրատարակված գիտական հոդված
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2011年の論文
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2011年論文
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2011年論文
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2011年論文
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2011年論文
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2011年論文
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2011年论文
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PTPH1 cooperates with vitamin ...... ugh their mutual stabilization
@ast
PTPH1 cooperates with vitamin ...... ugh their mutual stabilization
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PTPH1 cooperates with vitamin ...... ugh their mutual stabilization
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PTPH1 cooperates with vitamin ...... ugh their mutual stabilization
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PTPH1 cooperates with vitamin ...... ugh their mutual stabilization
@ast
PTPH1 cooperates with vitamin ...... ugh their mutual stabilization
@en
PTPH1 cooperates with vitamin ...... ugh their mutual stabilization
@en-gb
PTPH1 cooperates with vitamin ...... ugh their mutual stabilization
@nl
prefLabel
PTPH1 cooperates with vitamin ...... ugh their mutual stabilization
@ast
PTPH1 cooperates with vitamin ...... ugh their mutual stabilization
@en
PTPH1 cooperates with vitamin ...... ugh their mutual stabilization
@en-gb
PTPH1 cooperates with vitamin ...... ugh their mutual stabilization
@nl
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PTPH1 cooperates with vitamin ...... ugh their mutual stabilization
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10.1038/ONC.2010.543
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2011-04-07T00:00:00Z
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1045928064