The human trithorax protein hASH2 functions as an oncoprotein
about
The Trithorax group protein Ash2l and Saf-A are recruited to the inactive X chromosome at the onset of stable X inactivationAsh2l interacts with Tbx1 and is required during early embryogenesisWDR5 Expression Is Prognostic of Breast Cancer Outcome.Dumpy-30 family members as determinants of male fertility and interaction partners of metal-responsive transcription factor 1 (MTF-1) in Drosophila.Discovering cancer genes by integrating network and functional properties.A conserved interaction between the SDI domain of Bre2 and the Dpy-30 domain of Sdc1 is required for histone methylation and gene expression.TRAUCO, a Trithorax-group gene homologue, is required for early embryogenesis in Arabidopsis thaliana.Rbm15-Mkl1 interacts with the Setd1b histone H3-Lys4 methyltransferase via a SPOC domain that is required for cytokine-independent proliferation.Drosophila Myc interacts with host cell factor (dHCF) to activate transcription and control growthAbsent, small or homeotic 2-like protein (ASH2L) enhances the transcription of the estrogen receptor α gene through GATA-binding protein 3 (GATA3).A novel non-SET domain multi-subunit methyltransferase required for sequential nucleosomal histone H3 methylation by the mixed lineage leukemia protein-1 (MLL1) core complexProtein-arginine methyltransferase 1 (PRMT1) methylates Ash2L, a shared component of mammalian histone H3K4 methyltransferase complexes.Transforming properties of 8p11-12 amplified genes in human breast cancer.ING5 is phosphorylated by CDK2 and controls cell proliferation independently of p53Roles of DPY30 in the Proliferation and Motility of Gastric Cancer Cells.A Tox21 Approach to Altered Epigenetic Landscapes: Assessing Epigenetic Toxicity Pathways Leading to Altered Gene Expression and Oncogenic Transformation In VitroModifying metabolically sensitive histone marks by inhibiting glutamine metabolism affects gene expression and alters cancer cell phenotype.Dpy30 is critical for maintaining the identity and function of adult hematopoietic stem cellsGenome recognition by MYC.Epigenetic silencing and activation of transcription: influence on the radiation sensitivity of glioma cell lines.Role of UTX in retinoic acid receptor-mediated gene regulation in leukemia.A SET-domain-independent role of WRAD complex in cell-cycle regulatory function of mixed lineage leukemia.The interaction of MYC with the trithorax protein ASH2L promotes gene transcription by regulating H3K27 modification.PHF8 targets histone methylation and RNA polymerase II to activate transcription.S-adenosyl homocysteine hydrolase is required for Myc-induced mRNA cap methylation, protein synthesis, and cell proliferation.Low expression of ASH2L protein correlates with a favorable outcome in acute myeloid leukemia.Modes of Interaction of KMT2 Histone H3 Lysine 4 Methyltransferase/COMPASS Complexes with Chromatin.Hijacking a key chromatin modulator creates epigenetic vulnerability for MYC-driven cancer
P2860
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P2860
The human trithorax protein hASH2 functions as an oncoprotein
description
2008 nî lūn-bûn
@nan
2008 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
The human trithorax protein hASH2 functions as an oncoprotein
@ast
The human trithorax protein hASH2 functions as an oncoprotein
@en
The human trithorax protein hASH2 functions as an oncoprotein
@en-gb
The human trithorax protein hASH2 functions as an oncoprotein
@nl
type
label
The human trithorax protein hASH2 functions as an oncoprotein
@ast
The human trithorax protein hASH2 functions as an oncoprotein
@en
The human trithorax protein hASH2 functions as an oncoprotein
@en-gb
The human trithorax protein hASH2 functions as an oncoprotein
@nl
prefLabel
The human trithorax protein hASH2 functions as an oncoprotein
@ast
The human trithorax protein hASH2 functions as an oncoprotein
@en
The human trithorax protein hASH2 functions as an oncoprotein
@en-gb
The human trithorax protein hASH2 functions as an oncoprotein
@nl
P2093
P50
P1433
P1476
The human trithorax protein hASH2 functions as an oncoprotein
@en
P2093
Axel Wellmann
Bernhard Lüscher
Chantal Rodgarkia-Schamberger
Gesa Walsemann
Henning Schuchlautz
Isabella Gawlista
Karsten Kapelle
Stephan Dreschers
Till Braunschweig
P304
P356
10.1158/0008-5472.CAN-07-3158
P407
P577
2008-02-01T00:00:00Z