Dimerization properties of human BAD. Identification of a BH-3 domain and analysis of its binding to mutant BCL-2 and BCL-XL proteins
about
Vapor of volatile oils from Litsea cubeba seed induces apoptosis and causes cell cycle arrest in lung cancer cellsBoo, a novel negative regulator of cell death, interacts with Apaf-1.tBID, a membrane-targeted death ligand, oligomerizes BAK to release cytochrome cBcl-G, a novel pro-apoptotic member of the Bcl-2 familyProtein phosphatase 1alpha is a Ras-activated Bad phosphatase that regulates interleukin-2 deprivation-induced apoptosisRationale for Bcl-xL/Bad peptide complex formation from structure, mutagenesis, and biophysical studiesSolution structure of the antiapoptotic protein bcl-2Solution structure of a Bcl-2 homolog from Kaposi sarcoma virus.Bcl-XL mutations suppress cellular sensitivity to antimycin AStructure of M11L: A myxoma virus structural homolog of the apoptosis inhibitor, Bcl-2The proapoptotic BH3-only protein BAD transduces cell death signals independently of its interaction with Bcl-2Temporal profiles of the subcellular localization of Bim, a BH3-only protein, during middle cerebral artery occlusion in miceA splicing variant of the Bcl-2 member Bok with a truncated BH3 domain induces apoptosis but does not dimerize with antiapoptotic Bcl-2 proteins in vitroTransforming growth factor beta 1 induces apoptosis through cleavage of BAD in a Smad3-dependent mechanism in FaO hepatoma cellsp70S6 kinase signals cell survival as well as growth, inactivating the pro-apoptotic molecule BADMolecular regulation of auditory hair cell death and approaches to protect sensory receptor cells and/or stimulate repair following acoustic trauma.Recent advances in the development of anticancer agents targeting cell death inhibitors in the Bcl-2 protein family.Interdependence of Bad and Puma during ionizing-radiation-induced apoptosis.Emerging Bcl-2 inhibitors for the treatment of cancer.BCL-2 is phosphorylated and inactivated by an ASK1/Jun N-terminal protein kinase pathway normally activated at G(2)/M.Death and survival signals determine active/inactive conformations of pro-apoptotic BAX, BAD, and BID molecules.Bcl-2 family proteins as targets for anticancer drug design.Correlations between gene expression and mercury levels in blood of boys with and without autism.Gene expressions in Jurkat cells poisoned by a sulphur mustard vesicant and the induction of apoptosisViral versus cellular BCL-2 proteins.Rapamycin induces Bad phosphorylation in association with its resistance to human lung cancer cells.Overexpression of Bcl-2-associated death inhibits A549 cell growth in vitro and in vivo.Estradiol abrogates apoptosis in breast cancer cells through inactivation of BAD: Ras-dependent nongenomic pathways requiring signaling through ERK and AktTargeting antiapoptotic Bcl-2 family members with cell-permeable BH3 peptides induces apoptosis signaling and death in head and neck squamous cell carcinoma cells.Bad can act as a key regulator of T cell apoptosis and T cell development.BCL2 family of apoptosis-related genes: functions and clinical implications in cancer.Dissociation of cytokine-induced phosphorylation of Bad and activation of PKB/akt: involvement of MEK upstream of Bad phosphorylation.BAD: undertaker by night, candyman by day.Therapeutic peptides for cancer therapy. Part II - cell cycle inhibitory peptides and apoptosis-inducing peptides.The mystery of BCL2 family: Bcl-2 proteins and apoptosis: an update.Caspase cleavage enhances the apoptosis-inducing effects of BAD.Arsenic trioxide (ATO) and MEK1 inhibition synergize to induce apoptosis in acute promyelocytic leukemia cells.Inhibition of phosphatidylinositol 3-kinase dephosphorylates BAD and promotes apoptosis in myeloid leukemias.Growth factors inactivate the cell death promoter BAD by phosphorylation of its BH3 domain on Ser155.Serine threonine kinase Pim-3 regulates STAT3 pathway to inhibit proliferation of human liver cancers.
P2860
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P2860
Dimerization properties of human BAD. Identification of a BH-3 domain and analysis of its binding to mutant BCL-2 and BCL-XL proteins
description
1997 nî lūn-bûn
@nan
1997 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1997年の論文
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1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Dimerization properties of hum ...... tant BCL-2 and BCL-XL proteins
@ast
Dimerization properties of hum ...... tant BCL-2 and BCL-XL proteins
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Dimerization properties of hum ...... tant BCL-2 and BCL-XL proteins
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Dimerization properties of hum ...... tant BCL-2 and BCL-XL proteins
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type
label
Dimerization properties of hum ...... tant BCL-2 and BCL-XL proteins
@ast
Dimerization properties of hum ...... tant BCL-2 and BCL-XL proteins
@en
Dimerization properties of hum ...... tant BCL-2 and BCL-XL proteins
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Dimerization properties of hum ...... tant BCL-2 and BCL-XL proteins
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prefLabel
Dimerization properties of hum ...... tant BCL-2 and BCL-XL proteins
@ast
Dimerization properties of hum ...... tant BCL-2 and BCL-XL proteins
@en
Dimerization properties of hum ...... tant BCL-2 and BCL-XL proteins
@en-gb
Dimerization properties of hum ...... tant BCL-2 and BCL-XL proteins
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P2093
P2860
P921
P356
P1476
Dimerization properties of hum ...... tant BCL-2 and BCL-XL proteins
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P2093
T Oltersdorf
P2860
P304
P356
10.1074/JBC.272.49.30866
P407
P577
1997-12-05T00:00:00Z