K63-specific deubiquitination by two JAMM/MPN+ complexes: BRISC-associated Brcc36 and proteasomal Poh1 - Test2 - elhamkhani - TriplyDB

K63-specific deubiquitination by two JAMM/MPN+ complexes: BRISC-associated Brcc36 and proteasomal Poh1

K63-specific deubiquitination by two JAMM/MPN+ complexes: BRISC-associated Brcc36 and proteasomal Poh1

http://www.wikidata.org/entity/Q24310641

about

The proteasomal de-ubiquitinating enzyme POH1 promotes the double-strand DNA break response OTU deubiquitinases reveal mechanisms of linkage specificity and enable ubiquitin chain restriction analysis Domain analysis reveals that a deubiquitinating enzyme USP13 performs non-activating catalysis for Lys63-linked polyubiquitin ATM-dependent chromatin changes silence transcription in cis to DNA double-strand breaks The Prp19 complex and the Usp4Sart3 deubiquitinating enzyme control reversible ubiquitination at the spliceosome Why do cellular proteins linked to K63-polyubiquitin chains not associate with proteasomes?The recognition of ubiquitinated proteins by the proteasome Substrate specificity of the ubiquitin and Ubl proteases Role of Deubiquitinating Enzymes in DNA Repair Fine-tuning the ubiquitin code at DNA double-strand breaks: deubiquitinating enzymes at work The deubiquitinating enzyme complex BRISC is required for proper mitotic spindle assembly in mammalian cells Engineered diubiquitin synthesis reveals Lys29-isopeptide specificity of an OTU deubiquitinase A Strategy for Modulation of Enzymes in the Ubiquitin System An ankyrin-repeat ubiquitin-binding domain determines TRABID's specificity for atypical ubiquitin chains Structure of the Rpn11-Rpn8 dimer reveals mechanisms of substrate deubiquitination during proteasomal degradation Disassembly of Lys11 and mixed linkage polyubiquitin conjugates provides insights into function of proteasomal deubiquitinases Rpn11 and Ubp6.A perturbed ubiquitin landscape distinguishes between ubiquitin in trafficking and in proteolysis.Regulation of Abro1/KIAA0157 during myocardial infarction and cell death reveals a novel cardioprotective mechanism for Lys63-specific deubiquitination A BRISC-SHMT complex deubiquitinates IFNAR1 and regulates interferon responses Proteasomes activate aggresome disassembly and clearance by producing unanchored ubiquitin chains Homologs of breast cancer genes in plants MERIT40 deficiency expands hematopoietic stem cell pools by regulating thrombopoietin receptor signaling The minimal deneddylase core of the COP9 signalosome excludes the Csn6 MPN- domain Recent advances in the research for the homolog of breast cancer associated gene AtROW1 in higher plants.A data set of human endogenous protein ubiquitination sites.Ubiquitin-Proteasome-Collagen (CUP) Pathway in Preterm Premature Rupture of Fetal Membranes.Specificity of the BRISC deubiquitinating enzyme is not due to selective binding to Lys63-linked polyubiquitin.Chemoenzymatic synthesis of bifunctional polyubiquitin substrates for monitoring ubiquitin chain remodeling.Toward an integrated structural model of the 26S proteasome Differential regulation of JAMM domain deubiquitinating enzyme activity within the RAP80 complex.The Lys63-specific deubiquitinating enzyme BRCC36 is regulated by two scaffold proteins localizing in different subcellular compartments ABRO1 suppresses tumourigenesis and regulates the DNA damage response by stabilizing p53.BRCC36A is epistatic to BRCA1 in DNA crosslink repair and homologous recombination in Arabidopsis thaliana The role of deubiquitinating enzymes in chromatin regulation.NBA1/MERIT40 and BRE interaction is required for the integrity of two distinct deubiquitinating enzyme BRCC36-containing complexes Versatile roles of k63-linked ubiquitin chains in trafficking.Downregulation of BRCA1-BRCA2-containing complex subunit 3 sensitizes glioma cells to temozolomide The BRCA1-RAP80 complex regulates DNA repair mechanism utilization by restricting end resection.Silencing BRE expression in human umbilical cord perivascular (HUCPV) progenitor cells accelerates osteogenic and chondrogenic differentiation.Trimming of ubiquitin chains by proteasome-associated deubiquitinating enzymes.

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P2860

K63-specific deubiquitination by two JAMM/MPN+ complexes: BRISC-associated Brcc36 and proteasomal Poh1

http://www.wikidata.org/entity/Q24310641

description

2009 nî lūn-bûn

@nan

2009 թուականի Մարտին հրատարակուած գիտական յօդուած

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2009 թվականի մարտին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年论文

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name

K63-specific deubiquitination ...... ed Brcc36 and proteasomal Poh1

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K63-specific deubiquitination ...... ed Brcc36 and proteasomal Poh1

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K63-specific deubiquitination ...... ed Brcc36 and proteasomal Poh1

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K63-specific deubiquitination ...... ed Brcc36 and proteasomal Poh1

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type

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K63-specific deubiquitination ...... ed Brcc36 and proteasomal Poh1

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K63-specific deubiquitination ...... ed Brcc36 and proteasomal Poh1

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K63-specific deubiquitination ...... ed Brcc36 and proteasomal Poh1

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K63-specific deubiquitination ...... ed Brcc36 and proteasomal Poh1

@nl

prefLabel

K63-specific deubiquitination ...... ed Brcc36 and proteasomal Poh1

@ast

K63-specific deubiquitination ...... ed Brcc36 and proteasomal Poh1

@en

K63-specific deubiquitination ...... ed Brcc36 and proteasomal Poh1

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K63-specific deubiquitination ...... ed Brcc36 and proteasomal Poh1

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K63-specific deubiquitination ...... ed Brcc36 and proteasomal Poh1

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Cecile M Pickart

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Colleen Cutcliffe

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Eric M Cooper

http://www.w3.org/2001/XMLSchema#string

Robert E Cohen

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Troels Z Kristiansen

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P2860

JAMM: a metalloprotease-like zinc site in the proteasome and signalosome

A HECT domain E3 enzyme assembles novel polyubiquitin chains

RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteins

RNF8 transduces the DNA-damage signal via histone ubiquitylation and checkpoint protein assembly

Regulation of BRCC, a holoenzyme complex containing BRCA1 and BRCA2, by a signalosome-like subunit and its role in DNA repair

A unique E1-E2 interaction required for optimal conjugation of the ubiquitin-like protein NEDD8

Abraxas and RAP80 form a BRCA1 protein complex required for the DNA damage response

RAP80 targets BRCA1 to specific ubiquitin structures at DNA damage sites

The zinc finger of the CSN-associated deubiquitinating enzyme USP15 is essential to rescue the E3 ligase Rbx1

The structure of the CYLD USP domain explains its specificity for Lys63-linked polyubiquitin and reveals a B box module

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621-31

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scholarly article

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2839512

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10.1038/EMBOJ.2009.27

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P407

P433

6

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28

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Akhilesh Pandey

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2009-03-18T00:00:00Z

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24005220

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P698

19214193

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P921

protein K63-linked deubiquitination

histone H2A K63-linked deubiquitination

BRCA1/BRCA2-containing complex subunit 3

Proteasome 26S subunit, non-ATPase 14

COP9 signalosome subunit 5

Abraxas 2, BRISC complex subunit

BRISC and BRCA1 A complex member 1

BRISC and BRCA1 A complex member 2

P932

2666030

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