RhoG activates Rac1 by direct interaction with the Dock180-binding protein Elmo
about
Ephexin4 and EphA2 mediate cell migration through a RhoG-dependent mechanismPH domain of ELMO functions in trans to regulate Rac activation via Dock180Identification of splicing variants of Rapostlin, a novel RND2 effector that interacts with neural Wiskott-Aldrich syndrome protein and induces neurite branchingAn alpha-helical extension of the ELMO1 pleckstrin homology domain mediates direct interaction to DOCK180 and is critical in Rac signalingKank attenuates actin remodeling by preventing interaction between IRSp53 and Rac1A novel and evolutionarily conserved PtdIns(3,4,5)P3-binding domain is necessary for DOCK180 signalling.Involvement of the Rho/Rac family member RhoG in caveolar endocytosisSGEF, a RhoG guanine nucleotide exchange factor that stimulates macropinocytosis.Dock3 induces axonal outgrowth by stimulating membrane recruitment of the WAVE complexELMO1 and Dock180, a bipartite Rac1 guanine nucleotide exchange factor, promote human glioma cell invasion.GEF what? Dock180 and related proteins help Rac to polarize cells in new waysParallel phosphatidylinositol 3-kinase (PI3K)-dependent and Src-dependent pathways lead to CXCL8-mediated Rac2 activation and chemotaxisErbB2 directly activates the exchange factor Dock7 to promote Schwann cell migration.Endogenous RhoG is dispensable for integrin-mediated cell spreading but contributes to Rac-independent migration.The DHR1 domain of DOCK180 binds to SNX5 and regulates cation-independent mannose 6-phosphate receptor transportFunction of the N-terminus of zizimin1: autoinhibition and membrane targeting.The CDM superfamily protein MBC directs myoblast fusion through a mechanism that requires phosphatidylinositol 3,4,5-triphosphate binding but is independent of direct interaction with DCrkNeurotrophin-regulated signalling pathwaysRhoG regulates endothelial apical cup assembly downstream from ICAM1 engagement and is involved in leukocyte trans-endothelial migration.Differential activation and function of Rho GTPases during Salmonella-host cell interactionsYersinia pseudotuberculosis spatially controls activation and misregulation of host cell Rac1.Role of MicroRNA in Governing Synaptic PlasticityPhysical view on migration modesThe on-off relationship of Rho and Rac during integrin-mediated adhesion and cell migrationSyndecan-4 signaling at a glanceFunction and regulation of the Rho guanine nucleotide exchange factor TrioThe DOCK protein sponge binds to ELMO and functions in Drosophila embryonic CNS developmentNGF controls dendrite development in hippocampal neurons by binding to p75NTR and modulating the cellular targets of NotchNeuroprotection, Growth Factors and BDNF-TrkB Signalling in Retinal DegenerationDock180 and ELMO1 proteins cooperate to promote evolutionarily conserved Rac-dependent cell migrationThe C-terminal basic tail of RhoG assists the guanine nucleotide exchange factor trio in binding to phospholipidsMolecular association between beta-catenin degradation complex and Rac guanine exchange factor DOCK4 is essential for Wnt/beta-catenin signalingUncoupling of inhibitory and shuttling functions of rho GDP dissociation inhibitorsThe adhesion-GPCR BAI3, a gene linked to psychiatric disorders, regulates dendrite morphogenesis in neuronsP-Rex2 regulates Purkinje cell dendrite morphology and motor coordination.Tiam1 as a signaling mediator of nerve growth factor-dependent neurite outgrowthRac1 is deactivated at integrin activation sites through an IQGAP1-filamin-A-RacGAP1 pathway.The SH3 regulatory domain of the hematopoietic cell kinase Hck binds ELMO via its polyproline motif.The invasive capacity of HPV transformed cells requires the hDlg-dependent enhancement of SGEF/RhoG activity.The N-terminal DH-PH domain of Trio induces cell spreading and migration by regulating lamellipodia dynamics in a Rac1-dependent fashion.
P2860
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P2860
RhoG activates Rac1 by direct interaction with the Dock180-binding protein Elmo
description
2003 nî lūn-bûn
@nan
2003 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
RhoG activates Rac1 by direct interaction with the Dock180-binding protein Elmo
@ast
RhoG activates Rac1 by direct interaction with the Dock180-binding protein Elmo
@en
RhoG activates Rac1 by direct interaction with the Dock180-binding protein Elmo
@en-gb
RhoG activates Rac1 by direct interaction with the Dock180-binding protein Elmo
@nl
type
label
RhoG activates Rac1 by direct interaction with the Dock180-binding protein Elmo
@ast
RhoG activates Rac1 by direct interaction with the Dock180-binding protein Elmo
@en
RhoG activates Rac1 by direct interaction with the Dock180-binding protein Elmo
@en-gb
RhoG activates Rac1 by direct interaction with the Dock180-binding protein Elmo
@nl
prefLabel
RhoG activates Rac1 by direct interaction with the Dock180-binding protein Elmo
@ast
RhoG activates Rac1 by direct interaction with the Dock180-binding protein Elmo
@en
RhoG activates Rac1 by direct interaction with the Dock180-binding protein Elmo
@en-gb
RhoG activates Rac1 by direct interaction with the Dock180-binding protein Elmo
@nl
P3181
P356
P1433
P1476
RhoG activates Rac1 by direct interaction with the Dock180-binding protein Elmo
@en
P2093
Manabu Negishi
P2888
P304
P3181
P356
10.1038/NATURE01817
P407
P577
2003-07-01T00:00:00Z
P6179
1033631719