ELMO1 and Dock180, a bipartite Rac1 guanine nucleotide exchange factor, promote human glioma cell invasion.
about
Ephexin4 and EphA2 mediate cell migration through a RhoG-dependent mechanismPTPmu suppresses glioma cell migration and dispersalApproaches of targeting Rho GTPases in cancer drug discoveryRas superfamily GEFs and GAPs: validated and tractable targets for cancer therapy?The RhoG/ELMO1/Dock180 signaling module is required for spine morphogenesis in hippocampal neurons.Clearance of apoptotic cells: implications in health and diseaseDictyostelium Dock180-related RacGEFs regulate the actin cytoskeleton during cell motility.Tyr724 phosphorylation of ELMO1 by Src is involved in cell spreading and migration via Rac1 activation.Slit2 inhibits glioma cell invasion in the brain by suppression of Cdc42 activity.Regulation of NF-kappaB by NSD1/FBXL11-dependent reversible lysine methylation of p65.Allelic selection of amplicons in glioblastoma revealed by combining somatic and germline analysis.Thiolutin inhibits endothelial cell adhesion by perturbing Hsp27 interactions with components of the actin and intermediate filament cytoskeleton.Early detection of gastric cancer using global, genome-wide and IRF4, ELMO1, CLIP4 and MSC DNA methylation in endoscopic biopsiesmiR-182 as a prognostic marker for glioma progression and patient survival.Essential role of Elmo1 in Dock2-dependent lymphocyte migrationProapoptotic and antiinvasive activity of Rac1 small molecule inhibitors on malignant glioma cellsThe roles of Notch1 expression in the migration of intrahepatic cholangiocarcinomaTROY (TNFRSF19) is overexpressed in advanced glial tumors and promotes glioblastoma cell invasion via Pyk2-Rac1 signaling.RasGRP3 regulates the migration of glioma cells via interaction with Arp3Overexpression of MBD2 in glioblastoma maintains epigenetic silencing and inhibits the antiangiogenic function of the tumor suppressor gene BAI1ELMO1 is upregulated in AML CD34+ stem/progenitor cells, mediates chemotaxis and predicts poor prognosis in normal karyotype AML.PTEN negatively regulates engulfment of apoptotic cells by modulating activation of Rac GTPase.Activation of Rac1 by Src-dependent phosphorylation of Dock180(Y1811) mediates PDGFRα-stimulated glioma tumorigenesis in mice and humans.Phosphorylation of dedicator of cytokinesis 1 (Dock180) at tyrosine residue Y722 by Src family kinases mediates EGFRvIII-driven glioblastoma tumorigenesis.Protein kinase A-dependent phosphorylation of Dock180 at serine residue 1250 is important for glioma growth and invasion stimulated by platelet derived-growth factor receptor α.Cadherin-11, a marker of the mesenchymal phenotype, regulates glioblastoma cell migration and survival in vivo.ELMO3 is a novel biomarker for diagnosis and prognosis of non-small cell lung cancerGenome-Wide Association Study between Single Nucleotide Polymorphisms and Flight Speed in Nellore CattleAutocrine IL-8 promotes F-actin polymerization and mediate mesenchymal transition via ELMO1-NF-κB-Snail signaling in gliomaOverexpression of engulfment and cell motility 1 promotes cell invasion and migration of hepatocellular carcinoma.Tiam1 interaction with the PAR complex promotes talin-mediated Rac1 activation during polarized cell migrationCdc42 and the guanine nucleotide exchange factors Ect2 and trio mediate Fn14-induced migration and invasion of glioblastoma cellsCD151-α3β1 integrin complexes are prognostic markers of glioblastoma and cooperate with EGFR to drive tumor cell motility and invasion.Association between Gαi2 and ELMO1/Dock180 connects chemokine signalling with Rac activation and metastasis.Exome and whole-genome sequencing of esophageal adenocarcinoma identifies recurrent driver events and mutational complexityThe Src homology 3 domain-containing guanine nucleotide exchange factor is overexpressed in high-grade gliomas and promotes tumor necrosis factor-like weak inducer of apoptosis-fibroblast growth factor-inducible 14-induced cell migration and invasioThe guanine nucleotide exchange factors trio, Ect2, and Vav3 mediate the invasive behavior of glioblastoma.ADP-ribosylation factor 6 regulates glioma cell invasion through the IQ-domain GTPase-activating protein 1-Rac1-mediated pathway.Deregulation of Rho GTPases in cancerEGFRvIII stimulates glioma growth and invasion through PKA-dependent serine phosphorylation of Dock180.
P2860
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P2860
ELMO1 and Dock180, a bipartite Rac1 guanine nucleotide exchange factor, promote human glioma cell invasion.
description
2007 nî lūn-bûn
@nan
2007 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
ELMO1 and Dock180, a bipartite ...... ote human glioma cell invasion
@nl
ELMO1 and Dock180, a bipartite ...... te human glioma cell invasion.
@ast
ELMO1 and Dock180, a bipartite ...... te human glioma cell invasion.
@en
type
label
ELMO1 and Dock180, a bipartite ...... ote human glioma cell invasion
@nl
ELMO1 and Dock180, a bipartite ...... te human glioma cell invasion.
@ast
ELMO1 and Dock180, a bipartite ...... te human glioma cell invasion.
@en
prefLabel
ELMO1 and Dock180, a bipartite ...... ote human glioma cell invasion
@nl
ELMO1 and Dock180, a bipartite ...... te human glioma cell invasion.
@ast
ELMO1 and Dock180, a bipartite ...... te human glioma cell invasion.
@en
P2093
P2860
P3181
P1433
P1476
ELMO1 and Dock180, a bipartite ...... te human glioma cell invasion.
@en
P2093
Ifat Bar-Joseph
Kwok-Min Hui
Lisa B Haney
Michael J Jarzynka
Ryo Nishikawa
Shi-Yuan Cheng
Takanori Hirose
Weisong Gu
P2860
P304
P3181
P356
10.1158/0008-5472.CAN-07-0473
P407
P577
2007-08-01T00:00:00Z