Identification of a conserved Rac-binding site on NADPH oxidases supports a direct GTPase regulatory mechanism
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Novel p47(phox)-related organizers regulate localized NADPH oxidase 1 (Nox1) activityEvolution of NADPH Oxidase Inhibitors: Selectivity and Mechanisms for Target EngagementNox family NADPH oxidases in mechano-transduction: mechanisms and consequencesBiochemistry, physiology, and pathophysiology of NADPH oxidases in the cardiovascular systemStructural insights into Nox4 and Nox2: motifs involved in function and cellular localizationTargeting and regulation of reactive oxygen species generation by Nox family NADPH oxidases.Emerging evidence for the importance of phosphorylation in the regulation of NADPH oxidases.A novel and specific NADPH oxidase-1 (Nox1) small-molecule inhibitor blocks the formation of functional invadopodia in human colon cancer cellsA prenylated p47phox-p67phox-Rac1 chimera is a Quintessential NADPH oxidase activator: membrane association and functional capacity.A conserved region between the TPR and activation domains of p67phox participates in activation of the phagocyte NADPH oxidase.c-Src-mediated phosphorylation of NoxA1 and Tks4 induces the reactive oxygen species (ROS)-dependent formation of functional invadopodia in human colon cancer cells.Nicotinamide adenine dinucleotide phosphate reduced oxidase 5 (Nox5) regulation by angiotensin II and endothelin-1 is mediated via calcium/calmodulin-dependent, rac-1-independent pathways in human endothelial cells.NOX Modifiers-Just a Step Away from Application in the Therapy of Airway Inflammation?The involvement of the tyrosine kinase c-Src in the regulation of reactive oxygen species generation mediated by NADPH oxidase-1.Suppressed hindlimb perfusion in Rac2-/- and Nox2-/- mice does not result from impaired collateral growth.Regulation of the phagocyte NADPH oxidase activity: phosphorylation of gp91phox/NOX2 by protein kinase C enhances its diaphorase activity and binding to Rac2, p67phox, and p47phox.Role of Rac1 GTPase in JNK signaling and delayed neuronal cell death following global cerebral ischemia.Genetic silencing of Nox2 and Nox4 reveals differential roles of these NADPH oxidase homologues in the vasopressor and dipsogenic effects of brain angiotensin II.NADPH oxidase in brain injury and neurodegenerative disordersStrategies for identifying synthetic peptides to act as inhibitors of NADPH oxidases, or "all that you did and did not want to know about Nox inhibitory peptides".Towards specific NADPH oxidase inhibition by small synthetic peptides.Role of the Rho GTPase Rac in the activation of the phagocyte NADPH oxidase: outsourcing a key task.Neuregulin induces HaCaT keratinocyte migration via Rac1-mediated NADPH-oxidase activation.Role of Transient Receptor Potential Vanilloid 4 in Neutrophil Activation and Acute Lung Injury.Rational design of small molecule inhibitors targeting the Rac GTPase-p67(phox) signaling axis in inflammation.Inhibition of NADPH oxidase activation by peptides mapping within the dehydrogenase region of Nox2-A "peptide walking" study.NADPH oxidase expression and production of superoxide by human corneal stromal cells.Innate immunity and the evolution of resistance to an emerging infectious disease in a wild bird.RCC2 over-expression in tumor cells alters apoptosis and drug sensitivity by regulating Rac1 activation.RAC2:GTP binds NOX2 complexProduction of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTPRAC1:GTP binds NOX1 complexRAC1:GTP binds NOX3 complexNOX3 complex:RAC1:GTP generates superoxide from oxygenExendin-4 alleviates angiotensin II-induced senescence in vascular smooth muscle cells by inhibiting Rac1 activation via a cAMP/PKA-dependent pathway.
P2860
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P2860
Identification of a conserved Rac-binding site on NADPH oxidases supports a direct GTPase regulatory mechanism
description
2008 nî lūn-bûn
@nan
2008 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Identification of a conserved ...... ct GTPase regulatory mechanism
@ast
Identification of a conserved ...... ct GTPase regulatory mechanism
@en
Identification of a conserved ...... ct GTPase regulatory mechanism
@en-gb
Identification of a conserved ...... ct GTPase regulatory mechanism
@nl
type
label
Identification of a conserved ...... ct GTPase regulatory mechanism
@ast
Identification of a conserved ...... ct GTPase regulatory mechanism
@en
Identification of a conserved ...... ct GTPase regulatory mechanism
@en-gb
Identification of a conserved ...... ct GTPase regulatory mechanism
@nl
prefLabel
Identification of a conserved ...... ct GTPase regulatory mechanism
@ast
Identification of a conserved ...... ct GTPase regulatory mechanism
@en
Identification of a conserved ...... ct GTPase regulatory mechanism
@en-gb
Identification of a conserved ...... ct GTPase regulatory mechanism
@nl
P2093
P2860
P921
P356
P1476
Identification of a conserved ...... ct GTPase regulatory mechanism
@en
P2093
Benjamin Bohl
Davide Gianni
Gary M Bokoch
Ross M Taylor
P2860
P304
P356
10.1074/JBC.M801010200
P407
P577
2008-05-09T00:00:00Z