Evolution of NADPH Oxidase Inhibitors: Selectivity and Mechanisms for Target Engagement - Test2 - elhamkhani - TriplyDB

Evolution of NADPH Oxidase Inhibitors: Selectivity and Mechanisms for Target Engagement

Evolution of NADPH Oxidase Inhibitors: Selectivity and Mechanisms for Target Engagement

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Cerebral Small Vessel Disease: Targeting Oxidative Stress as a Novel Therapeutic Strategy?Pharmacology and Clinical Drug Candidates in Redox Medicine Organic Nitrate Therapy, Nitrate Tolerance, and Nitrate-Induced Endothelial Dysfunction: Emphasis on Redox Biology and Oxidative Stress Role of NADPH oxidases in the redox biology of liver fibrosis Redox signaling, Nox5 and vascular remodeling in hypertension Oxidative Stress and the Use of Antioxidants in Stroke Mitochondrial reactive oxygen species: a double edged sword in ischemia/reperfusion vs preconditioning Reactive Oxygen-Related Diseases: Therapeutic Targets and Emerging Clinical Indications Amyloid-β and proinflammatory cytokines utilize a prion protein-dependent pathway to activate NADPH oxidase and induce cofilin-actin rods in hippocampal neurons NADPH oxidases: key modulators in aging and age-related cardiovascular diseases?Evidence for the free radical/oxidative stress theory of ageing from the CHANCES consortium: a meta-analysis of individual participant data Skin Antiageing and Systemic Redox Effects of Supplementation with Marine Collagen Peptides and Plant-Derived Antioxidants: A Single-Blind Case-Control Clinical Study.Hu antigen R is required for NOX-1 but not NOX-4 regulation by inflammatory stimuli in vascular smooth muscle cells.Ultra-weak photon emission as a dynamic tool for monitoring oxidative stress metabolism.Crossroads between peripheral atherosclerosis, western-type diet and skeletal muscle pathophysiology: emphasis on apolipoprotein E deficiency and peripheral arterial disease.Tetramethylpyrazine Protects against Hydrogen Peroxide-Provoked Endothelial Dysfunction in Isolated Rat Aortic Rings: Implications for Antioxidant Therapy of Vascular Diseases Updates of reactive oxygen species in melanoma etiology and progression.Inhibition of NOX1/4 with GKT137831: a potential novel treatment to attenuate neuroglial cell inflammation in the retina.Redox-based therapeutics in neurodegenerative disease.Oxidative stress-dependent activation of collagen synthesis is induced in human pulmonary smooth muscle cells by sera from patients with scleroderma-associated pulmonary hypertension.Nox Inhibitors & Therapies: Rational Design of Peptidic and Small Molecule Inhibitors Regulation of Nox enzymes expression in vascular pathophysiology: Focusing on transcription factors and epigenetic mechanisms.Mitigation of NADPH Oxidase 2 Activity as a Strategy to Inhibit Peroxynitrite Formation.Discovery of GSK2795039, a Novel Small Molecule NADPH Oxidase 2 Inhibitor.Cluster Differentiating 36 (CD36) Deficiency Attenuates Obesity-Associated Oxidative Stress in the Heart.Recent developments in detection of superoxide radical anion and hydrogen peroxide: Opportunities, challenges, and implications in redox signaling.Reperfusion injury and reactive oxygen species: The evolution of a concept.Celastrol ameliorates Cd-induced neuronal apoptosis by targeting NOX2-derived ROS-dependent PP5-JNK signaling pathway.Oxidant and Inflammatory Mechanisms and Targeted Therapy in Atrial Fibrillation: An Update.Apocynin and Diphenyleneiodonium Induce Oxidative Stress and Modulate PI3K/Akt and MAPK/Erk Activity in Mouse Embryonic Stem Cells.A NOX2/Egr-1/Fyn pathway delineates new targets for TKI-resistant malignancies Neutrophil extracellular traps enriched in oxidized mitochondrial DNA are interferogenic and contribute to lupus-like disease.Anti-Inflammatory Small Molecules To Treat Seizures and Epilepsy: From Bench to Bedside DUOX1 mediates persistent epithelial EGFR activation, mucous cell metaplasia, and airway remodeling during allergic asthma.Deficiency in Duox2 activity alleviates ileitis in GPx1- and GPx2-knockout mice without affecting apoptosis incidence in the crypt epithelium.NADPH oxidase in brain injury and neurodegenerative disorders Skeletal muscle aging: influence of oxidative stress and physical exercise.Role of cellular senescence and NOX4-mediated oxidative stress in systemic sclerosis pathogenesis.NADPH oxidases and cancer.Heparan Sulfate Proteoglycan Deficiency Up-Regulates the Intracellular Production of Nitric Oxide in Chinese Hamster Ovary Cell Lines.

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Evolution of NADPH Oxidase Inhibitors: Selectivity and Mechanisms for Target Engagement

http://www.wikidata.org/entity/Q26861119

description

2015 nî lūn-bûn

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2015 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

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2015 թվականի օգոստոսին հրատարակված գիտական հոդված

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2015年の論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年论文

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name

Evolution of NADPH Oxidase Inhibitors: Selectivity and Mechanisms for Target Engagement

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Evolution of NADPH Oxidase Inhibitors: Selectivity and Mechanisms for Target Engagement

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Evolution of NADPH Oxidase Inhibitors: Selectivity and Mechanisms for Target Engagement

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Evolution of NADPH Oxidase Inhibitors: Selectivity and Mechanisms for Target Engagement

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Evolution of NADPH Oxidase Inhibitors: Selectivity and Mechanisms for Target Engagement

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Evolution of NADPH Oxidase Inhibitors: Selectivity and Mechanisms for Target Engagement

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Evolution of NADPH Oxidase Inhibitors: Selectivity and Mechanisms for Target Engagement

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Evolution of NADPH Oxidase Inhibitors: Selectivity and Mechanisms for Target Engagement

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Evolution of NADPH Oxidase Inhibitors: Selectivity and Mechanisms for Target Engagement

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Antioxidants & Redox Signaling

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Evolution of NADPH Oxidase Inhibitors: Selectivity and Mechanisms for Target Engagement

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Harald H.H.W. Schmidt

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Kim A. Radermacher

http://www.w3.org/2001/XMLSchema#string

Kirstin Wingler

http://www.w3.org/2001/XMLSchema#string

Pamela W.M. Kleikers

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Sebastian Altenhöfer

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Apocynin: molecular aptitudes

A Ca(2+)-activated NADPH oxidase in testis, spleen, and lymph nodes

NADPH oxidase 5 (NOX5) interacts with and is regulated by calmodulin

Identification of a conserved Rac-binding site on NADPH oxidases supports a direct GTPase regulatory mechanism

Novel p47(phox)-related organizers regulate localized NADPH oxidase 1 (Nox1) activity

Involvement of Rac1 in activation of multicomponent Nox1- and Nox3-based NADPH oxidases

A tissue-scale gradient of hydrogen peroxide mediates rapid wound detection in zebrafish.

Caenorhabditis elegans and human dual oxidase 1 (DUOX1) "peroxidase" domains: insights into heme binding and catalytic activity

Critical roles for p22phox in the structural maturation and subcellular targeting of Nox3

Neuroprotection for stroke: current status and future perspectives

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406-27

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scholarly article

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1506166

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10.1089/ARS.2013.5814

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5

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23

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2015-08-10T00:00:00Z

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259565548

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24383718

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4543484

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