ATM-dependent expression of IEX-1 controls nuclear accumulation of Mcl-1 and the DNA damage response
about
BID binds to replication protein A and stimulates ATR function following replicative stressStress-induced hematopoietic failure in the absence of immediate early response gene X-1 (IEX-1, IER3)Mitoquinone restores platelet production in irradiation-induced thrombocytopenia.Defective endomitosis during megakaryopoiesis leads to thrombocytopenia in Fanca-/- mice.Scaffold protein FHL2 facilitates MDM2-mediated degradation of IER3 to regulate proliferation of cervical cancer cells.Impairment of the activin A autocrine loop by lopinavir reduces self-renewal of distinct human adipose progenitors.Obatoclax potentiates the cytotoxic effect of cytarabine on acute myeloid leukemia cells by enhancing DNA damage.IER3 is a crucial mediator of TAp73β-induced apoptosis in cervical cancer and confers etoposide sensitivity.Immediate early response gene X-1, a potential prognostic biomarker in cancersThrombopoietin promotes NHEJ DNA repair in hematopoietic stem cells through specific activation of Erk and NF-κB pathways and their target, IEX-1Resistance of Sézary cells to TNF-α-induced apoptosis is mediated in part by a loss of TNFR1 and a high level of the IER3 expressionNucleoporin NUP153 guards genome integrity by promoting nuclear import of 53BP1MCL-1 Depletion Impairs DNA Double-Strand Break Repair and Reinitiation of Stalled DNA Replication Forks.Inactivation of nuclear GSK3β by Ser(389) phosphorylation promotes lymphocyte fitness during DNA double-strand break responseIdelalisib and bendamustine combination is synergistic and increases DNA damage response in chronic lymphocytic leukemia cells.The Viral Bcl-2 Homologs of Kaposi's Sarcoma-Associated Herpesvirus and Rhesus Rhadinovirus Share an Essential Role for Viral Replication.Comprehensive identification of genes driven by ERV9-LTRs reveals TNFRSF10B as a re-activatable mediator of testicular cancer cell death.Dual PI3K/ERK inhibition induces necroptotic cell death of Hodgkin Lymphoma cells through IER3 downregulation.Subcellular dynamics of the maternal cell death regulator BCL2L10 in human preimplantation embryos.Association of anti-apoptotic Mcl-1L isoform expression with radioresistance of oral squamous carcinoma cells.Mcl-1 protects prostate cancer cells from cell death mediated by chemotherapy-induced DNA damage.Mcl-1 suppresses abasic site repair following bile acid-induced hepatic cellular DNA damage.Targeting Mcl-1 enhances DNA replication stress sensitivity to cancer therapy.IER3 Promotes Expansion of Adipose Progenitor Cells in Response to Changes in Distinct Microenvironmental Effectors.Identifying the druggable interactome of EWS-FLI1 reveals MCL-1 dependent differential sensitivities of Ewing sarcoma cells to apoptosis inducers
P2860
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P248
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P2860
ATM-dependent expression of IEX-1 controls nuclear accumulation of Mcl-1 and the DNA damage response
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2010 nî lūn-bûn
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2010 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
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2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
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ATM-dependent expression of IE ...... -1 and the DNA damage response
@ast
ATM-dependent expression of IE ...... -1 and the DNA damage response
@en
ATM-dependent expression of IE ...... -1 and the DNA damage response
@en-gb
ATM-dependent expression of IE ...... -1 and the DNA damage response
@nl
type
label
ATM-dependent expression of IE ...... -1 and the DNA damage response
@ast
ATM-dependent expression of IE ...... -1 and the DNA damage response
@en
ATM-dependent expression of IE ...... -1 and the DNA damage response
@en-gb
ATM-dependent expression of IE ...... -1 and the DNA damage response
@nl
prefLabel
ATM-dependent expression of IE ...... -1 and the DNA damage response
@ast
ATM-dependent expression of IE ...... -1 and the DNA damage response
@en
ATM-dependent expression of IE ...... -1 and the DNA damage response
@en-gb
ATM-dependent expression of IE ...... -1 and the DNA damage response
@nl
P2093
P2860
P921
P3181
P356
P1476
ATM-dependent expression of IE ...... -1 and the DNA damage response
@en
P2093
B de Laval
F Rosselli
P Pawlikowska
P2860
P2888
P304
P3181
P356
10.1038/CDD.2010.56
P407
P577
2010-11-01T00:00:00Z
P5875
P6179
1000263418