P688
Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic functionApoptosis initiated when BH3 ligands engage multiple Bcl-2 homologs, not Bax or BakPrevention of cytokine withdrawal-induced apoptosis by Mcl-1 requires interaction between Mcl-1 and BimProapoptotic Bak is sequestered by Mcl-1 and Bcl-xL, but not Bcl-2, until displaced by BH3-only proteins.BH3 domains other than Bim and Bid can directly activate Bax/BakGlycogen synthase kinase-3 regulates mitochondrial outer membrane permeabilization and apoptosis by destabilization of MCL-1Parkin-dependent degradation of the F-box protein Fbw7β promotes neuronal survival in response to oxidative stress by stabilizing Mcl-1The apoptosis and proliferation of SAC-activated B cells by IL-10 are associated with changes in Bcl-2, Bcl-xL, and Mcl-1 expressionATM-dependent expression of IEX-1 controls nuclear accumulation of Mcl-1 and the DNA damage responseThe intracellular distribution and pattern of expression of Mcl-1 overlap with, but are not identical to, those of Bcl-2The fast-mobility isoform of mouse Mcl-1 is a mitochondrial matrix-localized protein with attenuated anti-apoptotic activityStructural insights into the degradation of Mcl-1 induced by BH3 domainsPro-apoptotic activity of inhibitory PAS domain protein (IPAS), a negative regulator of HIF-1, through binding to pro-survival Bcl-2 family proteinsBOK Is a Non-canonical BCL-2 Family Effector of Apoptosis Regulated by ER-Associated DegradationGoofy coordinates the acuity of olfactory signaling
P921
Q24293924-3D69E4D4-BFD7-4F5E-91E5-D349A390DC7BQ24296478-39653415-E53D-43D9-BD8C-08318C8FC9EAQ24301935-6BCE5C83-681D-4EE7-A251-D00DAC470C8BQ24302494-FB139D07-6C72-4D34-8D6B-33570741026FQ24305138-7A8F6C07-D068-439C-B315-94D8C91E2DC9Q24308005-316E6B2E-200C-40A9-B7B4-F1EDA0F356E8Q24308897-9E222E9D-A0B1-4DB9-A831-6E63B84DBF74Q24310135-AC509E6E-B97E-4F25-8DBD-29A7D0E1AC6AQ24312475-4E42AEF2-087C-47FC-8991-9CF43756663FQ24317954-BD4CAAD4-4C6C-4514-B361-7EA243420945Q24338742-7231ED17-50D3-4D9E-80A7-785091DAE646Q27644256-86616D2C-C692-4C57-ACB4-A1153DC85FD5Q28508093-773054CF-F56A-414D-9758-5594D3E5BA79Q28593563-824E592E-B001-4517-BB7E-9AA8573CE1AFQ28593697-0C1CE981-BE10-4022-BBB8-553041DA346E
P921
description
mammalian protein found in Mus musculus
@en
protein
@id
proteinë
@sq
proteïne in Myeloid cell leukemia sequence 1
@nl
protèin
@ace
بروتين في فأر المنازل
@ar
name
Myeloid cell leukemia sequence 1
@en
Myeloid cell leukemia sequence 1
@nl
type
label
Myeloid cell leukemia sequence 1
@en
Myeloid cell leukemia sequence 1
@nl
altLabel
Mcl1
@en
bcl-2-related protein EAT/mcl1
@en
induced myeloid leukemia cell differentiation protein Mcl-1 homolog
@en
prefLabel
Myeloid cell leukemia sequence 1
@en
Myeloid cell leukemia sequence 1
@nl
P361
P527
P638
P680
P681
P682
P352
P31
P352
P527
P637
XP_006501151
P638
P680
P681
P682
P702
P703
P705
ENSMUSP00000044048
ENSMUSP00000135915