Substrate specificity and structure of human aminoadipate aminotransferase/kynurenine aminotransferase II
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Structural insight into the inhibition of human kynurenine aminotransferase I/glutamine transaminase KBiochemical and structural properties of mouse kynurenine aminotransferase IIIKynurenine Aminotransferase Isozyme Inhibitors: A Reviewα-Ketoglutaramate: an overlooked metabolite of glutamine and a biomarker for hepatic encephalopathy and inborn errors of the urea cycleStructure, expression, and function of kynurenine aminotransferases in human and rodent brainsCrystal Structure-Based Selective Targeting of the Pyridoxal 5′-Phosphate Dependent Enzyme Kynurenine Aminotransferase II for Cognitive EnhancementBiochemical and structural characterization of mouse mitochondrial aspartate aminotransferase, a newly identified kynurenine aminotransferase-IVCrystal structure ofSaccharomyces cerevisiaeAro8, a putative α-aminoadipate aminotransferaseThermal stability, pH dependence and inhibition of four murine kynurenine aminotransferasesKynurenine Pathway of Tryptophan Metabolism: Regulatory and Functional Aspects.Kynurenine aminotransferase III and glutamine transaminase L are identical enzymes that have cysteine S-conjugate β-lyase activity and can transaminate L-selenomethionineActivation of the kynurenine pathway and increased production of the excitotoxin quinolinic acid following traumatic brain injury in humans.Tryptophan catabolism in Pseudomonas aeruginosa and potential for inter-kingdom relationship.Comparative enzymology of (2S,4R)4-fluoroglutamine and (2S,4R)4-fluoroglutamate.A mathematical model of tryptophan metabolism via the kynurenine pathway provides insights into the effects of vitamin B-6 deficiency, tryptophan loading, and induction of tryptophan 2,3-dioxygenase on tryptophan metabolitesQuantification of mitochondrial acetylation dynamics highlights prominent sites of metabolic regulationAssessment of the Human Kynurenine Pathway: Comparisons and Clinical Implications of Ethnic and Gender Differences in Plasma Tryptophan, Kynurenine Metabolites, and Enzyme Expressions at Baseline and After Acute Tryptophan Loading and DepletionKynurenines with neuroactive and redox properties: relevance to aging and brain diseases.Lysine metabolism in mammalian brain: an update on the importance of recent discoveries.ω-Amidase: an underappreciated, but important enzyme in L-glutamine and L-asparagine metabolism; relevance to sulfur and nitrogen metabolism, tumor biology and hyperammonemic diseases.Structure of the PLP-Form of the Human Kynurenine Aminotransferase II in a Novel Spacegroup at 1.83 Å Resolution.On the relationship between the two branches of the kynurenine pathway in the rat brain in vivo.Kynurenine aminotransferase activity of Aro8/Aro9 engage tryptophan degradation by producing kynurenic acid in Saccharomyces cerevisiae.Fluorination at the 4 position alters the substrate behavior of L-glutamine and L-glutamate: Implications for positron emission tomography of neoplasias.Xanthurenic Acid Formation from 3-Hydroxykynurenine in the Mammalian Brain: Neurochemical Characterization and Physiological Effects.High resolution crystal structures of human kynurenine aminotransferase-I bound to PLP cofactor, and in complex with aminooxyacetate.Oral administration of a specific kynurenic acid synthesis (KAT II) inhibitor attenuates evoked glutamate release in rat prefrontal cortex.Multi-platform mass spectrometry analysis of the CSF and plasma metabolomes of rigorously matched amyotrophic lateral sclerosis, Parkinson's disease and control subjects.Human kynurenine aminotransferase II - reactivity with substrates and inhibitorsRelevance of Alternative Routes of Kynurenic Acid Production in the Brain.
P2860
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P2860
Substrate specificity and structure of human aminoadipate aminotransferase/kynurenine aminotransferase II
description
2008 nî lūn-bûn
@nan
2008 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Substrate specificity and stru ...... kynurenine aminotransferase II
@ast
Substrate specificity and stru ...... kynurenine aminotransferase II
@en
Substrate specificity and stru ...... kynurenine aminotransferase II
@en-gb
Substrate specificity and stru ...... kynurenine aminotransferase II
@nl
type
label
Substrate specificity and stru ...... kynurenine aminotransferase II
@ast
Substrate specificity and stru ...... kynurenine aminotransferase II
@en
Substrate specificity and stru ...... kynurenine aminotransferase II
@en-gb
Substrate specificity and stru ...... kynurenine aminotransferase II
@nl
prefLabel
Substrate specificity and stru ...... kynurenine aminotransferase II
@ast
Substrate specificity and stru ...... kynurenine aminotransferase II
@en
Substrate specificity and stru ...... kynurenine aminotransferase II
@en-gb
Substrate specificity and stru ...... kynurenine aminotransferase II
@nl
P2093
P2860
P921
P3181
P356
P1433
P1476
Substrate specificity and stru ...... kynurenine aminotransferase II
@en
P2093
Danilo A Tagle
Howard Robinson
Jianyong Li
P2860
P304
P3181
P356
10.1042/BSR20080085
P407
P577
2008-08-01T00:00:00Z