Structure, expression, and function of kynurenine aminotransferases in human and rodent brains - Test2 - elhamkhani - TriplyDB

Structure, expression, and function of kynurenine aminotransferases in human and rodent brains

Structure, expression, and function of kynurenine aminotransferases in human and rodent brains

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Kynurenine Aminotransferase Isozyme Inhibitors: A Review Kynurenines and Multiple Sclerosis: The Dialogue between the Immune System and the Central Nervous System Kynurenines in the mammalian brain: when physiology meets pathology Biochemical and structural characterization of mouse mitochondrial aspartate aminotransferase, a newly identified kynurenine aminotransferase-IV Tyrosine aminotransferase: biochemical and structural properties and molecular dynamics simulations Biochemical identification and crystal structure of kynurenine formamidase from Drosophila melanogaster Structure-Based Design of Irreversible Human KAT II Inhibitors: Discovery of New Potency-Enhancing Interactions Fluctuations in endogenous kynurenic acid control hippocampal glutamate and memory Thermal stability, pH dependence and inhibition of four murine kynurenine aminotransferases The presence of kynurenine aminotransferases in the human cornea: Evidence from bioinformatics analysis of gene expression and immunohistochemical staining.Characteristic features of kynurenine aminotransferase allosterically regulated by (alpha)-ketoglutarate in cooperation with kynurenine Interferon-gamma-inducible kynurenines/pteridines inflammation cascade: implications for aging and aging-associated psychiatric and medical disorders.A meta-analysis of thyroid-related traits reveals novel loci and gender-specific differences in the regulation of thyroid function Age dependency of inhibition of alpha7 nicotinic receptors and tonically active N-methyl-D-aspartate receptors by endogenously produced kynurenic acid in the brain Impaired kynurenine pathway metabolism in the prefrontal cortex of individuals with schizophrenia.Alternative kynurenic acid synthesis routes studied in the rat cerebellum.Activation of the kynurenine pathway and increased production of the excitotoxin quinolinic acid following traumatic brain injury in humans.Kynurenic acid and 3-hydroxykynurenine production from D-kynurenine in mice.Ketogenic diet increases concentrations of kynurenic acid in discrete brain structures of young and adult rats.Branched-chain amino acids alter neurobehavioral function in rats Endogenous neuroprotection in chronic neurodegenerative disorders: with particular regard to the kynurenines.Kynurenines, neurodegeneration and Alzheimer's disease.Kynurenines in Parkinson's disease: therapeutic perspectives.The role of kynurenines in the pathomechanism of amyotrophic lateral sclerosis and multiple sclerosis: therapeutic implications.Kynurenic acid as an antagonist of α7 nicotinic acetylcholine receptors in the brain: facts and challenges.The causative role and therapeutic potential of the kynurenine pathway in neurodegenerative disease.Lysine metabolism in mammalian brain: an update on the importance of recent discoveries.Alzheimer's and seizures: interleukin-18, indoleamine 2,3-dioxygenase and quinolinic Acid Major developments in the design of inhibitors along the kynurenine pathway.The kynurenine pathway and the brain: Challenges, controversies and promises.Inhibitors of the kynurenine pathway as neurotherapeutics: a patent review (2012-2015).Kynurenines and Glutamate: Multiple Links and Therapeutic Implications.Abnormal kynurenine pathway of tryptophan catabolism in cardiovascular diseases.Kynurenines and other novel therapeutic strategies in the treatment of dementia.Interleukin-1β: a new regulator of the kynurenine pathway affecting human hippocampal neurogenesis.Characterization of the kynurenine pathway in NSC-34 cell line: implications for amyotrophic lateral sclerosis.Discovery of Brain-Penetrant, Irreversible Kynurenine Aminotransferase II Inhibitors for Schizophrenia.Efficient gene-targeting in rat embryonic stem cells by CRISPR/Cas and generation of human kynurenine aminotransferase II (KAT II) knock-in rat.Structure of the PLP-Form of the Human Kynurenine Aminotransferase II in a Novel Spacegroup at 1.83 Å Resolution.Kynurenine aminotransferase 3/glutamine transaminase L/cysteine conjugate beta-lyase 2 is a major glutamine transaminase in the mouse kidney.

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Structure, expression, and function of kynurenine aminotransferases in human and rodent brains

http://www.wikidata.org/entity/Q27657768

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2010 nî lūn-bûn

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2010 թվականի փետրվարին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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Structure, expression, and fun ...... ses in human and rodent brains

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Structure, expression, and fun ...... ses in human and rodent brains

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Structure, expression, and fun ...... ses in human and rodent brains

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Structure, expression, and fun ...... ses in human and rodent brains

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Structure, expression, and fun ...... ses in human and rodent brains

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Structure, expression, and fun ...... ses in human and rodent brains

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Danilo A Tagle

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Jianyong Li

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The α-Aminoadipate Pathway for Lysine Biosynthesis in Fungi

Crystal structure of human kynurenine aminotransferase I

Structural insight into the inhibition of human kynurenine aminotransferase I/glutamine transaminase K

Substrate specificity and structure of human aminoadipate aminotransferase/kynurenine aminotransferase II

Molecular cloning and expression of a cDNA for human kidney cysteine conjugate beta-lyase

Kynurenic acid as a ligand for orphan G protein-coupled receptor GPR35

Modulation of the function of presynaptic alpha7 and non-alpha7 nicotinic receptors by the tryptophan metabolites, 5-hydroxyindole and kynurenate in mouse brain

Structural insight into the mechanism of substrate specificity of aedes kynurenine aminotransferase

Biochemical and structural properties of mouse kynurenine aminotransferase III

Mammalian nicotinic acetylcholine receptors: from structure to function

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