Immunodeficiency and chronic myelogenous leukemia-like syndrome in mice with a targeted mutation of the ICSBP gene
about
The genetic association of variants in CD6, TNFRSF1A and IRF8 to multiple sclerosis: a multicenter case-control studyInositol hexakisphosphate kinase 2 mediates growth suppressive and apoptotic effects of interferon-beta in ovarian carcinoma cellsThe cell death regulator GRIM-19 is an inhibitor of signal transducer and activator of transcription 3Virus-dependent phosphorylation of the IRF-3 transcription factor regulates nuclear translocation, transactivation potential, and proteasome-mediated degradationDido gene expression alterations are implicated in the induction of hematological myeloid neoplasmsFunctional domains of interferon regulatory factor I (IRF-1)Direct triggering of the type I interferon system by virus infection: activation of a transcription factor complex containing IRF-3 and CBP/p300.Assembly requirements of PU.1-Pip (IRF-4) activator complexes: inhibiting function in vivo using fused dimersThe histone acetylase PCAF is a phorbol-ester-inducible coactivator of the IRF family that confers enhanced interferon responsivenessIRF8 regulates acid ceramidase expression to mediate apoptosis and suppresses myelogeneous leukemiaId2 expression delineates differential checkpoints in the genetic program of CD8α+ and CD103+ dendritic cell lineagesCutting edge: IRF8 regulates Bax transcription in vivo in primary myeloid cellsIFN regulatory factor 8 sensitizes soft tissue sarcoma cells to death receptor-initiated apoptosis via repression of FLICE-like protein expressionDNA methylation represses IFN-gamma-induced and signal transducer and activator of transcription 1-mediated IFN regulatory factor 8 activation in colon carcinoma cellsLeukemia-associated, constitutively active mutants of SHP2 protein tyrosine phosphatase inhibit NF1 transcriptional activation by the interferon consensus sequence binding proteinICSBP is essential for the development of mouse type I interferon-producing cells and for the generation and activation of CD8alpha(+) dendritic cellsAbnormal skin, limb and craniofacial morphogenesis in mice deficient for interferon regulatory factor 6 (Irf6)The IRF family, revisitedDown-regulation of interferon regulatory factor 4 gene expression in leukemic cells due to hypermethylation of CpG motifs in the promoter regionSLE-associated risk factors affect DC functionMolecular control of monocyte developmentInterferon-regulatory factors determine macrophage phenotype polarizationMicroglia development and functionInterferon regulatory factor 8-deficiency determines massive neutrophil recruitment but T cell defect in fast growing granulomas during tuberculosisCharacterization of the interferon regulatory factor-7 and its potential role in the transcription activation of interferon A genesInterferon regulatory factor 8 (IRF8) interacts with the B cell lymphoma 6 (BCL6) corepressor BCORRegulation of the promoter activity of interferon regulatory factor-7 gene. Activation by interferon snd silencing by hypermethylationInteraction between interferon consensus sequence-binding protein and COP9/signalosome subunit CSN2 (Trip15). A possible link between interferon regulatory factor signaling and the COP9/signalosomeInterferon consensus sequence-binding protein is constitutively expressed and differentially regulated in the ocular lensPU.1 and interferon consensus sequence-binding protein regulate the myeloid expression of the human Toll-like receptor 4 geneMultiple Ets factors and interferon regulatory factor-4 modulate CD68 expression in a cell type-specific mannerUbiquitin-dependent degradation of interferon regulatory factor-8 mediated by Cbl down-regulates interleukin-12 expressionInhibition of monocytic differentiation by phosphorylation-deficient Stat1 is associated with impaired expression of Stat2, ICSBP/IRF8 and C/EBPepsilonPU.1, interferon regulatory factor (IRF) 2, and the interferon consensus sequence-binding protein (ICSBP/IRF8) cooperate to activate NF1 transcription in differentiating myeloid cellsThe interferon consensus sequence-binding protein activates transcription of the gene encoding neurofibromin 1Atovaquone nanosuspensions show excellent therapeutic effect in a new murine model of reactivated toxoplasmosisLSK derived LSK- cells have a high apoptotic rate related to survival regulation of hematopoietic and leukemic stem cellsDisabled-2 is transcriptionally regulated by ICSBP and augments macrophage spreading and adhesion.A mutation in the Icsbp1 gene causes susceptibility to infection and a chronic myeloid leukemia-like syndrome in BXH-2 miceInterferon consensus sequence binding protein-deficient mice display impaired resistance to intracellular infection due to a primary defect in interleukin 12 p40 induction
P2860
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P2860
Immunodeficiency and chronic myelogenous leukemia-like syndrome in mice with a targeted mutation of the ICSBP gene
description
1996 nî lūn-bûn
@nan
1996 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
name
Immunodeficiency and chronic m ...... ted mutation of the ICSBP gene
@ast
Immunodeficiency and chronic m ...... ted mutation of the ICSBP gene
@en
Immunodeficiency and chronic m ...... ted mutation of the ICSBP gene
@en-gb
Immunodeficiency and chronic m ...... ted mutation of the ICSBP gene
@nl
type
label
Immunodeficiency and chronic m ...... ted mutation of the ICSBP gene
@ast
Immunodeficiency and chronic m ...... ted mutation of the ICSBP gene
@en
Immunodeficiency and chronic m ...... ted mutation of the ICSBP gene
@en-gb
Immunodeficiency and chronic m ...... ted mutation of the ICSBP gene
@nl
prefLabel
Immunodeficiency and chronic m ...... ted mutation of the ICSBP gene
@ast
Immunodeficiency and chronic m ...... ted mutation of the ICSBP gene
@en
Immunodeficiency and chronic m ...... ted mutation of the ICSBP gene
@en-gb
Immunodeficiency and chronic m ...... ted mutation of the ICSBP gene
@nl
P2093
P921
P3181
P1433
P1476
Immunodeficiency and chronic m ...... ted mutation of the ICSBP gene
@en
P2093
F Rosenbauer
J F Waring
K P Knobeloch
M F Bachmann
P304
P3181
P356
10.1016/S0092-8674(00)81348-3
P407
P577
1996-10-18T00:00:00Z