Endosomal WASH and exocyst complexes control exocytosis of MT1-MMP at invadopodia.
about
The regulation of MMP targeting to invadopodia during cancer metastasisVARP is recruited on to endosomes by direct interaction with retromer, where together they function in export to the cell surfaceCLASPs link focal-adhesion-associated microtubule capture to localized exocytosis and adhesion site turnoverThe Exocyst Complex in Health and DiseaseThe Exocyst at a GlanceMetalloproteinase MT1-MMP islets act as memory devices for podosome reemergenceARF6-JIP3/4 regulate endosomal tubules for MT1-MMP exocytosis in cancer invasion.Podoplanin mediates ECM degradation by squamous carcinoma cells through control of invadopodia stabilityPI(3,5)P2 controls endosomal branched actin dynamics by regulating cortactin-actin interactions.ARF6 promotes the formation of Rac1 and WAVE-dependent ventral F-actin rosettes in breast cancer cells in response to epidermal growth factorTOM1L1 drives membrane delivery of MT1-MMP to promote ERBB2-induced breast cancer cell invasion.Ral GTPases: crucial mediators of exocytosis and tumourigenesisA RAB5/RAB4 recycling circuitry induces a proteolytic invasive program and promotes tumor dissemination.Protein-tyrosine pseudokinase 7 (PTK7) directs cancer cell motility and metastasis.Discoidin domain receptor 1 controls linear invadosome formation via a Cdc42-Tuba pathway.Nuclear envelope-associated endosomes deliver surface proteins to the nucleus.5'-Inositol phosphatase SHIP2 recruits Mena to stabilize invadopodia for cancer cell invasion.p53 in cell invasion, podosomes, and invadopodiaInvadopodia and basement membrane invasion in vivo.Nuclear FAM21 participates in NF-κB-dependent gene regulation in pancreatic cancer cells.Dense fibrillar collagen is a potent inducer of invadopodia via a specific signaling network.Synaptojanin 2 is a druggable mediator of metastasis and the gene is overexpressed and amplified in breast cancer.Phosphoramidate-based peptidomimetic inhibitors of membrane type-1 matrix metalloproteinaseSelective Inhibition of SIN3 Corepressor with Avermectins as a Novel Therapeutic Strategy in Triple-Negative Breast Cancer.MT1-MMP: Endosomal delivery drives breast cancer metastasis.The Trypanosome Exocyst: A Conserved Structure Revealing a New Role in Endocytosis.Cellular functions of WASP family proteins at a glance.Matrix rigidity differentially regulates invadopodia activity through ROCK1 and ROCK2.LIMK Regulates Tumor-Cell Invasion and Matrix Degradation Through Tyrosine Phosphorylation of MT1-MMP.Oncogenic BRAF-Mediated Melanoma Cell Invasion.Integrin endosomal signalling suppresses anoikis.RAB2A controls MT1-MMP endocytic and E-cadherin polarized Golgi trafficking to promote invasive breast cancer programs.Moesin and cortactin control actin-dependent multivesicular endosome biogenesis.The role of Tks adaptor proteins in invadopodia formation, growth and metastasis of melanoma.Digging a little deeper: the stages of invadopodium formation and maturation.Integrin traffic - the update.Role of cellular cytoskeleton in epithelial-mesenchymal transition process during cancer progression.2D and 3D Matrices to Study Linear Invadosome Formation and Activity.Function and regulation of the Arp2/3 complex during cell migration in diverse environments.p63/MT1-MMP axis is required for in situ to invasive transition in basal-like breast cancer.
P2860
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P2860
Endosomal WASH and exocyst complexes control exocytosis of MT1-MMP at invadopodia.
description
2013 nî lūn-bûn
@nan
2013 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Endosomal WASH and exocyst complexes control exocytosis of MT1-MMP at invadopodia
@nl
Endosomal WASH and exocyst complexes control exocytosis of MT1-MMP at invadopodia.
@ast
Endosomal WASH and exocyst complexes control exocytosis of MT1-MMP at invadopodia.
@en
Endosomal WASH and exocyst complexes control exocytosis of MT1-MMP at invadopodia.
@en-gb
type
label
Endosomal WASH and exocyst complexes control exocytosis of MT1-MMP at invadopodia
@nl
Endosomal WASH and exocyst complexes control exocytosis of MT1-MMP at invadopodia.
@ast
Endosomal WASH and exocyst complexes control exocytosis of MT1-MMP at invadopodia.
@en
Endosomal WASH and exocyst complexes control exocytosis of MT1-MMP at invadopodia.
@en-gb
prefLabel
Endosomal WASH and exocyst complexes control exocytosis of MT1-MMP at invadopodia
@nl
Endosomal WASH and exocyst complexes control exocytosis of MT1-MMP at invadopodia.
@ast
Endosomal WASH and exocyst complexes control exocytosis of MT1-MMP at invadopodia.
@en
Endosomal WASH and exocyst complexes control exocytosis of MT1-MMP at invadopodia.
@en-gb
P2093
P2860
P50
P921
P3181
P356
P1476
Endosomal WASH and exocyst complexes control exocytosis of MT1-MMP at invadopodia.
@en
P2093
Antonio Castro-Castro
Carine Rossé
Claire Desnos
Emilie Lagoutte
Etienne Formstecher
François Darchen
Marie Irondelle
Pedro Monteiro
P2860
P304
P3181
P356
10.1083/JCB.201306162
P407
P50
P577
2013-12-01T00:00:00Z