Human EDEM2, a novel homolog of family 47 glycosidases, is involved in ER-associated degradation of glycoproteins - Test2 - elhamkhani - TriplyDB

Human EDEM2, a novel homolog of family 47 glycosidases, is involved in ER-associated degradation of glycoproteins

Human EDEM2, a novel homolog of family 47 glycosidases, is involved in ER-associated degradation of glycoproteins

http://www.wikidata.org/entity/Q24313639

about

In vitro mannose trimming property of human ER α-1,2 mannosidase I Endoplasmic reticulum (ER) mannosidase I is compartmentalized and required for N-glycan trimming to Man5-6GlcNAc2 in glycoprotein ER-associated degradation EDEM2 initiates mammalian glycoprotein ERAD by catalyzing the first mannose trimming step Derlin-2 and Derlin-3 are regulated by the mammalian unfolded protein response and are required for ER-associated degradation Human OS-9, a lectin required for glycoprotein endoplasmic reticulum-associated degradation, recognizes mannose-trimmed N-glycans Human XTP3-B forms an endoplasmic reticulum quality control scaffold with the HRD1-SEL1L ubiquitin ligase complex and BiP ERdj4 and ERdj5 are required for endoplasmic reticulum-associated protein degradation of misfolded surfactant protein C The role of EDEM2 compared with EDEM1 in ricin transport from the endoplasmic reticulum to the cytosol EDEM is involved in retrotranslocation of ricin from the endoplasmic reticulum to the cytosol Histone deacetylase inhibitor (HDACi) suberoylanilide hydroxamic acid (SAHA)-mediated correction of α1-antitrypsin deficiency Getting in and out from calnexin/calreticulin cycles One step at a time: endoplasmic reticulum-associated degradation EDEM1 reveals a quality control vesicular transport pathway out of the endoplasmic reticulum not involving the COPII exit sites Protein folding and quality control in the ER Modulation of the unfolded protein response by the human hepatitis B virus The delicate balance between secreted protein folding and endoplasmic reticulum-associated degradation in human physiology Age and diet affect gene expression profile in canine skeletal muscle Modulation of activity by Arg407: structure of a fungal α-1,2-mannosidase in complex with a substrate analogue A Complex of Htm1 and the Oxidoreductase Pdi1 Accelerates Degradation of Misfolded Glycoproteins.Htm1 protein generates the N-glycan signal for glycoprotein degradation in the endoplasmic reticulum EDEM1 accelerates the trimming of alpha1,2-linked mannose on the C branch of N-glycans EDEM3, a soluble EDEM homolog, enhances glycoprotein endoplasmic reticulum-associated degradation and mannose trimming A Golgi-localized mannosidase (MAN1B1) plays a non-enzymatic gatekeeper role in protein biosynthetic quality control.EDEM2 and OS-9 are required for ER-associated degradation of non-glycosylated sonic hedgehog.Energetics of substrate binding and catalysis by class 1 (glycosylhydrolase family 47) alpha-mannosidases involved in N-glycan processing and endoplasmic reticulum quality control.Characterization of Schizosaccharomyces pombe ER alpha-mannosidase: a reevaluation of the role of the enzyme on ER-associated degradation Mixed-disulfide folding intermediates between thyroglobulin and endoplasmic reticulum resident oxidoreductases ERp57 and protein disulfide isomerase.Genome-wide association study identifies novel loci for plasma levels of protein C: the ARIC study.Forcible destruction of severely misfolded mammalian glycoproteins by the non-glycoprotein ERAD pathway Characterization of early EDEM1 protein maturation events and their functional implications.Role of Drosophila EDEMs in the degradation of the alpha-1-antitrypsin Z variant.Role of the endoplasmic reticulum-associated degradation (ERAD) pathway in degradation of hepatitis C virus envelope proteins and production of virus particles.Hydrophobicity of protein determinants influences the recognition of substrates by EDEM1 and EDEM2 in human cells.The evolution of N-glycan-dependent endoplasmic reticulum quality control factors for glycoprotein folding and degradation ERManI (Endoplasmic Reticulum Class I α-Mannosidase) Is Required for HIV-1 Envelope Glycoprotein Degradation via Endoplasmic Reticulum-associated Protein Degradation Pathway SEL1L, the homologue of yeast Hrd3p, is involved in protein dislocation from the mammalian ER.Versatility of the endoplasmic reticulum protein folding factory.Flagging and docking: dual roles for N-glycans in protein quality control and cellular proteostasis.mRNA N6-methyladenosine methylation of postnatal liver development in pig.Stimulation of N-linked glycosylation and lipid-linked oligosaccharide synthesis by stress responses in metazoan cells.

P2860

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P2860

Human EDEM2, a novel homolog of family 47 glycosidases, is involved in ER-associated degradation of glycoproteins

http://www.wikidata.org/entity/Q24313639

description

2005 nî lūn-bûn

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2005 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2005 թվականի ապրիլին հրատարակված գիտական հոդված

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2005年の論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

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2005年论文

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name

Human EDEM2, a novel homolog o ...... d degradation of glycoproteins

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Human EDEM2, a novel homolog o ...... d degradation of glycoproteins

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Human EDEM2, a novel homolog o ...... d degradation of glycoproteins

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Human EDEM2, a novel homolog o ...... d degradation of glycoproteins

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type

label

Human EDEM2, a novel homolog o ...... d degradation of glycoproteins

@ast

Human EDEM2, a novel homolog o ...... d degradation of glycoproteins

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Human EDEM2, a novel homolog o ...... d degradation of glycoproteins

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Human EDEM2, a novel homolog o ...... d degradation of glycoproteins

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prefLabel

Human EDEM2, a novel homolog o ...... d degradation of glycoproteins

@ast

Human EDEM2, a novel homolog o ...... d degradation of glycoproteins

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Human EDEM2, a novel homolog o ...... d degradation of glycoproteins

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Human EDEM2, a novel homolog o ...... d degradation of glycoproteins

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P1476

Human EDEM2, a novel homolog o ...... d degradation of glycoproteins

@en

P2093

Ann Davis

http://www.w3.org/2001/XMLSchema#string

Kelley W Moremen

http://www.w3.org/2001/XMLSchema#string

Khanita Karaveg

http://www.w3.org/2001/XMLSchema#string

Krista Diekman

http://www.w3.org/2001/XMLSchema#string

Richard N Sifers

http://www.w3.org/2001/XMLSchema#string

Steven W Mast

http://www.w3.org/2001/XMLSchema#string

P2860

Identification, expression, and characterization of a cDNA encoding human endoplasmic reticulum mannosidase I, the enzyme that catalyzes the first mannose trimming step in mammalian Asn-linked oligosaccharide biosynthesis

Role of EDEM in the release of misfolded glycoproteins from the calnexin cycle

Function of the p97-Ufd1-Npl4 complex in retrotranslocation from the ER to the cytosol: dual recognition of nonubiquitinated polypeptide segments and polyubiquitin chains

A novel ER alpha-mannosidase-like protein accelerates ER-associated degradation

Isolation, characterization, and expression of cDNAs encoding murine alpha-mannosidase II, a Golgi enzyme that controls conversion of high mannose to complex N-glycans

Basic local alignment search tool

A simple method for displaying the hydropathic character of a protein

Crystal structure of a class I α1,2-mannosidase involved in N-glycan processing and endoplasmic reticulum quality control

Structural basis for catalysis and inhibition of N-glycan processing class I alpha 1,2-mannosidases

Trichoderma reesei alpha-1,2-mannosidase: structural basis for the cleavage of four consecutive mannose residues

P304

421-36

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P31

scholarly article

P356

10.1093/GLYCOB/CWI014

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P407

P433

4

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P478

15

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P577

2005-04-01T00:00:00Z

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P5875

51369007

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P698

15537790

http://www.w3.org/2001/XMLSchema#string

P921

mannosyl-oligosaccharide 1,2-alpha-mannosidase activity

ER degradation enhancing alpha-mannosidase like protein 2