Human XTP3-B forms an endoplasmic reticulum quality control scaffold with the HRD1-SEL1L ubiquitin ligase complex and BiP - Test2 - elhamkhani - TriplyDB

Human XTP3-B forms an endoplasmic reticulum quality control scaffold with the HRD1-SEL1L ubiquitin ligase complex and BiP

Human XTP3-B forms an endoplasmic reticulum quality control scaffold with the HRD1-SEL1L ubiquitin ligase complex and BiP

http://www.wikidata.org/entity/Q24316328

about

A SEL1L mutation links a canine progressive early-onset cerebellar ataxia to the endoplasmic reticulum-associated protein degradation (ERAD) machinery Defining human ERAD networks through an integrative mapping strategy SEL1L protein critically determines the stability of the HRD1-SEL1L endoplasmic reticulum-associated degradation (ERAD) complex to optimize the degradation kinetics of ERAD substrates Malectin forms a complex with ribophorin I for enhanced association with misfolded glycoproteins Mannose trimming is required for delivery of a glycoprotein from EDEM1 to XTP3-B and to late endoplasmic reticulum-associated degradation steps A luminal flavoprotein in endoplasmic reticulum-associated degradation Human OS-9, a lectin required for glycoprotein endoplasmic reticulum-associated degradation, recognizes mannose-trimmed N-glycans EDEM1 recognition and delivery of misfolded proteins to the SEL1L-containing ERAD complex One step at a time: endoplasmic reticulum-associated degradation Protein folding and quality control in the ER Recent technical developments in the study of ER-associated degradation Road to ruin: targeting proteins for degradation in the endoplasmic reticulum The delicate balance between secreted protein folding and endoplasmic reticulum-associated degradation in human physiology How Polyomaviruses Exploit the ERAD Machinery to Cause Infection Five Questions (with their Answers) on ER-Associated Degradation Association of the SEL1L protein transmembrane domain with HRD1 ubiquitin ligase regulates ERAD-L Cyclosporine A-sensitive, cyclophilin B-dependent endoplasmic reticulum-associated degradation EDEM1 accelerates the trimming of alpha1,2-linked mannose on the C branch of N-glycans Deficiency of suppressor enhancer Lin12 1 like (SEL1L) in mice leads to systemic endoplasmic reticulum stress and embryonic lethality Derlin-1 deficiency is embryonic lethal, Derlin-3 deficiency appears normal, and Herp deficiency is intolerant to glucose load and ischemia in mice Live cell imaging of protein dislocation from the endoplasmic reticulum.EDEM2 and OS-9 are required for ER-associated degradation of non-glycosylated sonic hedgehog.SEL1L deficiency impairs growth and differentiation of pancreatic epithelial cells.Stringent requirement for HRD1, SEL1L, and OS-9/XTP3-B for disposal of ERAD-LS substrates.Modularity of the Hrd1 ERAD complex underlies its diverse client range.The endoplasmic reticulum-associated degradation of the epithelial sodium channel requires a unique complement of molecular chaperones.Novel thioredoxin-related transmembrane protein TMX4 has reductase activity.Identification of FBXL4 as a Metastasis Associated Gene in Prostate Cancer.Protein homeostasis of a metastable subproteome associated with Alzheimer's disease.OS-9 facilitates turnover of nonnative GRP94 marked by hyperglycosylation.Retroviral Rem protein requires processing by signal peptidase and retrotranslocation for nuclear function Quality and quantity control at the endoplasmic reticulum.The ubiquitin-selective segregase VCP/p97 orchestrates the response to DNA double-strand breaks.Deglycosylation-dependent fluorescent proteins provide unique tools for the study of ER-associated degradation.Forcible destruction of severely misfolded mammalian glycoproteins by the non-glycoprotein ERAD pathway Processing and turnover of the Hedgehog protein in the endoplasmic reticulum.Analysis of the sperm head protein profiles in fertile men: consistency across time in the levels of expression of heat shock proteins and peroxiredoxins.Characterization of early EDEM1 protein maturation events and their functional implications.Protein folding and quality control in the endoplasmic reticulum: Recent lessons from yeast and mammalian cell systems.Retroviral vectors elevate coexpressed protein levels in trans through cap-dependent translation.

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P2860

Human XTP3-B forms an endoplasmic reticulum quality control scaffold with the HRD1-SEL1L ubiquitin ligase complex and BiP

http://www.wikidata.org/entity/Q24316328

description

2008 nî lūn-bûn

@nan

2008 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

2008 թվականի հուլիսին հրատարակված գիտական հոդված

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2008年の論文

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年學術文章

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name

Human XTP3-B forms an endoplas ...... iquitin ligase complex and BiP

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Human XTP3-B forms an endoplas ...... iquitin ligase complex and BiP

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Human XTP3-B forms an endoplas ...... iquitin ligase complex and BiP

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Human XTP3-B forms an endoplas ...... iquitin ligase complex and BiP

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type

label

Human XTP3-B forms an endoplas ...... iquitin ligase complex and BiP

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Human XTP3-B forms an endoplas ...... iquitin ligase complex and BiP

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Human XTP3-B forms an endoplas ...... iquitin ligase complex and BiP

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Human XTP3-B forms an endoplas ...... iquitin ligase complex and BiP

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Human XTP3-B forms an endoplas ...... iquitin ligase complex and BiP

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Human XTP3-B forms an endoplas ...... iquitin ligase complex and BiP

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Human XTP3-B forms an endoplas ...... iquitin ligase complex and BiP

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Human XTP3-B forms an endoplas ...... iquitin ligase complex and BiP

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Human XTP3-B forms an endoplas ...... iquitin ligase complex and BiP

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P2093

Katsuya Okawa

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Kazuhiro Nagata

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Koji Nagasawa

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Nobuko Hosokawa

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P2860

The tumor autocrine motility factor receptor, gp78, is a ubiquitin protein ligase implicated in degradation from the endoplasmic reticulum

OS-9 interacts with hypoxia-inducible factor 1alpha and prolyl hydroxylases to promote oxygen-dependent degradation of HIF-1alpha

Human HRD1 is an E3 ubiquitin ligase involved in degradation of proteins from the endoplasmic reticulum

The MRH protein Erlectin is a member of the endoplasmic reticulum synexpression group and functions in N-glycan recognition

OS-9 and GRP94 deliver mutant alpha1-antitrypsin to the Hrd1-SEL1L ubiquitin ligase complex for ERAD

Human EDEM2, a novel homolog of family 47 glycosidases, is involved in ER-associated degradation of glycoproteins

A novel ER alpha-mannosidase-like protein accelerates ER-associated degradation

Multiprotein complexes that link dislocation, ubiquitination, and extraction of misfolded proteins from the endoplasmic reticulum membrane.

Synoviolin/Hrd1, an E3 ubiquitin ligase, as a novel pathogenic factor for arthropathy

A luminal surveillance complex that selects misfolded glycoproteins for ER-associated degradation.

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20914-24

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3843292

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10.1074/JBC.M709336200

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30

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P478

283

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Tatsuya Moriyama

P577

2008-07-25T00:00:00Z

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P698

18502753

http://www.w3.org/2001/XMLSchema#string

P921

OS9 endoplasmic reticulum lectin

endoplasmic reticulum

quality control

P932

3258950

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