Interaction of human apurinic endonuclease and DNA polymerase beta in the base excision repair pathway
about
Variant base excision repair proteins: contributors to genomic instability3-Methyladenine-DNA glycosylase (MPG protein) interacts with human RAD23 proteinsHMG2 interacts with the nucleosome assembly protein SET and is a target of the cytotoxic T-lymphocyte protease granzyme ASIRT1 deacetylates APE1 and regulates cellular base excision repairCleaving the oxidative repair protein Ape1 enhances cell death mediated by granzyme AThe genome of Melanoplus sanguinipes entomopoxvirusDomain specific interaction in the XRCC1-DNA polymerase beta complexModification of the human thymine-DNA glycosylase by ubiquitin-like proteins facilitates enzymatic turnoverXRCC1 coordinates the initial and late stages of DNA abasic site repair through protein-protein interactionsCoordination of steps in single-nucleotide base excision repair mediated by apurinic/apyrimidinic endonuclease 1 and DNA polymerase betaHuman base excision repair enzymes apurinic/apyrimidinic endonuclease1 (APE1), DNA polymerase beta and poly(ADP-ribose) polymerase 1: interplay between strand-displacement DNA synthesis and proofreading exonuclease activityThe accumulation of MMS-induced single strand breaks in G1 phase is recombinogenic in DNA polymerase beta defective mammalian cellsAPE1-dependent repair of DNA single-strand breaks containing 3'-end 8-oxoguanineDNA-bound structures and mutants reveal abasic DNA binding by APE1 and DNA repair coordination [corrected]Solution structure of an oligonucleotide containing an abasic site: evidence for an unusual deoxyribose conformationSynthesis, characterization and solution structure of tethered oligonucleotides containing an internal 3'-phosphoglycolate, 5'-phosphate gapped lesionDifferential expression of APE1 and APE2 in germinal centers promotes error-prone repair and A:T mutations during somatic hypermutationAn AP endonuclease 1-DNA polymerase beta complex: theoretical prediction of interacting surfacesComplexities of the DNA base excision repair pathway for repair of oxidative DNA damageDynamics of the interaction of human apurinic endonuclease (Ape1) with its substrate and productStimulation of human 8-oxoguanine-DNA glycosylase by AP-endonuclease: potential coordination of the initial steps in base excision repairThermodynamics of human DNA ligase I trimerization and association with DNA polymerase betaA quantitative model of human DNA base excision repair. I. Mechanistic insights.A novel action of human apurinic/apyrimidinic endonuclease: excision of L-configuration deoxyribonucleoside analogs from the 3' termini of DNA.Mechanism underlying replication protein a stimulation of DNA ligase I.3'-Azido-3'-deoxythymidine-resistant mutants of DNA polymerase beta identified by in vivo selection.Recent progress in the biology, chemistry and structural biology of DNA glycosylases.DNA polymerase β contains a functional nuclear localization signal at its N-terminus.DNA polymerase β uses its lyase domain in a processive search for DNA damage.Functional characterization of Ape1 variants identified in the human populationDNA breaks and chromosomal aberrations arise when replication meets base excision repair.Overexpression of enzymes that repair endogenous damage to DNA.Base excision repair initiation revealed by crystal structures and binding kinetics of human uracil-DNA glycosylase with DNA.Reactive oxygen radicals in signaling and damage in the ischemic brain.Activation of APE/Ref-1 redox activity is mediated by reactive oxygen species and PKC phosphorylation.APE1/Ref-1 as an emerging therapeutic target for various human diseases: phytochemical modulation of its functionsPol β associated complex and base excision repair factors in mouse fibroblasts.Investigating the structural impacts of I64T and P311S mutations in APE1-DNA complex: a molecular dynamics approach.DNA repair deficiency in neurodegeneration.Interdependent phosphorylation within the kinase domain T-loop Regulates CHK2 activity
P2860
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P2860
Interaction of human apurinic endonuclease and DNA polymerase beta in the base excision repair pathway
description
1997 nî lūn-bûn
@nan
1997 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Interaction of human apurinic ...... e base excision repair pathway
@ast
Interaction of human apurinic ...... e base excision repair pathway
@en
Interaction of human apurinic ...... e base excision repair pathway
@en-gb
Interaction of human apurinic ...... e base excision repair pathway
@nl
type
label
Interaction of human apurinic ...... e base excision repair pathway
@ast
Interaction of human apurinic ...... e base excision repair pathway
@en
Interaction of human apurinic ...... e base excision repair pathway
@en-gb
Interaction of human apurinic ...... e base excision repair pathway
@nl
prefLabel
Interaction of human apurinic ...... e base excision repair pathway
@ast
Interaction of human apurinic ...... e base excision repair pathway
@en
Interaction of human apurinic ...... e base excision repair pathway
@en-gb
Interaction of human apurinic ...... e base excision repair pathway
@nl
P2093
P2860
P356
P1476
Interaction of human apurinic ...... e base excision repair pathway
@en
P2093
P2860
P304
P356
10.1073/PNAS.94.14.7166
P407
P577
1997-07-08T00:00:00Z