Abi-2, a novel SH3-containing protein interacts with the c-Abl tyrosine kinase and modulates c-Abl transforming activity
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Inclusion of Scar/WAVE3 in a similar complex to Scar/WAVE1 and 2Functional interaction between c-Abl and the p21-activated protein kinase gamma-PAKABL tyrosine kinases: evolution of function, regulation, and specificityAbi-1 forms an epidermal growth factor-inducible complex with Cbl: role in receptor endocytosisStructure and control of the actin regulatory WAVE complexNESH (Abi-3) is present in the Abi/WAVE complex but does not promote c-Abl-mediated phosphorylationIdentification of a candidate human spectrin Src homology 3 domain-binding protein suggests a general mechanism of association of tyrosine kinases with the spectrin-based membrane skeletonRegulation of DNA damage-induced apoptosis by the c-Abl tyrosine kinaseAllosteric inhibition of the nonMyristoylated c-Abl tyrosine kinase by phosphopeptides derived from Abi1/Hssh3bp1Co-expression with BCR induces activation of the FES tyrosine kinase and phosphorylation of specific N-terminal BCR tyrosine residuesAhi-1, a novel gene encoding a modular protein with WD40-repeat and SH3 domains, is targeted by the Ahi-1 and Mis-2 provirus integrationsAbl interactor 1 binds to sos and inhibits epidermal growth factor- and v-Abl-induced activation of extracellular signal-regulated kinasesType IV secretion in the obligatory intracellular bacterium Anaplasma phagocytophilumThe PAG gene product, a stress-induced protein with antioxidant properties, is an Abl SH3-binding protein and a physiological inhibitor of c-Abl tyrosine kinase activityc-Abl-induced apoptosis, but not cell cycle arrest, requires mitogen-activated protein kinase kinase 6 activationThe amphiphysin-like protein 1 (ALP1) interacts functionally with the cABL tyrosine kinase and may play a role in cytoskeletal regulationBcr-Abl induces abnormal cytoskeleton remodeling, beta1 integrin clustering and increased cell adhesion to fibronectin through the Abl interactor 1 pathwayDissecting Nck/Dock signaling pathways in Drosophila visual system.Phosphoregulation of the WAVE regulatory complex and signal integrationAbl interactor 1 promotes tyrosine 296 phosphorylation of mammalian enabled (Mena) by c-Abl kinaseMultiple signaling interactions of Abl and Arg kinases with the EphB2 receptorRegulation of Cbl phosphorylation by the Abl tyrosine kinase and the Nck SH2/SH3 adaptorAbi1 is essential for the formation and activation of a WAVE2 signalling complexCharacterization of the EMS1 gene and its product, human CortactinUnc119 protects from Shigella infection by inhibiting the Abl family kinasesIdentification of sirm, a novel insulin-regulated SH3 binding protein that associates with Grb-2 and FYNArg interacts with cortactin to promote adhesion-dependent cell edge protrusionAHI-1 interacts with BCR-ABL and modulates BCR-ABL transforming activity and imatinib response of CML stem/progenitor cellsABI2-deficient mice exhibit defective cell migration, aberrant dendritic spine morphogenesis, and deficits in learning and memorySH3 domains: modules of protein-protein interactions.The NESH/Abi-3-based WAVE2 complex is functionally distinct from the Abi-1-based WAVE2 complex.Two-state dynamics of the SH3-SH2 tandem of Abl kinase and the allosteric role of the N-capIntramolecular dynamics within the N-Cap-SH3-SH2 regulatory unit of the c-Abl tyrosine kinase reveal targeting to the cellular membraneC3G forms complexes with Bcr-Abl and p38α MAPK at the focal adhesions in chronic myeloid leukemia cells: implication in the regulation of leukemic cell adhesion.Abelson interactor-1 (ABI-1) interacts with MRL adaptor protein MIG-10 and is required in guided cell migrations and process outgrowth in C. elegans.Functional mechanisms and roles of adaptor proteins in abl-regulated cytoskeletal actin dynamics.Tyrosine phosphorylation in the SH3 domain disrupts negative regulatory interactions within the c-Abl kinase core.A crucial role in cell spreading for the interaction of Abl PxxP motifs with Crk and Nck adaptors.Mitotic phosphorylation rescues Abl from F-actin-mediated inhibition.Abl interactor 1 (Abi-1) wave-binding and SNARE domains regulate its nucleocytoplasmic shuttling, lamellipodium localization, and wave-1 levels.
P2860
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P2860
Abi-2, a novel SH3-containing protein interacts with the c-Abl tyrosine kinase and modulates c-Abl transforming activity
description
1995 nî lūn-bûn
@nan
1995 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
Abi-2, a novel SH3-containing ...... es c-Abl transforming activity
@ast
Abi-2, a novel SH3-containing ...... es c-Abl transforming activity
@en
Abi-2, a novel SH3-containing ...... es c-Abl transforming activity
@en-gb
Abi-2, a novel SH3-containing ...... es c-Abl transforming activity
@nl
type
label
Abi-2, a novel SH3-containing ...... es c-Abl transforming activity
@ast
Abi-2, a novel SH3-containing ...... es c-Abl transforming activity
@en
Abi-2, a novel SH3-containing ...... es c-Abl transforming activity
@en-gb
Abi-2, a novel SH3-containing ...... es c-Abl transforming activity
@nl
prefLabel
Abi-2, a novel SH3-containing ...... es c-Abl transforming activity
@ast
Abi-2, a novel SH3-containing ...... es c-Abl transforming activity
@en
Abi-2, a novel SH3-containing ...... es c-Abl transforming activity
@en-gb
Abi-2, a novel SH3-containing ...... es c-Abl transforming activity
@nl
P921
P356
P1433
P1476
Abi-2, a novel SH3-containing ...... es c-Abl transforming activity
@en
P2093
P304
P356
10.1101/GAD.9.21.2569
P407
P577
1995-11-01T00:00:00Z