A crucial role in cell spreading for the interaction of Abl PxxP motifs with Crk and Nck adaptors.
about
Identification and functional analysis of a new phosphorylation site (Y398) in the SH3 domain of Abi-1ABL tyrosine kinases: evolution of function, regulation, and specificityRegulation of cell migration and morphogenesis by Abl-family kinases: emerging mechanisms and physiological contextsIntegration of linear and dendritic actin nucleation in Nck-induced actin comets.Arg interacts with cortactin to promote adhesion-dependent cell edge protrusionAbl family tyrosine kinases are essential for basement membrane integrity and cortical lamination in the cerebellumLarge-Scale Screening of Preferred Interactions of Human Src Homology-3 (SH3) Domains Using Native Target Proteins as Affinity LigandsAbelson kinase acts as a robust, multifunctional scaffold in regulating embryonic morphogenesis.Binding Mechanism of the N-Terminal SH3 Domain of CrkII and Proline-Rich Motifs in cAblConserved interdomain linker promotes phase separation of the multivalent adaptor protein Nck.Iterative tyrosine phosphorylation controls non-canonical domain utilization in Crk.Interaction of crk with Myosin-1c participates in fibronectin-induced cell spreading.Two-state dynamics of the SH3-SH2 tandem of Abl kinase and the allosteric role of the N-capDomain cooperativity in multidomain proteins: what can we learn from molecular alignment in anisotropic media?Distinct roles for Crk adaptor isoforms in actin reorganization induced by extracellular signalsNck2 promotes human melanoma cell proliferation, migration and invasion in vitro and primary melanoma-derived tumor growth in vivoPhase transitions of multivalent proteins can promote clustering of membrane receptorsSrc activates Abl to augment Robo1 expression in order to promote tumor cell migration.Crk adaptors negatively regulate actin polymerization in pedestals formed by enteropathogenic Escherichia coli (EPEC) by binding to Tir effector.Crk1/2-dependent signaling is necessary for podocyte foot process spreading in mouse models of glomerular disease.Distinct functional domains of the Abelson tyrosine kinase control axon guidance responses to Netrin and Slit to regulate the assembly of neural circuits.c-Abl-dependent molecular circuitry involving Smad5 and phosphatidylinositol 3-kinase regulates bone morphogenetic protein-2-induced osteogenesis.The ubiquitin-proteasome system regulates focal adhesions at the leading edge of migrating cells.Ableson kinases negatively regulate invadopodia function and invasion in head and neck squamous cell carcinoma by inhibiting an HB-EGF autocrine loop.Integration of signaling and cytoskeletal remodeling by Nck in directional cell migrationCrk1/2 and CrkL form a hetero-oligomer and functionally complement each other during podocyte morphogenesis.Crk and CrkL adaptor proteins: networks for physiological and pathological signalingThe Abl and Arg non-receptor tyrosine kinases regulate different zones of stress fiber, focal adhesion, and contractile network localization in spreading fibroblasts.Long disordered regions of the C-terminal domain of Abelson tyrosine kinase have specific and additive functions in regulation and axon localization.Crk adaptor protein promotes PD-L1 expression, EMT and immune evasion in a murine model of triple-negative breast cancer.Optogenetic activation of EphB2 receptor in dendrites induced actin polymerization by activating Arg kinase.Role of Non Receptor Tyrosine Kinases in Hematological Malignances and its Targeting by Natural Products.
P2860
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P2860
A crucial role in cell spreading for the interaction of Abl PxxP motifs with Crk and Nck adaptors.
description
2008 nî lūn-bûn
@nan
2008 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
A crucial role in cell spreadi ...... ifs with Crk and Nck adaptors.
@ast
A crucial role in cell spreadi ...... ifs with Crk and Nck adaptors.
@en
type
label
A crucial role in cell spreadi ...... ifs with Crk and Nck adaptors.
@ast
A crucial role in cell spreadi ...... ifs with Crk and Nck adaptors.
@en
prefLabel
A crucial role in cell spreadi ...... ifs with Crk and Nck adaptors.
@ast
A crucial role in cell spreadi ...... ifs with Crk and Nck adaptors.
@en
P2093
P2860
P356
P1476
A crucial role in cell spreadi ...... ifs with Crk and Nck adaptors.
@en
P2093
Bruce J Mayer
Gonzalo M Rivera
Susumu Antoku
P2860
P304
P356
10.1242/JCS.031575
P407
P577
2008-09-01T00:00:00Z