Lysosomal hydrolases of different classes are abnormally distributed in brains of patients with Alzheimer disease - Test2 - elhamkhani - TriplyDB

Lysosomal hydrolases of different classes are abnormally distributed in brains of patients with Alzheimer disease

Lysosomal hydrolases of different classes are abnormally distributed in brains of patients with Alzheimer disease

http://www.wikidata.org/entity/Q24315025

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Reduced glucocerebrosidase is associated with increased α-synuclein in sporadic Parkinson's disease Lysosomal processing of amyloid precursor protein to A beta peptides: a distinct role for cathepsin S Mild cognitive impairment: pathology and mechanisms.Tau fragmentation, aggregation and clearance: the dual role of lysosomal processing Dual roles for autophagy: degradation and secretion of Alzheimer's disease Aβ peptide The cysteine protease inhibitor, E64d, reduces brain amyloid-β and improves memory deficits in Alzheimer's disease animal models by inhibiting cathepsin B, but not BACE1, β-secretase activity Cathepsin D--many functions of one aspartic protease Cysteine protease inhibitors effectively reduce in vivo levels of brain beta-amyloid related to Alzheimer's disease Arf6 controls beta-amyloid production by regulating macropinocytosis of the Amyloid Precursor Protein to lysosomes The human amyloid-beta precursor protein770 mutation V717F generates peptides longer than amyloid-beta-(40-42) and flocculent amyloid aggregates.Comparative proteomics of cerebrospinal fluid in neuropathologically-confirmed Alzheimer's disease and non-demented elderly subjects.Lysosomal NEU1 deficiency affects amyloid precursor protein levels and amyloid-β secretion via deregulated lysosomal exocytosis Upregulation of the genes encoding lysosomal hydrolases, a perforin-like protein, and peroxidases in the brains of mice affected with an experimental prion disease Oxidative stress and autophagy in the regulation of lysosome-dependent neuron death.Cathepsin deficiency as a model for neuronal ceroid lipofuscinoses.Ubiquitin, lysosomes, and neurodegenerative diseases.Myelin basic protein associates with AβPP, Aβ1-42, and amyloid plaques in cortex of Alzheimer's disease brain Massive accumulation of luminal protease-deficient axonal lysosomes at Alzheimer's disease amyloid plaques Cholesterol accumulation is associated with lysosomal dysfunction and autophagic stress in Npc1 -/- mouse brain Amyloid deposition and advanced age fails to induce Alzheimer's type progression in a double knock-in mouse model The ubiquitin-proteasome system and the autophagic-lysosomal system in Alzheimer disease.Widespread activation of calcium-activated neutral proteinase (calpain) in the brain in Alzheimer disease: a potential molecular basis for neuronal degeneration The Role of Oxidized Cholesterol in Diabetes-Induced Lysosomal Dysfunction in the Brain.Delta-secretase cleaves amyloid precursor protein and regulates the pathogenesis in Alzheimer's disease Trafficking of cell surface beta-amyloid precursor protein: retrograde and transcytotic transport in cultured neurons.Single cell gene expression profiling in Alzheimer's disease.Autophagic and lysosomal defects in human tauopathies: analysis of post-mortem brain from patients with familial Alzheimer disease, corticobasal degeneration and progressive supranuclear palsy.Neuronal apoptosis and autophagy cross talk in aging PS/APP mice, a model of Alzheimer's disease.The proteasome: a macromolecular assembly designed to confine proteolysis to a nanocompartment.Activation of asparaginyl endopeptidase leads to Tau hyperphosphorylation in Alzheimer disease.Rapid induction of intraneuronal neurofibrillary tangles in apolipoprotein E-deficient mice.pdf1, a palmitoyl protein thioesterase 1 Ortholog in Schizosaccharomyces pombe: a yeast model of infantile Batten disease.Perturbation of neuronal cobalamin transport by lysosomal enzyme inhibition Protein homeostasis, aging and Alzheimer's disease.Protein truncation as a common denominator of human neurodegenerative foldopathies.Cysteine cathepsins in neurological disorders.The Role of Cathepsin D in the Pathogenesis of Human Neurodegenerative Disorders.Endo-lysosomal and autophagic dysfunction: a driving factor in Alzheimer's disease?APP and APLP1 are degraded through autophagy in response to proteasome inhibition in neuronal cells.The Alzheimer's β-secretase BACE1 localizes to normal presynaptic terminals and to dystrophic presynaptic terminals surrounding amyloid plaques.

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Lysosomal hydrolases of different classes are abnormally distributed in brains of patients with Alzheimer disease

http://www.wikidata.org/entity/Q24315025

description

1991 nî lūn-bûn

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1991 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

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1991 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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1991年の論文

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1991年論文

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1991年論文

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1991年論文

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1991年論文

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1991年論文

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1991年论文

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name

Lysosomal hydrolases of differ ...... atients with Alzheimer disease

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Lysosomal hydrolases of differ ...... atients with Alzheimer disease

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Lysosomal hydrolases of differ ...... atients with Alzheimer disease

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Lysosomal hydrolases of differ ...... atients with Alzheimer disease

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Lysosomal hydrolases of differ ...... atients with Alzheimer disease

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Lysosomal hydrolases of differ ...... atients with Alzheimer disease

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Lysosomal hydrolases of differ ...... atients with Alzheimer disease

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Lysosomal hydrolases of differ ...... atients with Alzheimer disease

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Lysosomal hydrolases of differ ...... atients with Alzheimer disease

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Lysosomal hydrolases of differ ...... atients with Alzheimer disease

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Lysosomal hydrolases of differ ...... atients with Alzheimer disease

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PNAS.88.24.10998

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Proceedings of the National Academy of Sciences of the United States of America

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Lysosomal hydrolases of differ ...... atients with Alzheimer disease

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A M Cataldo

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E Kominami

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P A Paskevich

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R A Nixon

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P2860

Neurotrophic and neurotoxic effects of amyloid beta protein: reversal by tachykinin neuropeptides

Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: a comparison between ABC and unlabeled antibody (PAP) procedures

The use of lead citrate at high pH as an electron-opaque stain in electron microscopy

Microtubule-associated protein tau (tau) is a major antigenic component of paired helical filaments in Alzheimer disease

Enzymatically active lysosomal proteases are associated with amyloid deposits in Alzheimer brain

Identification, transmembrane orientation and biogenesis of the amyloid A4 precursor of Alzheimer's disease

Proteolytic cleavage of the Alzheimer's disease amyloid A4 precursor protein.

Structures and functions of lysosomal thiol proteinases and their endogenous inhibitor.

A SIMPLIFIED LEAD CITRATE STAIN FOR USE IN ELECTRON MICROSCOPY.

Cleavage of amyloid beta peptide during constitutive processing of its precursor.

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1837142

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Alzheimer's disease

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53060

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