Structure of a conserved dimerization domain within the F-box protein Fbxo7 and the PI31 proteasome inhibitor
about
The Parkinson's disease-linked proteins Fbxo7 and Parkin interact to mediate mitophagyLinking F-box protein 7 and parkin to neuronal degeneration in Parkinson's disease (PD)Structure of the FP domain of Fbxo7 reveals a novel mode of protein-protein interactionThe FP domains of PI31 and Fbxo7 have the same protein fold but very different modes of protein-protein interactionLoss of nuclear activity of the FBXO7 protein in patients with parkinsonian-pyramidal syndrome (PARK15)A Competitive binding mechanism between Skp1 and exportin 1 (CRM1) controls the localization of a subset of F-box proteinsFBXO7 Y52C polymorphism as a potential protective factor in Parkinson's diseaseEvolution of proteasome regulators in eukaryotesIsolation, identification and expression analysis of salt-induced genes in Suaeda maritima, a natural halophyte, using PCR-based suppression subtractive hybridization.Molecular and cellular roles of PI31 (PSMF1) protein in regulation of proteasome function.Novel ATP13A2 (PARK9) homozygous mutation in a family with marked phenotype variabilityIdentification of residues in the N-terminal PAS domains important for dimerization of Arnt and AhR.A conserved F box regulatory complex controls proteasome activity in Drosophila.Deciphering preferential interactions within supramolecular protein complexes: the proteasome case.An evolutionary analysis of antigen processing and presentation across different timescales reveals pervasive selection.The F-box protein FBXO7 positively regulates bone morphogenetic protein-mediated signaling through Lys-63-specific ubiquitination of neurotrophin receptor-interacting MAGE (NRAGE).The proteasome: overview of structure and functions.Expression, purification and crystallization of the FP domain of the human F-box protein Fbxo7Beyond ubiquitination: the atypical functions of Fbxo7 and other F-box proteins.Gsk3β and Tomm20 are substrates of the SCFFbxo7/PARK15 ubiquitin ligase associated with Parkinson's disease.The role of the proteasome in heart diseaseHarnessing proteasome dynamics and allostery in drug design.Ubiquitin and Parkinson's disease through the looking glass of genetics.A novel F-box protein is required for caspase activation during cellular remodeling in Drosophila.Structure of Spo0M, a sporulation-control protein from Bacillus subtilis.Loss of FBXO7 (PARK15) results in reduced proteasome activity and models a parkinsonism-like phenotype in miceN-terminal α7 deletion of the proteasome 20S core particle substitutes for yeast PI31 function.Characterization of the porcine FBX07 gene: the first step towards generation of a pig model for Parkinsonian pyramidal syndrome.Mechanistic contributions of FBXO7 to Parkinson disease.The FBXO7 homologue nutcracker and binding partner PI31 in Drosophila melanogaster models of Parkinson's disease.
P2860
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P2860
Structure of a conserved dimerization domain within the F-box protein Fbxo7 and the PI31 proteasome inhibitor
description
2008 nî lūn-bûn
@nan
2008 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Structure of a conserved dimer ...... the PI31 proteasome inhibitor
@ast
Structure of a conserved dimer ...... the PI31 proteasome inhibitor
@en
Structure of a conserved dimer ...... the PI31 proteasome inhibitor
@en-gb
Structure of a conserved dimer ...... the PI31 proteasome inhibitor
@nl
type
label
Structure of a conserved dimer ...... the PI31 proteasome inhibitor
@ast
Structure of a conserved dimer ...... the PI31 proteasome inhibitor
@en
Structure of a conserved dimer ...... the PI31 proteasome inhibitor
@en-gb
Structure of a conserved dimer ...... the PI31 proteasome inhibitor
@nl
prefLabel
Structure of a conserved dimer ...... the PI31 proteasome inhibitor
@ast
Structure of a conserved dimer ...... the PI31 proteasome inhibitor
@en
Structure of a conserved dimer ...... the PI31 proteasome inhibitor
@en-gb
Structure of a conserved dimer ...... the PI31 proteasome inhibitor
@nl
P2093
P2860
P921
P3181
P356
P1476
Structure of a conserved dimer ...... the PI31 proteasome inhibitor
@en
P2093
El Kahina Meziane
Judith Murray-Rust
Mikhail Lomonosov
Neil Q McDonald
Phillip P Knowles
P2860
P304
22325-22335
P3181
P356
10.1074/JBC.M709900200
P407
P577
2008-05-20T00:00:00Z