Fbx7 functions in the SCF complex regulating Cdk1-cyclin B-phosphorylated hepatoma up-regulated protein (HURP) proteolysis by a proline-rich region
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Phosphorylation and stabilization of HURP by Aurora-A: implication of HURP as a transforming target of Aurora-AStructure of a conserved dimerization domain within the F-box protein Fbxo7 and the PI31 proteasome inhibitorThe Parkinson's disease-linked proteins Fbxo7 and Parkin interact to mediate mitophagyHURP controls spindle dynamics to promote proper interkinetochore tension and efficient kinetochore capture.Linking F-box protein 7 and parkin to neuronal degeneration in Parkinson's disease (PD)Genetically engineered mouse models for functional studies of SKP1-CUL1-F-box-protein (SCF) E3 ubiquitin ligasesStructure of the FP domain of Fbxo7 reveals a novel mode of protein-protein interactionInhibition of apoptosis by oncogenic hepatitis B virus X protein: Implications for the treatment of hepatocellular carcinomaLoss of nuclear activity of the FBXO7 protein in patients with parkinsonian-pyramidal syndrome (PARK15)A Competitive binding mechanism between Skp1 and exportin 1 (CRM1) controls the localization of a subset of F-box proteinsF-box protein 7 mutations promote protein aggregation in mitochondria and inhibit mitophagyFBXO7 Y52C polymorphism as a potential protective factor in Parkinson's diseaseCDK-1 Inhibition in G2 Stabilizes Kinetochore-Microtubules in the following MitosisDeregulation of F-box proteins and its consequence on cancer development, progression and metastasis.A translational regulator, PUM2, promotes both protein stability and kinase activity of Aurora-AGene expression profile of empirically delineated classes of unexplained chronic fatigue.VEGFA upregulates FLJ10540 and modulates migration and invasion of lung cancer via PI3K/AKT pathway.ISWI is a RanGTP-dependent MAP required for chromosome segregationTranscriptomic profiling of purified patient-derived dopamine neurons identifies convergent perturbations and therapeutics for Parkinson's disease.Expression of Fbxo7 in haematopoietic progenitor cells cooperates with p53 loss to promote lymphomagenesis.HURP expression-assisted risk scores identify prognosis distinguishable subgroups in early stage liver cancer.Identification of F-box only protein 7 as a negative regulator of NF-kappaB signalling.Oncogenic function of SCCRO5/DCUN1D5 requires its Neddylation E3 activity and nuclear localization.Novel ATP13A2 (PARK9) homozygous mutation in a family with marked phenotype variabilityRoles of F-box proteins in cancerThe F-box protein FBXO7 positively regulates bone morphogenetic protein-mediated signaling through Lys-63-specific ubiquitination of neurotrophin receptor-interacting MAGE (NRAGE).Quantification of ortholog losses in insects and vertebrates.Aurora A regulates the activity of HURP by controlling the accessibility of its microtubule-binding domain.Ubiquitination-mediated degradation of cell cycle-related proteins by F-box proteinsGenome-wide linkage analysis of a Parkinsonian-pyramidal syndrome pedigree by 500 K SNP arrays.Overexpression of beta2-microglobulin is associated with poor survival in patients with oral cavity squamous cell carcinoma and contributes to oral cancer cell migration and invasion.Expression, purification and crystallization of the FP domain of the human F-box protein Fbxo7mars and tousled-like kinase act in parallel to ensure chromosome fidelity in Drosophila.Beyond ubiquitination: the atypical functions of Fbxo7 and other F-box proteins.Secretory granule to the nucleus: role of a multiply phosphorylated intrinsically unstructured domain.Signaling from the secretory granule to the nucleus.Gsk3β and Tomm20 are substrates of the SCFFbxo7/PARK15 ubiquitin ligase associated with Parkinson's disease.Opposing effects on the cell cycle of T lymphocytes by Fbxo7 via Cdk6 and p27Recent advances in SCF ubiquitin ligase complex: Clinical implicationsUbiquitin and Parkinson's disease through the looking glass of genetics.
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P2860
Fbx7 functions in the SCF complex regulating Cdk1-cyclin B-phosphorylated hepatoma up-regulated protein (HURP) proteolysis by a proline-rich region
description
2004 nî lūn-bûn
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2004 թուականի Յուլիսին հրատարակուած գիտական յօդուած
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2004 թվականի հուլիսին հրատարակված գիտական հոդված
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2004年の論文
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2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
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2004年论文
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name
Fbx7 functions in the SCF comp ...... lysis by a proline-rich region
@ast
Fbx7 functions in the SCF comp ...... lysis by a proline-rich region
@en
Fbx7 functions in the SCF comp ...... lysis by a proline-rich region
@en-gb
Fbx7 functions in the SCF comp ...... lysis by a proline-rich region
@nl
type
label
Fbx7 functions in the SCF comp ...... lysis by a proline-rich region
@ast
Fbx7 functions in the SCF comp ...... lysis by a proline-rich region
@en
Fbx7 functions in the SCF comp ...... lysis by a proline-rich region
@en-gb
Fbx7 functions in the SCF comp ...... lysis by a proline-rich region
@nl
prefLabel
Fbx7 functions in the SCF comp ...... lysis by a proline-rich region
@ast
Fbx7 functions in the SCF comp ...... lysis by a proline-rich region
@en
Fbx7 functions in the SCF comp ...... lysis by a proline-rich region
@en-gb
Fbx7 functions in the SCF comp ...... lysis by a proline-rich region
@nl
P2093
P2860
P921
P3181
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P1476
Fbx7 functions in the SCF comp ...... lysis by a proline-rich region
@en
P2093
Chang-Tze R Yu
Chi-Ying F Huang
Jung-Mao Hsu
Yuan-Chii G Lee
P2860
P304
P3181
P356
10.1074/JBC.M404950200
P407
P577
2004-07-30T00:00:00Z