Increased alpha-synuclein aggregation following limited cleavage by certain matrix metalloproteinases
about
DJ-1 cleavage by matrix metalloproteinase 3 mediates oxidative stress-induced dopaminergic cell deathFriends or Foes: Matrix Metalloproteinases and Their Multifaceted Roles in Neurodegenerative DiseasesThe potential of pathological protein fragmentation in blood-based biomarker development for dementia - with emphasis on Alzheimer's diseaseFunction and dysfunction of α-synuclein: probing conformational changes and aggregation by single molecule fluorescenceRoles of tau protein in health and disease.The Cleavage Effect of Mesenchymal Stem Cell and Its Derived Matrix Metalloproteinase-2 on Extracellular α-Synuclein Aggregates in Parkinsonian ModelsReducing C-terminal-truncated alpha-synuclein by immunotherapy attenuates neurodegeneration and propagation in Parkinson's disease-like models.Identification of novel α-synuclein isoforms in human brain tissue by using an online nanoLC-ESI-FTICR-MS methodAccumulation of α-synuclein in dementia with Lewy bodies is associated with decline in the α-synuclein-degrading enzymes kallikrein-6 and calpain-1.Matrix metalloproteinase-3 causes dopaminergic neuronal death through Nox1-regenerated oxidative stressRole of matrix metalloproteinase 3-mediated alpha-synuclein cleavage in dopaminergic cell death.Proteolytic cleavage of extracellular α-synuclein by plasmin: implications for Parkinson disease.Combination therapies: The next logical Step for the treatment of synucleinopathies?Associations of Matrix Metalloproteinase-9 and Tissue Inhibitory Factor-1 Polymorphisms With Parkinson Disease in Taiwan.Axonopathy in an α-synuclein transgenic model of Lewy body disease is associated with extensive accumulation of C-terminal-truncated α-synucleinPMEL: a pigment cell-specific model for functional amyloid formationKLK6 proteolysis is implicated in the turnover and uptake of extracellular alpha-synuclein species.Intracellular substrate cleavage: a novel dimension in the biochemistry, biology and pathology of matrix metalloproteinases.Cerebral microvascular endothelium and the pathogenesis of neurodegenerative diseases.α-Synuclein and protein degradation systems: a reciprocal relationship.Parkinson's disease: from genetics to treatments.Protein Transmission, Seeding and Degradation: Key Steps for α-Synuclein Prion-Like PropagationPhysiological functions and clinical implications of the N-end rule pathway.Cell Biology and Pathophysiology of α-Synuclein.Synergistic influence of phosphorylation and metal ions on tau oligomer formation and coaggregation with α-synuclein at the single molecule level.Neurodegeneration-associated protein fragments as short-lived substrates of the N-end rule pathway.Changes in matrix metalloprotease activity and progranulin levels may contribute to the pathophysiological function of mutant leucine-rich repeat kinase 2.
P2860
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P2860
Increased alpha-synuclein aggregation following limited cleavage by certain matrix metalloproteinases
description
2009 nî lūn-bûn
@nan
2009 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Increased alpha-synuclein aggr ...... tain matrix metalloproteinases
@ast
Increased alpha-synuclein aggr ...... tain matrix metalloproteinases
@en
Increased alpha-synuclein aggr ...... tain matrix metalloproteinases
@en-gb
Increased alpha-synuclein aggr ...... tain matrix metalloproteinases
@nl
type
label
Increased alpha-synuclein aggr ...... tain matrix metalloproteinases
@ast
Increased alpha-synuclein aggr ...... tain matrix metalloproteinases
@en
Increased alpha-synuclein aggr ...... tain matrix metalloproteinases
@en-gb
Increased alpha-synuclein aggr ...... tain matrix metalloproteinases
@nl
prefLabel
Increased alpha-synuclein aggr ...... tain matrix metalloproteinases
@ast
Increased alpha-synuclein aggr ...... tain matrix metalloproteinases
@en
Increased alpha-synuclein aggr ...... tain matrix metalloproteinases
@en-gb
Increased alpha-synuclein aggr ...... tain matrix metalloproteinases
@nl
P2093
P921
P1476
Increased alpha-synuclein aggr ...... tain matrix metalloproteinases
@en
P2093
Georg Nübling
Hans Kretzschmar
Kai Boetzel
Lars Israel
Stefan Lorenzl
Tobias Högen
P304
P356
10.1016/J.EXPNEUROL.2008.10.010
P407
P577
2008-10-31T00:00:00Z