Accumulation of α-synuclein in dementia with Lewy bodies is associated with decline in the α-synuclein-degrading enzymes kallikrein-6 and calpain-1.
about
A brain-targeted, modified neurosin (kallikrein-6) reduces α-synuclein accumulation in a mouse model of multiple system atrophy.Aggregated Alpha-Synuclein Transfer Efficiently between Cultured Human Neuron-Like Cells and Localize to LysosomesLRRC31 is induced by IL-13 and regulates kallikrein expression and barrier function in the esophageal epithelium.KLK6 proteolysis is implicated in the turnover and uptake of extracellular alpha-synuclein species.Endothelin-converting enzymes degrade α-synuclein and are reduced in dementia with Lewy bodies.Alpha-synuclein overexpression in the olfactory bulb initiates prodromal symptoms and pathology of Parkinson's disease
P2860
Accumulation of α-synuclein in dementia with Lewy bodies is associated with decline in the α-synuclein-degrading enzymes kallikrein-6 and calpain-1.
description
2014 nî lūn-bûn
@nan
2014 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Accumulation of α-synuclein in ...... es kallikrein-6 and calpain-1.
@ast
Accumulation of α-synuclein in ...... es kallikrein-6 and calpain-1.
@en
Accumulation of α-synuclein in ...... es kallikrein-6 and calpain-1.
@nl
type
label
Accumulation of α-synuclein in ...... es kallikrein-6 and calpain-1.
@ast
Accumulation of α-synuclein in ...... es kallikrein-6 and calpain-1.
@en
Accumulation of α-synuclein in ...... es kallikrein-6 and calpain-1.
@nl
prefLabel
Accumulation of α-synuclein in ...... es kallikrein-6 and calpain-1.
@ast
Accumulation of α-synuclein in ...... es kallikrein-6 and calpain-1.
@en
Accumulation of α-synuclein in ...... es kallikrein-6 and calpain-1.
@nl
P2093
P2860
P1476
Accumulation of α-synuclein in ...... es kallikrein-6 and calpain-1.
@en
P2093
J Scott Miners
Marta Swirski
Ruth Renfrew
P2860
P2888
P356
10.1186/S40478-014-0164-0
P577
2014-12-05T00:00:00Z
P5875
P6179
1047638023