The Talpid3 gene (KIAA0586) encodes a centrosomal protein that is essential for primary cilia formation
about
The CP110-interacting proteins Talpid3 and Cep290 play overlapping and distinct roles in cilia assemblyPhysiology and pathophysiology of respiratory mucosa of the nose and the paranasal sinuses.A primer on the mouse basal bodyCellular Mechanisms of Ciliary Length ControlA unified model for left-right asymmetry? Comparison and synthesis of molecular models of embryonic lateralitySalient features of the ciliated organ of asymmetryConserved roles for cytoskeletal components in determining laterality.The ciliary membrane.MKS and NPHP modules cooperate to establish basal body/transition zone membrane associations and ciliary gate function during ciliogenesisTalpid3-binding centrosomal protein Cep120 is required for centriole duplication and proliferation of cerebellar granule neuron progenitorsGeneration of mice with functional inactivation of talpid3, a gene first identified in chickenMutations in human homologue of chicken talpid3 gene (KIAA0586) cause a hybrid ciliopathy with overlapping features of Jeune and Joubert syndromesThe primary cilium: a signalling centre during vertebrate developmentFoxj1 regulates floor plate cilia architecture and modifies the response of cells to sonic hedgehog signallingCell movements at Hensen's node establish left/right asymmetric gene expression in the chick.Gli2a protein localization reveals a role for Iguana/DZIP1 in primary ciliogenesis and a dependence of Hedgehog signal transduction on primary cilia in the zebrafish.A primary cilia-dependent etiology for midline facial disorders.Mechanism and evolution of cytosolic Hedgehog signal transductionLimbs made to measure.The cellular and molecular etiology of the craniofacial defects in the avian ciliopathic mutant talpid2.The chicken left right organizer has nonmotile cilia which are lost in a stage-dependent manner in the talpid(3) ciliopathy.A role for smoothened during murine lens and cornea development.Targeted mutation of the talpid3 gene in zebrafish reveals its conserved requirement for ciliogenesis and Hedgehog signalling across the vertebrates.Functional analysis of the microtubule-interacting transcriptome.Stages of ciliogenesis and regulation of ciliary lengthFunctional genome-wide siRNA screen identifies KIAA0586 as mutated in Joubert syndrome.KIAA0586 is Mutated in Joubert SyndromeUtilizing the chicken as an animal model for human craniofacial ciliopathies.Dampened Hedgehog signaling but normal Wnt signaling in zebrafish without cilia.The primary cilium as a Hedgehog signal transduction machine.Regulating the transition from centriole to basal bodyPrimary cilia and organogenesis: is Hedgehog the only sculptor?The ciliary cytoskeleton.Primary cilia and graded Sonic Hedgehog signaling.Centrosome positioning in non-dividing cells.Mutations in ARMC9, which Encodes a Basal Body Protein, Cause Joubert Syndrome in Humans and Ciliopathy Phenotypes in Zebrafish.Cilia in vertebrate left-right patterning.Primary Cilia and Mammalian Hedgehog Signaling.Evolution of antero-posterior patterning of the limb: insights from the chick.Inactivation of Sonic Hedgehog Signaling and Polydactyly in Limbs of Hereditary Multiple Malformation, a Novel Type of Talpid Mutant.
P2860
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P2860
The Talpid3 gene (KIAA0586) encodes a centrosomal protein that is essential for primary cilia formation
description
2009 nî lūn-bûn
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2009 թուականի Փետրուարին հրատարակուած գիտական յօդուած
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2009 թվականի փետրվարին հրատարակված գիտական հոդված
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2009年の論文
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2009年学术文章
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2009年学术文章
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2009年学术文章
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2009年学术文章
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2009年学术文章
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2009年學術文章
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name
The Talpid3 gene (KIAA0586) en ...... al for primary cilia formation
@ast
The Talpid3 gene (KIAA0586) en ...... al for primary cilia formation
@en
The Talpid3 gene (KIAA0586) en ...... al for primary cilia formation
@en-gb
The Talpid3 gene (KIAA0586) en ...... al for primary cilia formation
@nl
type
label
The Talpid3 gene (KIAA0586) en ...... al for primary cilia formation
@ast
The Talpid3 gene (KIAA0586) en ...... al for primary cilia formation
@en
The Talpid3 gene (KIAA0586) en ...... al for primary cilia formation
@en-gb
The Talpid3 gene (KIAA0586) en ...... al for primary cilia formation
@nl
prefLabel
The Talpid3 gene (KIAA0586) en ...... al for primary cilia formation
@ast
The Talpid3 gene (KIAA0586) en ...... al for primary cilia formation
@en
The Talpid3 gene (KIAA0586) en ...... al for primary cilia formation
@en-gb
The Talpid3 gene (KIAA0586) en ...... al for primary cilia formation
@nl
P2093
P2860
P50
P3181
P356
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The Talpid3 gene (KIAA0586) en ...... al for primary cilia formation
@en
P2093
Fiona Bangs
I Robert Paton
John James
Paul Whitley
P2860
P304
P3181
P356
10.1242/DEV.028464
P407
P577
2009-02-01T00:00:00Z