Human mitochondrial ClpP is a stable heptamer that assembles into a tetradecamer in the presence of ClpX
about
Multitasking in the mitochondrion by the ATP-dependent Lon proteaseInsights into Structural Network Responsible for Oligomerization and Activity of Bacterial Virulence Regulator Caseinolytic Protease P (ClpP) ProteinMitochondrial protein quality control: the mechanisms guarding mitochondrial healthMitochondrial quality control in the myocardium: cooperation between protein degradation and mitophagyAdaptor protein controlled oligomerization activates the AAA+ protein ClpCAssembly and proteolytic processing of mycobacterial ClpP1 and ClpP2.ClpXP, an ATP-powered unfolding and protein-degradation machineAAA+ chaperones and acyldepsipeptides activate the ClpP protease via conformational control.Impact of the N-terminal amino acid on targeted protein degradation.Protein degradation within mitochondria: versatile activities of AAA proteases and other peptidases.Cleavage Specificity of Mycobacterium tuberculosis ClpP1P2 Protease and Identification of Novel Peptide Substrates and Boronate Inhibitors with Anti-bacterial Activity.Inhibition of the Mitochondrial Protease ClpP as a Therapeutic Strategy for Human Acute Myeloid Leukemia.Turned on for degradation: ATPase-independent degradation by ClpP.Mitochondrial ClpP activity is required for cisplatin resistance in human cells.ClpP: a distinctive family of cylindrical energy-dependent serine proteases.Protein quality control in mitochondria.Diverse functions of mitochondrial AAA+ proteins: protein activation, disaggregation, and degradation.Mitochondrial stress: a bridge between mitochondrial dysfunction and metabolic diseases?Quality control of mitochondrial proteostasis.Mechanistic insights into bacterial AAA+ proteases and protein-remodelling machines.Two isoforms of Clp peptidase in Pseudomonas aeruginosa control distinct aspects of cellular physiology.Genetics of mitochondrial dysfunction and infertility.Diphenylarsinic acid promotes degradation of glutaminase C by mitochondrial Lon protease.LON is the master protease that protects against protein aggregation in human mitochondria through direct degradation of misfolded proteins.The active ClpP protease from M. tuberculosis is a complex composed of a heptameric ClpP1 and a ClpP2 ring.Substrate delivery by the AAA+ ClpX and ClpC1 unfoldases activates the mycobacterial ClpP1P2 peptidaseThe mechanism of caseinolytic protease (ClpP) inhibition.Proteases and protease inhibitors in infectious diseases.Expanding the genotypic spectrum of Perrault syndrome.Downregulation of ClpR2 leads to reduced accumulation of the ClpPRS protease complex and defects in chloroplast biogenesis in Arabidopsis.Perrault syndrome type 3 caused by diverse molecular defects in CLPP
P2860
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P2860
Human mitochondrial ClpP is a stable heptamer that assembles into a tetradecamer in the presence of ClpX
description
2005 nî lūn-bûn
@nan
2005 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Human mitochondrial ClpP is a ...... ecamer in the presence of ClpX
@ast
Human mitochondrial ClpP is a ...... ecamer in the presence of ClpX
@en
Human mitochondrial ClpP is a ...... ecamer in the presence of ClpX
@en-gb
Human mitochondrial ClpP is a ...... ecamer in the presence of ClpX
@nl
type
label
Human mitochondrial ClpP is a ...... ecamer in the presence of ClpX
@ast
Human mitochondrial ClpP is a ...... ecamer in the presence of ClpX
@en
Human mitochondrial ClpP is a ...... ecamer in the presence of ClpX
@en-gb
Human mitochondrial ClpP is a ...... ecamer in the presence of ClpX
@nl
prefLabel
Human mitochondrial ClpP is a ...... ecamer in the presence of ClpX
@ast
Human mitochondrial ClpP is a ...... ecamer in the presence of ClpX
@en
Human mitochondrial ClpP is a ...... ecamer in the presence of ClpX
@en-gb
Human mitochondrial ClpP is a ...... ecamer in the presence of ClpX
@nl
P2093
P2860
P921
P356
P1476
Human mitochondrial ClpP is a ...... ecamer in the presence of ClpX
@en
P2093
Ann Ginsburg
Joaquin Ortega
Mariana N Dimitrova
Michael R Maurizi
Sung Gyun Kang
P2860
P304
P356
10.1074/JBC.M507240200
P407
P577
2005-10-21T00:00:00Z