Structural basis for the activation of 20S proteasomes by 11S regulators
about
The alpha4 and alpha7 subunits and assembly of the 20S proteasomeVariably modulated gating of the 26S proteasome by ATP and polyubiquitinHuman mitochondrial ClpP is a stable heptamer that assembles into a tetradecamer in the presence of ClpXProteasomal ATPase-associated factor 1 negatively regulates proteasome activity by interacting with proteasomal ATPasesPA200, a nuclear proteasome activator involved in DNA repair.Mechanism of gate opening in the 20S proteasome by the proteasomal ATPasesDocking of the proteasomal ATPases' carboxyl termini in the 20S proteasome's alpha ring opens the gate for substrate entryBacterial ProteasomesMHC class I antigen processing and presenting machinery: organization, function, and defects in tumor cellsFunctions of the 19S complex in proteasomal degradationInteractions of PAN's C-termini with archaeal 20S proteasome and implications for the eukaryotic proteasomeāATPase interactionsStructural Models for Interactions between the 20S Proteasome and Its PAN/19S ActivatorsStructure of a Blm10 Complex Reveals Common Mechanisms for Proteasome Binding and Gate OpeningDynamic regulation of archaeal proteasome gate opening as studied by TROSY NMRCryo-electron microscopy structure of the 30S subunit in complex with the YjeQ biogenesis factorStructural insights into the conformational diversity of ClpP from Bacillus subtilisDifferential global structural changes in the core particle of yeast and mouse proteasome induced by ligand bindingStructure characterization of the 26S proteasome.Molecular architecture and assembly of the eukaryotic proteasomeThe immunoproteasome and viral infection: a complex regulator of inflammationThe C-terminal extension of the beta7 subunit and activator complexes stabilize nascent 20 S proteasomes and promote their maturation.Hexameric assembly of the proteasomal ATPases is templated through their C terminiBlm10 protein promotes proteasomal substrate turnover by an active gating mechanismRPN4 is a ligand, substrate, and transcriptional regulator of the 26S proteasome: a negative feedback circuit.The Cdc48-Vms1 complex maintains 26S proteasome architecture.The HEAT repeat protein Blm10 regulates the yeast proteasome by capping the core particle.Structural defects in the regulatory particle-core particle interface of the proteasome induce a novel proteasome stress responseOverexpression of PLK3 Mediates the Degradation of Abnormal Prion Proteins Dependent on Chaperone-Mediated AutophagyThe ER aminopeptidase ERAP1 enhances or limits antigen presentation by trimming epitopes to 8-9 residuesAn asymmetric interface between the regulatory and core particles of the proteasomeThe ubiquitin proteasome system and myocardial ischemiaDifferential roles of the COOH termini of AAA subunits of PA700 (19 S regulator) in asymmetric assembly and activation of the 26 S proteasomeLysine 188 substitutions convert the pattern of proteasome activation by REGgamma to that of REGs alpha and beta.The ubiquitin-proteasome pathway and proteasome inhibitorsRegulation of proteasome activity in health and diseaseMycobacterium tuberculosis prcBA genes encode a gated proteasome with broad oligopeptide specificityDifferential expression of tapasin and immunoproteasome subunits in adenovirus type 5- versus type 12-transformed cellsRecognition and processing of ubiquitin-protein conjugates by the proteasomeOverview of protein structural and functional folds.Changes in proteasome structure and function caused by HAMLET in tumor cells.
P2860
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P2860
Structural basis for the activation of 20S proteasomes by 11S regulators
description
2000 nĆ® lÅ«n-bĆ»n
@nan
2000 Õ©ÕøÖÕ”ÕÆÕ”Õ¶Õ« ÕÕøÕµÕ„Õ“Õ¢Õ„ÖÕ«Õ¶ Õ°ÖÕ”ÕæÕ”ÖÕ”ÕÆÕøÖÕ”Õ® Õ£Õ«ÕæÕ”ÕÆÕ”Õ¶ ÕµÖ
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@hyw
2000 Õ©Õ¾Õ”ÕÆÕ”Õ¶Õ« Õ¶ÕøÕµÕ„Õ“Õ¢Õ„ÖÕ«Õ¶ Õ°ÖÕ”ÕæÕ”ÖÕ”ÕÆÕ¾Õ”Õ® Õ£Õ«ÕæÕ”ÕÆÕ”Õ¶ Õ°ÕøÕ¤Õ¾Õ”Õ®
@hy
2000幓ć®č«ę
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2000幓č«ę
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2000幓č«ę
@zh-hant
2000幓č«ę
@zh-hk
2000幓č«ę
@zh-mo
2000幓č«ę
@zh-tw
2000幓č®ŗę
@wuu
name
Structural basis for the activation of 20S proteasomes by 11S regulators
@ast
Structural basis for the activation of 20S proteasomes by 11S regulators
@en
Structural basis for the activation of 20S proteasomes by 11S regulators
@nl
type
label
Structural basis for the activation of 20S proteasomes by 11S regulators
@ast
Structural basis for the activation of 20S proteasomes by 11S regulators
@en
Structural basis for the activation of 20S proteasomes by 11S regulators
@nl
prefLabel
Structural basis for the activation of 20S proteasomes by 11S regulators
@ast
Structural basis for the activation of 20S proteasomes by 11S regulators
@en
Structural basis for the activation of 20S proteasomes by 11S regulators
@nl
P2093
P356
P1433
P1476
Structural basis for the activation of 20S proteasomes by 11S regulators
@en
P2093
E I Masters
F G Whitby
J R Knowlton
P2888
P304
P356
10.1038/35040607
P407
P577
2000-11-02T00:00:00Z
P6179
1028028298