Cloning and characterization of hOGG1, a human homolog of the OGG1 gene of Saccharomyces cerevisiae
about
8-Oxoguanine DNA glycosylase (OGG1) deficiency increases susceptibility to obesity and metabolic dysfunctionActivation of apurinic/apyrimidinic endonuclease in human cells by reactive oxygen species and its correlation with their adaptive response to genotoxicity of free radicalsIdentification and characterization of a human DNA glycosylase for repair of modified bases in oxidatively damaged DNALocalization of the Fanconi anemia complementation group D gene to a 200-kb region on chromosome 3p25.3.Early steps in the DNA base excision/single-strand interruption repair pathway in mammalian cellsAccumulation of premutagenic DNA lesions in mice defective in removal of oxidative base damageAPE1-dependent repair of DNA single-strand breaks containing 3'-end 8-oxoguanineFunctional characterization of two human MutY homolog (hMYH) missense mutations (R227W and V232F) that lie within the putative hMSH6 binding domain and are associated with hMYH polyposisDynamic relocalization of hOGG1 during the cell cycle is disrupted in cells harbouring the hOGG1-Cys326 polymorphic variantNEIL1 excises 3' end proximal oxidative DNA lesions resistant to cleavage by NTH1 and OGG1.Dimerization and opposite base-dependent catalytic impairment of polymorphic S326C OGG1 glycosylaseGut Microbiota Imbalance and Base Excision Repair Dynamics in Colon CancerThe current state of eukaryotic DNA base damage and repairCellular levels of 8-oxoguanine in either DNA or the nucleotide pool play pivotal roles in carcinogenesis and survival of cancer cellsDNA glycosylases: in DNA repair and beyondBase excision repair and cancerStructural Characterization of Clostridium acetobutylicum 8-Oxoguanine DNA Glycosylase in Its Apo Form and in Complex with 8-OxodeoxyguanosineCrystal Structures of Two Archaeal 8-Oxoguanine DNA Glycosylases Provide Structural Insight into Guanine/8-Oxoguanine DistinctionStructural basis for the lack of opposite base specificity of Clostridium acetobutylicum 8-oxoguanine DNA glycosylaseThe C-terminal Lysine of Ogg2 DNA Glycosylases is a Major Molecular Determinant for Guanine/8-Oxoguanine DistinctionMechanisms of hemorrhagic cystitis.Inactivation of Saccharomyces cerevisiae OGG1 DNA repair gene leads to an increased frequency of mitochondrial mutants.Expression and differential intracellular localization of two major forms of human 8-oxoguanine DNA glycosylase encoded by alternatively spliced OGG1 mRNAsRepair of oxidized bases in DNA bubble structures by human DNA glycosylases NEIL1 and NEIL2PARP-1 expression is increased in colon adenoma and carcinoma and correlates with OGG1Base excision repairDNA polymerase beta is the major dRP lyase involved in repair of oxidative base lesions in DNA by mammalian cell extractsTranscriptional mutagenesis induced by 8-oxoguanine in mammalian cellsTargeted deletion of alkylpurine-DNA-N-glycosylase in mice eliminates repair of 1,N6-ethenoadenine and hypoxanthine but not of 3,N4-ethenocytosine or 8-oxoguanineIdentification of human MutY homolog (hMYH) as a repair enzyme for 2-hydroxyadenine in DNA and detection of multiple forms of hMYH located in nuclei and mitochondriaStimulation of human 8-oxoguanine-DNA glycosylase by AP-endonuclease: potential coordination of the initial steps in base excision repairReactive oxygen species-induced molecular damage and its application in pathology.Characterization of the recombinant MutY homolog, an adenine DNA glycosylase, from yeast Schizosaccharomyces pombe.Pa-AGOG, the founding member of a new family of archaeal 8-oxoguanine DNA-glycosylases.Increased mRNA expression levels of ERCC1, OGG1 and RAI in colorectal adenomas and carcinomas.Targeting of mutant hogg1 in mammalian mitochondria and nucleus: effect on cellular survival upon oxidative stress.Reduced repair of 8-hydroxyguanine in the human breast cancer cell line, HCC1937Human DNA repair systems: an overview.RPA physically interacts with the human DNA glycosylase NEIL1 to regulate excision of oxidative DNA base damage in primer-template structures.Experimental study of oxidative DNA damage.
P2860
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P2860
Cloning and characterization of hOGG1, a human homolog of the OGG1 gene of Saccharomyces cerevisiae
description
1997 nî lūn-bûn
@nan
1997 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Cloning and characterization o ...... ne of Saccharomyces cerevisiae
@ast
Cloning and characterization o ...... ne of Saccharomyces cerevisiae
@en
Cloning and characterization o ...... ne of Saccharomyces cerevisiae
@en-gb
Cloning and characterization o ...... ne of Saccharomyces cerevisiae
@nl
type
label
Cloning and characterization o ...... ne of Saccharomyces cerevisiae
@ast
Cloning and characterization o ...... ne of Saccharomyces cerevisiae
@en
Cloning and characterization o ...... ne of Saccharomyces cerevisiae
@en-gb
Cloning and characterization o ...... ne of Saccharomyces cerevisiae
@nl
prefLabel
Cloning and characterization o ...... ne of Saccharomyces cerevisiae
@ast
Cloning and characterization o ...... ne of Saccharomyces cerevisiae
@en
Cloning and characterization o ...... ne of Saccharomyces cerevisiae
@en-gb
Cloning and characterization o ...... ne of Saccharomyces cerevisiae
@nl
P2093
P2860
P921
P3181
P356
P1476
Cloning and characterization o ...... ne of Saccharomyces cerevisiae
@en
P2093
P2860
P304
P3181
P356
10.1073/PNAS.94.15.8010
P407
P577
1997-07-01T00:00:00Z