DNA polymerase beta is the major dRP lyase involved in repair of oxidative base lesions in DNA by mammalian cell extracts - Test2 - elhamkhani - TriplyDB

DNA polymerase beta is the major dRP lyase involved in repair of oxidative base lesions in DNA by mammalian cell extracts

DNA polymerase beta is the major dRP lyase involved in repair of oxidative base lesions in DNA by mammalian cell extracts

http://www.wikidata.org/entity/Q28365541

about

Ku is a 5'-dRP/AP lyase that excises nucleotide damage near broken ends Ubiquitin ligase ARF-BP1/Mule modulates base excision repair Role of XRCC1 in the coordination and stimulation of oxidative DNA damage repair initiated by the DNA glycosylase hOGG1 In situ analysis of repair processes for oxidative DNA damage in mammalian cells.Reconstitution of the base excision repair pathway for 7,8-dihydro-8-oxoguanine with purified human proteins Inhibition of human DNA polymerase beta activity by the anticancer prodrug Cloretazine.Repair of single-strand DNA interruptions by redundant pathways and its implication in cellular sensitivity to DNA-damaging agents Micromolar concentrations of hydrogen peroxide induce oxidative DNA lesions more efficiently than millimolar concentrations in mammalian cells.Specificity of the dRP/AP lyase of Ku promotes nonhomologous end joining (NHEJ) fidelity at damaged ends.Impact of reduced levels of APE1 transcripts on the survival of patients with urothelial carcinoma of the bladder.8-oxoguanine DNA glycosylases: one lesion, three subfamilies Special AT-rich Sequence-binding Protein 1 (SATB1) Functions as an Accessory Factor in Base Excision Repair.8-Oxoguanine Affects DNA Backbone Conformation in the EcoRI Recognition Site and Inhibits Its Cleavage by the Enzyme The K167I variant of DNA polymerase β that is found in Esophageal Carcinoma patients impairs polymerase activity and BER.Evidence for base excision repair processing of DNA interstrand crosslinks.R152C DNA Pol β mutation impairs base excision repair and induces cellular transformation Mutation of DNA Polymerase β R137Q Results in Retarded Embryo Development Due to Impaired DNA Base Excision Repair in Mice Human DNA polymerase beta polymorphism, Arg137Gln, impairs its polymerase activity and interaction with PCNA and the cellular base excision repair capacity.Widespread transcriptional gene inactivation initiated by a repair intermediate of 8-oxoguanine.An 8-oxo-guanine repair pathway coordinated by MUTYH glycosylase and DNA polymerase lambda.Targeting DNA polymerase ß for therapeutic intervention.DNA base repair--recognition and initiation of catalysis.Biological and therapeutic relevance of nonreplicative DNA polymerases to cancer.A CRISPR/Cas9 approach reveals that the polymerase activity of DNA polymerase β is dispensable for HIV-1 infection in dividing and nondividing cells DNA end-processing enzyme polynucleotide kinase as a potential target in the treatment of cancer.Mammalian 8-oxoguanine DNA glycosylase 1 incises 8-oxoadenine opposite cytosine in nuclei and mitochondria, while a different glycosylase incises 8-oxoadenine opposite guanine in nuclei.Poly(ADP-ribose) polymerase-1 (PARP-1) is required in murine cell lines for base excision repair of oxidative DNA damage in the absence of DNA polymerase beta.Catalytic mechanism of Escherichia coli endonuclease VIII: roles of the intercalation loop and the zinc finger The DNA repair function of CUX1 contributes to radioresistance.Repair of dihydrouracil supported by base excision repair in mNTH1 knock-out cell extracts.Uniform Free-Energy Profiles of the P-O Bond Formation and Cleavage Reactions Catalyzed by DNA Polymerases β and λ.Apurinic/apyrimidinic endonuclease (APE/REF-1) haploinsufficient mice display tissue-specific differences in DNA polymerase beta-dependent base excision repair.Role of the oxidative DNA damage repair gene OGG1 in colorectal tumorigenesis.Deoxyribophosphate lyase activity of mammalian endonuclease VIII-like proteins.Oxidative damage to epigenetically methylated sites affects DNA stability, dynamics and enzymatic demethylation

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P2860

DNA polymerase beta is the major dRP lyase involved in repair of oxidative base lesions in DNA by mammalian cell extracts

http://www.wikidata.org/entity/Q28365541

description

2001 nî lūn-bûn

@nan

2001 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2001 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

2001年の論文

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2001年論文

@yue

2001年論文

@zh-hant

2001年論文

@zh-hk

2001年論文

@zh-mo

2001年論文

@zh-tw

2001年论文

@wuu

name

DNA polymerase beta is the maj ...... DNA by mammalian cell extracts

@ast

DNA polymerase beta is the maj ...... DNA by mammalian cell extracts

@en

DNA polymerase beta is the maj ...... DNA by mammalian cell extracts

@nl

type

label

DNA polymerase beta is the maj ...... DNA by mammalian cell extracts

@ast

DNA polymerase beta is the maj ...... DNA by mammalian cell extracts

@en

DNA polymerase beta is the maj ...... DNA by mammalian cell extracts

@nl

prefLabel

DNA polymerase beta is the maj ...... DNA by mammalian cell extracts

@ast

DNA polymerase beta is the maj ...... DNA by mammalian cell extracts

@en

DNA polymerase beta is the maj ...... DNA by mammalian cell extracts

@nl

P1433

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P1433

The EMBO Journal

P1476

DNA polymerase beta is the maj ...... DNA by mammalian cell extracts

@en

P2093

Allinson SL

http://www.w3.org/2001/XMLSchema#string

Dianov GL

http://www.w3.org/2001/XMLSchema#string

Dianova II

http://www.w3.org/2001/XMLSchema#string

P2860

Instability and decay of the primary structure of DNA

Cloning and expression of APE, the cDNA encoding the major human apurinic endonuclease: definition of a family of DNA repair enzymes

Cloning of a human homolog of the yeast OGG1 gene that is involved in the repair of oxidative DNA damage

Cloning and characterization of a functional human homolog of Escherichia coli endonuclease III

Cloning and characterization of hOGG1, a human homolog of the OGG1 gene of Saccharomyces cerevisiae

Isolation of cDNA clones encoding a human apurinic/apyrimidinic endonuclease that corrects DNA repair and mutagenesis defects in E. coli xth (exonuclease III) mutants

DNA-bound structures and mutants reveal abasic DNA binding by APE1 and DNA repair coordination [corrected]

The human OGG1 gene: structure, functions, and its implication in the process of carcinogenesis

XRCC1 stimulates human polynucleotide kinase activity at damaged DNA termini and accelerates DNA single-strand break repair

Oxidative damage to DNA in mammalian chromatin

P304

6919-6926

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scholarly article

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336135

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10.1093/EMBOJ/20.23.6919

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P433

23

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P478

20

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2001-12-01T00:00:00Z

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11628407

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P698

11726527

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125762

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