Huntingtin is a cytoplasmic protein associated with vesicles in human and rat brain neurons
about
Mutation in archain 1, a subunit of COPI coatomer complex, causes diluted coat color and Purkinje cell degenerationHuntingtin is critical both pre- and postsynaptically for long-term learning-related synaptic plasticity in AplysiaHuntingtin interacting proteins are genetic modifiers of neurodegenerationThe Huntington's disease protein interacts with p53 and CREB-binding protein and represses transcriptionOligonucleotide therapeutic approaches for Huntington diseaseHIP1 and HIP12 display differential binding to F-actin, AP2, and clathrin. Identification of a novel interaction with clathrin light chainOptineurin links myosin VI to the Golgi complex and is involved in Golgi organization and exocytosisHuntingtin-interacting protein 1-mediated neuronal cell death occurs through intrinsic apoptotic pathways and mitochondrial alterationsHuntingtin is ubiquitinated and interacts with a specific ubiquitin-conjugating enzymeHuntingtin-interacting proteins, HIP14 and HIP14L, mediate dual functions, palmitoyl acyltransferase and Mg2+ transportHuntingtin has a membrane association signal that can modulate huntingtin aggregation, nuclear entry and toxicityPolyglutamine expansion of huntingtin impairs its nuclear exportCdc42-interacting protein 4 binds to huntingtin: neuropathologic and biological evidence for a role in Huntington's diseaseHuntingtin in health and diseaseMetabolic dysfunction in Alzheimer's disease and related neurodegenerative disordersHuntingtin-associated protein (HAP1): discrete neuronal localizations in the brain resemble those of neuronal nitric oxide synthaseThe Gln-Ala repeat transcriptional activator CA150 interacts with huntingtin: neuropathologic and genetic evidence for a role in Huntington's disease pathogenesisTissue transglutaminase overexpression does not modify the disease phenotype of the R6/2 mouse model of Huntington's diseasePalmitoylation of huntingtin by HIP14 is essential for its trafficking and functionThe localization and interactions of huntingtinTransgenic models of Huntington's diseaseAge at onset of Huntington disease is not modulated by the R72P variation in TP53 and the R196K variation in the gene coding for the human caspase activated DNase (hCAD)The Influence of Na(+), K(+)-ATPase on Glutamate Signaling in Neurodegenerative Diseases and SenescenceSumoylation in Synaptic Function and DysfunctionCharcot-Marie-Tooth disease and intracellular trafficIron dysregulation in Huntington's diseaseSystems-Level G Protein-Coupled Receptor Therapy Across a Neurodegenerative Continuum by the GLP-1 Receptor SystemPGC-1α, mitochondrial dysfunction, and Huntington's diseaseModeling Huntington's disease with induced pluripotent stem cellsGenetics and neuropathology of Huntington's diseaseHydrophobically Modified siRNAs Silence Huntingtin mRNA in Primary Neurons and Mouse BrainStructure and Topology of the Huntingtin 1–17 Membrane Anchor by a Combined Solution and Solid-State NMR ApproachMixed lineage kinase 2 interacts with clathrin and influences clathrin-coated vesicle traffickingCharacterization of Endophilin B1b, a brain-specific membrane-associated lysophosphatidic acid acyl transferase with properties distinct from endophilin A1Normal huntingtin function: an alternative approach to Huntington's diseaseA threonine to isoleucine missense mutation in the pericentriolar material 1 gene is strongly associated with schizophreniaHuntington's diseaseAutophagy Activation by Transcription Factor EB (TFEB) in Striatum of HDQ175/Q7 Mice.Inhibition of calpain cleavage of huntingtin reduces toxicity: accumulation of calpain/caspase fragments in the nucleusCellular localization and development of neuronal intranuclear inclusions in striatal and cortical neurons in R6/2 transgenic mice
P2860
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P2860
Huntingtin is a cytoplasmic protein associated with vesicles in human and rat brain neurons
description
1995 nî lūn-bûn
@nan
1995 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
Huntingtin is a cytoplasmic pr ...... in human and rat brain neurons
@ast
Huntingtin is a cytoplasmic pr ...... in human and rat brain neurons
@en
Huntingtin is a cytoplasmic pr ...... in human and rat brain neurons
@en-gb
Huntingtin is a cytoplasmic pr ...... in human and rat brain neurons
@nl
type
label
Huntingtin is a cytoplasmic pr ...... in human and rat brain neurons
@ast
Huntingtin is a cytoplasmic pr ...... in human and rat brain neurons
@en
Huntingtin is a cytoplasmic pr ...... in human and rat brain neurons
@en-gb
Huntingtin is a cytoplasmic pr ...... in human and rat brain neurons
@nl
prefLabel
Huntingtin is a cytoplasmic pr ...... in human and rat brain neurons
@ast
Huntingtin is a cytoplasmic pr ...... in human and rat brain neurons
@en
Huntingtin is a cytoplasmic pr ...... in human and rat brain neurons
@en-gb
Huntingtin is a cytoplasmic pr ...... in human and rat brain neurons
@nl
P2093
P3181
P1433
P1476
Huntingtin is a cytoplasmic pr ...... in human and rat brain neurons
@en
P2093
J P Vonsattel
M DiFiglia
R Carraway
S A Reeves
P304
P3181
P356
10.1016/0896-6273(95)90346-1
P407
P577
1995-05-01T00:00:00Z