Upregulation of calcium/calmodulin-dependent protein kinase IV improves memory formation and rescues memory loss with aging
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Genes and signaling pathways involved in memory enhancement in mutant miceAge-related changes in behavior in C57BL/6J mice from young adulthood to middle ageDeceivingly dynamic: Learning-dependent changes in stathmin and microtubulesComprehensive behavioral analysis of calcium/calmodulin-dependent protein kinase IV knockout mice.Transgenic up-regulation of alpha-CaMKII in forebrain leads to increased anxiety-like behaviors and aggression.Dysfunction of the RAR/RXR signaling pathway in the forebrain impairs hippocampal memory and synaptic plasticity.Constitutive activation of CREB in mice enhances temporal association learning and increases hippocampal CA1 neuronal spine density and complexity.Suppression of InsP3 receptor-mediated Ca2+ signaling alleviates mutant presenilin-linked familial Alzheimer's disease pathogenesis.DREAM (downstream regulatory element antagonist modulator) contributes to synaptic depression and contextual fear memory.Enhancement of fear memory by retrieval through reconsolidationCalcium/calmodulin-dependent kinase IV contributes to translation-dependent early synaptic potentiation in the anterior cingulate cortex of adult mice.Reduced neuronal signaling in the ageing apolipoprotein-E4 targeted replacement female mice.The PDE4 inhibitor HT-0712 improves hippocampus-dependent memory in aged mice.Properties of contextual memory formed in the absence of αCaMKII autophosphorylationThe molecular and cellular biology of enhanced cognition.Calcium/calmodulin-dependent protein kinase IV mediates distinct features of basal and activity-dependent dendrite complexityTORC2: a novel target for treating age-associated memory impairmentHippocampal Wnt3a is Necessary and Sufficient for Contextual Fear Memory Acquisition and Consolidation.Characterizing cognitive aging of spatial and contextual memory in animal modelsEpigenetic modification of PKMζ rescues aging-related cognitive impairment.Memory deficits are associated with impaired ability to modulate neuronal excitability in middle-aged miceCa2+/calmodulin-dependent protein kinase IV links group I metabotropic glutamate receptors to fragile X mental retardation protein in cingulate cortex.Calcium signaling in cognition and aging-dependent cognitive decline.Circadian rhythms and sleep--the metabolic connection.Role of wnt signaling in the control of adult hippocampal functioning in health and disease: therapeutic implications.Targeting the NMDA receptor subunit NR2B for treating or preventing age-related memory decline.Design, synthesis, and biological evaluation of pyrimidine derivatives as potential inhibitors of human calcium/calmodulin-dependent protein kinase IV.Systems Vaccinology: Applications, Trends, and Perspectives.Calcium/calmodulin-dependent protein kinase kinase β is neuroprotective in stroke in aged mice.Calcium/calmodulin-dependent protein kinase type IV is a target gene of the Wnt/beta-catenin signaling pathway.Vitamin B1-deficient mice show impairment of hippocampus-dependent memory formation and loss of hippocampal neurons and dendritic spines: potential microendophenotypes of Wernicke-Korsakoff syndrome.Hippocampal neurogenesis enhancers promote forgetting of remote fear memory after hippocampal reactivation by retrieval.CaMKIV over-expression boosts cortical 4-7 Hz oscillations during learning and 1-4 Hz delta oscillations during sleep.Function of Ca2+ -/calmodulin-dependent protein kinase IV in Ca2+ -stimulated neuronal signaling and behavior.Induction and requirement of gene expression in the anterior cingulate cortex and medial prefrontal cortex for the consolidation of inhibitory avoidance memory.PI3K regulates BMAL1/CLOCK-mediated circadian transcription from the Dbp promoter.PARP-1 activity is required for the reconsolidation and extinction of contextual fear memory.Genistein protects hippocampal neurons against injury by regulating calcium/calmodulin dependent protein kinase IV protein levels in Alzheimer's disease model rats.Selective inhibition of miR-92 in hippocampal neurons alters contextual fear memory.Evidence of vanillin binding to CAMKIV explains the anti-cancer mechanism in human hepatic carcinoma and neuroblastoma cells.
P2860
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P2860
Upregulation of calcium/calmodulin-dependent protein kinase IV improves memory formation and rescues memory loss with aging
description
2008 nî lūn-bûn
@nan
2008 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Upregulation of calcium/calmod ...... rescues memory loss with aging
@ast
Upregulation of calcium/calmod ...... rescues memory loss with aging
@en
Upregulation of calcium/calmod ...... rescues memory loss with aging
@en-gb
Upregulation of calcium/calmod ...... rescues memory loss with aging
@nl
type
label
Upregulation of calcium/calmod ...... rescues memory loss with aging
@ast
Upregulation of calcium/calmod ...... rescues memory loss with aging
@en
Upregulation of calcium/calmod ...... rescues memory loss with aging
@en-gb
Upregulation of calcium/calmod ...... rescues memory loss with aging
@nl
prefLabel
Upregulation of calcium/calmod ...... rescues memory loss with aging
@ast
Upregulation of calcium/calmod ...... rescues memory loss with aging
@en
Upregulation of calcium/calmod ...... rescues memory loss with aging
@en-gb
Upregulation of calcium/calmod ...... rescues memory loss with aging
@nl
P2093
P3181
P1476
Upregulation of calcium/calmod ...... rescues memory loss with aging
@en
P2093
Akinobu Suzuki
Aya Kitamoto
Hiroki Toyoda
Hotaka Fukushima
Kenji Ueda
Masanori Nomoto
Ming-Gao Zhao
Nori Mamiya
P304
P3181
P356
10.1523/JNEUROSCI.2625-08.2008
P407
P50
P577
2008-10-01T00:00:00Z