Suppression of InsP3 receptor-mediated Ca2+ signaling alleviates mutant presenilin-linked familial Alzheimer's disease pathogenesis.
about
Calcium Dynamics Mediated by the Endoplasmic/Sarcoplasmic Reticulum and Related Diseases.Proteases Revisited: Roles and Therapeutic Implications in Fibrosis.Amyloid β production is regulated by β2-adrenergic signaling-mediated post-translational modifications of the ryanodine receptor.Aberrant calcium signaling by transglutaminase-mediated posttranslational modification of inositol 1,4,5-trisphosphate receptorsAnalyzing and Quantifying the Gain-of-Function Enhancement of IP3 Receptor Gating by Familial Alzheimer's Disease-Causing Mutants in Presenilins.Reduction of increased calcineurin activity rescues impaired homeostatic synaptic plasticity in presenilin 1 M146V mutant.Loss of presenilin function is associated with a selective gain of APP function.Impaired mitochondrial function due to familial Alzheimer's disease-causing presenilins mutants via Ca(2+) disruptions.A Bayesian Model for the Prediction and Early Diagnosis of Alzheimer's Disease.Endoplasmic reticulum calcium stores in dendritic spinesWhole exome sequence-based association analyses of plasma amyloid-β in African and European Americans; the Atherosclerosis Risk in Communities-Neurocognitive Study.Post-translational remodeling of ryanodine receptor induces calcium leak leading to Alzheimer's disease-like pathologies and cognitive deficits.Presenilin 1 Maintains Lysosomal Ca(2+) Homeostasis via TRPML1 by Regulating vATPase-Mediated Lysosome Acidification.Vitamin D, reactive oxygen species and calcium signalling in ageing and disease.Calcium's role as nuanced modulator of cellular physiology in the brain.Emerging pathways driving early synaptic pathology in Alzheimer's disease.Determining the Roles of Inositol Trisphosphate Receptors in Neurodegeneration: Interdisciplinary Perspectives on a Complex Topic.IP3 receptor mutations and brain diseases in human and rodents.Nitric oxide signaling is recruited as a compensatory mechanism for sustaining synaptic plasticity in Alzheimer's disease mice.Interactions of Mitochondria/Metabolism and Calcium Regulation in Alzheimer's Disease: A Calcinist Point of View.Inositol 1,4,5-trisphosphate receptors and neurodegenerative disorders.Autophagy and Alzheimer's Disease: From Molecular Mechanisms to Therapeutic Implications.Endoplasmic reticulum (ER) Ca2+-channel activity contributes to ER stress and cone death in cyclic nucleotide-gated channel deficiency.On the Role of Store-Operated Calcium Entry in Acute and Chronic Neurodegenerative Diseases.Roles of Gasotransmitters in Synaptic Plasticity and Neuropsychiatric Conditions.Dysregulation of Intracellular Calcium Signaling in Alzheimer's Disease
P2860
Q33755195-F3FBCF01-D55C-42D1-8BAA-D77C980384FFQ33795055-77789660-4D71-4CB3-98A8-9A08DE7892DCQ33806103-6C901E40-4BA0-4B91-AF94-C7D9BAD77E76Q34281322-581E84E5-8A19-4FF7-AD1F-F84CCFAE31C6Q35800316-C2EF0BEC-C253-4189-A06F-0C9D04D8F566Q36271540-308E47F2-1EE1-4BCC-A88E-FA8D83FB049BQ37026050-72082D84-1587-49C0-A9B8-071F28A085AFQ37383808-10CEFBE4-65DF-478A-BC6B-688874793691Q37731885-FEC15741-2498-4A31-A857-08758A6B6381Q38234887-2F87C697-0F94-4696-872D-A4B026228855Q38680904-66925BDB-94CC-497B-93FB-CE830509F694Q38718079-019F1B45-1111-468A-AD0A-BEE739C2507FQ38841488-FDA4A81B-346F-4084-878D-581881612087Q38885846-64FF1B78-861D-40E3-88CC-DF97C994CE45Q38935052-1D272F3C-42A0-4BDD-A632-EEC0215D5285Q38962140-7785C8AA-9D23-448B-944F-8C7248E7129BQ38988539-5D12D686-1CA3-4FE2-A1BE-EDCF17D79D22Q39140608-FEF00E77-FCF0-4AF8-B6E8-35E7878EE393Q40027781-41011356-66F6-4277-A2D9-493094CB2865Q48259154-A19E71AF-D37D-44A1-BA97-9CFAB7E44D29Q49666213-A4272893-3955-4CE5-AA55-E0B8907580A7Q50023771-56A39F0C-CF3A-477D-810B-D92533548608Q50438393-8D738C73-CEEC-4240-9A06-2B87C62AB625Q52721231-D9EF1EBE-6256-409D-96E1-C16A52ED1AD6Q55000550-ED7F56EA-4EA5-4EAD-83F5-F5E870B14A8BQ57131389-E633FB4A-2F57-4D69-B9E1-AFCC53621D66
P2860
Suppression of InsP3 receptor-mediated Ca2+ signaling alleviates mutant presenilin-linked familial Alzheimer's disease pathogenesis.
description
2014 nî lūn-bûn
@nan
2014 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Suppression of InsP3 receptor- ...... heimer's disease pathogenesis.
@ast
Suppression of InsP3 receptor- ...... heimer's disease pathogenesis.
@en
type
label
Suppression of InsP3 receptor- ...... heimer's disease pathogenesis.
@ast
Suppression of InsP3 receptor- ...... heimer's disease pathogenesis.
@en
prefLabel
Suppression of InsP3 receptor- ...... heimer's disease pathogenesis.
@ast
Suppression of InsP3 receptor- ...... heimer's disease pathogenesis.
@en
P2093
P2860
P50
P1476
Suppression of InsP3 receptor- ...... zheimer's disease pathogenesis
@en
P2093
Don-On Daniel Mak
Dustin Shilling
Marioly Müller
P2860
P304
P356
10.1523/JNEUROSCI.5441-13.2014
P407
P577
2014-05-01T00:00:00Z