cDNA cloning of human retinoic acid-metabolizing enzyme (hP450RAI) identifies a novel family of cytochromes P450
about
Retinoic acid synthesis and functions in early embryonic developmentIdentification of the human cytochrome P450, P450RAI-2, which is predominantly expressed in the adult cerebellum and is responsible for all-trans-retinoic acid metabolismCraniosynostosis and multiple skeletal anomalies in humans and zebrafish result from a defect in the localized degradation of retinoic acidA novel human cytochrome P450, CYP26C1, involved in metabolism of 9-cis and all-trans isomers of retinoic acidRetinoid-binding proteins: mediators of retinoid actionTranscriptional co-operativity between distant retinoic acid response elements in regulation of Cyp26A1 inducibilityRemoval of LIF (leukemia inhibitory factor) results in increased vitamin A (retinol) metabolism to 4-oxoretinol in embryonic stem cellsThe discovery of new coding alleles of human CYP26A1 that are potentially defective in the metabolism of all-trans retinoic acid and their assessment in a recombinant cDNA expression systemLeukocyte homing, fate, and function are controlled by retinoic acideXtraembryonic ENdoderm (XEN) stem cells produce factors that activate heart formationCytochrome P450, CYP26AI, is expressed at low levels in human epidermal keratinocytes and is not retinoic acid-inducibleInduction of TIG3, a putative class II tumor suppressor gene, by retinoic acid in head and neck and lung carcinoma cells and its association with suppression of the transformed phenotypeHomology model of human retinoic acid metabolising enzyme cytochrome P450 26A1 (CYP26A1): active site architecture and ligand bindingRegulation of a highly specific retinoic acid-4-hydroxylase (CYP26A1) enzyme and all-trans-retinoic acid metabolism in human intestinal, liver, endothelial, and acute promyelocytic leukemia cellsThe retinoic acid-metabolizing enzyme, CYP26A1, is essential for normal hindbrain patterning, vertebral identity, and development of posterior structures.Metabolism and growth inhibition of four retinoids in head and neck squamous normal and malignant cells4-hydroxyretinoic acid, a novel substrate for human liver microsomal UDP-glucuronosyltransferase(s) and recombinant UGT2B7Arsenic as an endocrine disruptor: arsenic disrupts retinoic acid receptor-and thyroid hormone receptor-mediated gene regulation and thyroid hormone-mediated amphibian tail metamorphosisDynamic expression of retinoic acid-synthesizing and -metabolizing enzymes in the developing mouse inner ear.Mouse P450RAI (CYP26) expression and retinoic acid-inducible retinoic acid metabolism in F9 cells are regulated by retinoic acid receptor gamma and retinoid X receptor alphaContribution of cellular retinol-binding protein type 1 to retinol metabolism during mouse developmentRegulation of skeletal progenitor differentiation by the BMP and retinoid signaling pathwaysRapid birth-death evolution specific to xenobiotic cytochrome P450 genes in vertebratesRetinoic acid metabolism inhibition by 3-azolylmethyl-1H-indoles and 2, 3 or 5-(alpha-azolylbenzyl)-1H-indoles.Differential expression of chicken CYP26 in anterior versus posterior limb bud in response to retinoic acid.A comparison of the roles of peroxisome proliferator-activated receptor and retinoic acid receptor on CYP26 regulation.Expression and functional characterization of cytochrome P450 26A1, a retinoic acid hydroxylaseIdentification and developmental expression of the full complement of Cytochrome P450 genes in ZebrafishIdentification of conserved genes triggering puberty in European sea bass males (Dicentrarchus labrax) by microarray expression profiling.Cyp26b1 regulates retinoic acid-dependent signals in T cells and its expression is inhibited by transforming growth factor-β.Knockout of the Bcmo1 gene results in an inflammatory response in female lung, which is suppressed by dietary beta-carotene.Regulation of cytochrome P450 (CYP) genes by nuclear receptors.Liver-specific cytochrome P450 CYP2C22 is a direct target of retinoic acid and a retinoic acid-metabolizing enzyme in rat liver.Mechanism of inhibition of MMTV-neu and MMTV-wnt1 induced mammary oncogenesis by RARalpha agonist AM580.Retinoids in chemoprevention and differentiation therapy.Multiple retinoic acid response elements cooperate to enhance the inducibility of CYP26A1 gene expression in liverMetabolism and transactivation activity of 13,14-dihydroretinoic acid.Therapeutic potential of the inhibition of the retinoic acid hydroxylases CYP26A1 and CYP26B1 by xenobiotics.Orchestration of multiple arrays of signal cross-talk and combinatorial interactions for maturation and cell death: another vision of t(15;17) preleukemic blast and APL-cell maturation.Retinoic acid regulates sex-specific timing of meiotic initiation in mice.
P2860
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P2860
cDNA cloning of human retinoic acid-metabolizing enzyme (hP450RAI) identifies a novel family of cytochromes P450
description
1997 nî lūn-bûn
@nan
1997 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
cDNA cloning of human retinoic ...... vel family of cytochromes P450
@ast
cDNA cloning of human retinoic ...... vel family of cytochromes P450
@en
cDNA cloning of human retinoic ...... vel family of cytochromes P450
@en-gb
cDNA cloning of human retinoic ...... vel family of cytochromes P450
@nl
type
label
cDNA cloning of human retinoic ...... vel family of cytochromes P450
@ast
cDNA cloning of human retinoic ...... vel family of cytochromes P450
@en
cDNA cloning of human retinoic ...... vel family of cytochromes P450
@en-gb
cDNA cloning of human retinoic ...... vel family of cytochromes P450
@nl
prefLabel
cDNA cloning of human retinoic ...... vel family of cytochromes P450
@ast
cDNA cloning of human retinoic ...... vel family of cytochromes P450
@en
cDNA cloning of human retinoic ...... vel family of cytochromes P450
@en-gb
cDNA cloning of human retinoic ...... vel family of cytochromes P450
@nl
P2093
P356
P1476
cDNA cloning of human retinoic ...... vel family of cytochromes P450
@en
P2093
B Beckett-Jones
F J Dilworth
J Bonasoro
M Petkovich
P304
P356
10.1074/JBC.272.30.18538
P407
P577
1997-07-25T00:00:00Z