Identification of AML-1 and the (8;21) translocation protein (AML-1/ETO) as sequence-specific DNA-binding proteins: the runt homology domain is required for DNA binding and protein-protein interactions
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Functional and physical interactions between AML1 proteins and an ETS protein, MEF: implications for the pathogenesis of t(8;21)-positive leukemiasp68 (Ddx5) interacts with Runx2 and regulates osteoblast differentiationRoles of HIPK1 and HIPK2 in AML1- and p300-dependent transcription, hematopoiesis and blood vessel formationMolecular cloning and characterization of NF-IL3A, a transcriptional activator of the human interleukin-3 promoterPbx1 is a downstream target of Evi-1 in hematopoietic stem/progenitors and leukemic cellsThe AML1-MTG8 leukemic fusion protein forms a complex with a novel member of the MTG8(ETO/CDR) family, MTGR1The MYND motif is required for repression of basal transcription from the multidrug resistance 1 promoter by the t(8;21) fusion proteinMyb-related Schizosaccharomyces pombe cdc5p is structurally and functionally conserved in eukaryotes.ETO, a target of t(8;21) in acute leukemia, interacts with the N-CoR and mSin3 corepressorsIdentification of homeotic target genes in Drosophila melanogaster including nervy, a proto-oncogene homologue.Human glycosaminoglycan glucuronyltransferase I gene and a related processed pseudogene: genomic structure, chromosomal mapping and characterizationA WW domain-containing yes-associated protein (YAP) is a novel transcriptional co-activator.Runx2 (Cbfa1, AML-3) interacts with histone deacetylase 6 and represses the p21(CIP1/WAF1) promoterDisruption of the Cbfa2 gene causes necrosis and hemorrhaging in the central nervous system and blocks definitive hematopoiesisAlternative splicing and genomic structure of the AML1 gene involved in acute myeloid leukemiaAcute Myeloid Leukemia: A Concise ReviewEvolutionary origin and genomic organisation of runt-domain containing genes in arthropodsNovel Prognostic and Therapeutic Mutations in Acute Myeloid LeukemiaAML1 (CBFalpha2) cooperates with B cell-specific activating protein (BSAP/PAX5) in activation of the B cell-specific BLK gene promoterNuclear import and subnuclear localization of the proto-oncoprotein ETO (MTG8)Genomic structure and chromosomal localization of the human hepatocyte growth factor activator inhibitor type 1 and 2 genesAML1 interconnected pathways of leukemogenesisMutational analyses of the AML1 gene in patients with myelodysplastic syndromeRunx2: a master organizer of gene transcription in developing and maturing osteoblastsIdentification of two transcripts of AML1/ETO-fused gene in t(8;21) leukemic cells and expression of wild-type ETO gene in hematopoietic cellsRunt-related transcription factor 1 regulates luteinized hormone-induced prostaglandin-endoperoxide synthase 2 expression in rat periovulatory granulosa cellsAML1 is expressed in skeletal muscle and is regulated by innervationMutagenesis of the Runt domain defines two energetic hot spots for heterodimerization with the core binding factor beta subunitLymphoid enhancer factor-1 and beta-catenin inhibit Runx2-dependent transcriptional activation of the osteocalcin promoterHematopoiesis in the fetal liver is impaired by targeted mutagenesis of a gene encoding a non-DNA binding subunit of the transcription factor, polyomavirus enhancer binding protein 2/core binding factorConBind: motif-aware cross-species alignment for the identification of functional transcription factor binding sitesIdentification of the regions involved in DNA binding by the mouse PEBP2alpha protein.RUNX1 and its understudied role in breast cancerA novel gene, FGA7, is fused to RUNX1/AML1 in a t(4;21)(q28;q22) in a patient with T-cell acute lymphoblastic leukemia.A distinct epigenetic signature at targets of a leukemia protein.t(8;21)(q22;q22) Fusion proteins preferentially bind to duplicated AML1/RUNX1 DNA-binding sequences to differentially regulate gene expression.ChIP Display: novel method for identification of genomic targets of transcription factors.AML1/ETO oncoprotein is directed to AML1 binding regions and co-localizes with AML1 and HEB on its targets.Myeloperoxidase gene expression and regulation by myeloid cell growth factors in normal and leukemic cells.The RUNX2 cistrome in osteoblasts: characterization, down-regulation following differentiation, and relationship to gene expression.
P2860
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P2860
Identification of AML-1 and the (8;21) translocation protein (AML-1/ETO) as sequence-specific DNA-binding proteins: the runt homology domain is required for DNA binding and protein-protein interactions
description
1993 nî lūn-bûn
@nan
1993 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1993 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
name
Identification of AML-1 and th ...... d protein-protein interactions
@ast
Identification of AML-1 and th ...... d protein-protein interactions
@en
Identification of AML-1 and th ...... d protein-protein interactions
@en-gb
Identification of AML-1 and th ...... d protein-protein interactions
@nl
type
label
Identification of AML-1 and th ...... d protein-protein interactions
@ast
Identification of AML-1 and th ...... d protein-protein interactions
@en
Identification of AML-1 and th ...... d protein-protein interactions
@en-gb
Identification of AML-1 and th ...... d protein-protein interactions
@nl
prefLabel
Identification of AML-1 and th ...... d protein-protein interactions
@ast
Identification of AML-1 and th ...... d protein-protein interactions
@en
Identification of AML-1 and th ...... d protein-protein interactions
@en-gb
Identification of AML-1 and th ...... d protein-protein interactions
@nl
P2093
P2860
P3181
P356
P1476
Identification of AML-1 and th ...... d protein-protein interactions
@en
P2093
J R Downing
S W Hiebert
P2860
P304
P3181
P356
10.1128/MCB.13.10.6336
P407
P577
1993-10-01T00:00:00Z