Regulation of XIAP translation and induction by MDM2 following irradiation
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Could the eIF2α-Independent Translation Be the Achilles Heel of Cancer?Targeting IAP proteins in combination with radiotherapyNoscapine induced apoptosis via downregulation of survivin in human neuroblastoma cells having wild type or null p53p53-independent roles of MDM2 in NF-κB signaling: implications for cancer therapy, wound healing, and autoimmune diseasesTargeting p53 for Novel Anticancer Therapy.New frontiers in translational control of the cancer genomeCombination of BCL11A siRNA with vincristine increases the apoptosis of SUDHL6 cells.p53-Independent apoptosis by benzyl isothiocyanate in human breast cancer cells is mediated by suppression of XIAP expressionDysregulating IRES-dependent translation contributes to overexpression of oncogenic Aurora A Kinase.Translation of TRAF1 is regulated by IRES-dependent mechanism and stimulated by vincristine.The Mdm2-p53 relationship evolves: Mdm2 swings both ways as an oncogene and a tumor suppressor.MDM2 regulates hypoxic hypoxia-inducible factor 1α stability in an E3 ligase, proteasome, and PTEN-phosphatidylinositol 3-kinase-AKT-dependent manner.Distinct 5' UTRs regulate XIAP expression under normal growth conditions and during cellular stressIdentification of a new class of MDM2 inhibitor that inhibits growth of orthotopic pancreatic tumors in mice.The Expression of SIRT1 and DBC1 in Laryngeal and Hypopharyngeal Carcinomas.Suppression of p53 by Notch3 is mediated by Cyclin G1 and sustained by MDM2 and miR-221 axis in hepatocellular carcinomaInhibition of PI3K/mTOR overcomes nilotinib resistance in BCR-ABL1 positive leukemia cells through translational down-regulation of MDM2.Inhibition of MDM2 by nilotinib contributes to cytotoxicity in both Philadelphia-positive and negative acute lymphoblastic leukemiaStress-induced alternative splice forms of MDM2 and MDMX modulate the p53-pathway in distinct waysInhibition of MDM2 homodimerization by XIAP IRES stabilizes MDM2, influencing cancer cell survival.Mdm2 promotes myogenesis through the ubiquitination and degradation of CCAAT/enhancer-binding protein β.MDM2 regulates MYCN mRNA stabilization and translation in human neuroblastoma cellsCrosstalk between MYCN and MDM2-p53 signal pathways regulates tumor cell growth and apoptosis in neuroblastomaMDM2 regulates vascular endothelial growth factor mRNA stabilization in hypoxiaIRES-mediated translation of cellular messenger RNA operates in eIF2α- independent manner during stress.Phenethyl isothiocyanate suppresses inhibitor of apoptosis family protein expression in prostate cancer cells in culture and in vivo.The Role of Translational Regulation in Survival after Radiation Damage; an Opportunity for Proteomics Analysis.Tumor suppressor PDCD4 represses internal ribosome entry site-mediated translation of antiapoptotic proteins and is regulated by S6 kinase 2.Discovery of Dual Inhibitors of MDM2 and XIAP for Cancer Treatment.Ribosome biogenesis dysfunction leads to p53-mediated apoptosis and goblet cell differentiation of mouse intestinal stem/progenitor cellsRNA-binding protein HuR mediates cytoprotection through stimulation of XIAP translation.Methylation of RASSF1A gene promoter is regulated by p53 and DAXX.Vitamin D directly regulates Mdm2 gene expression in osteoblasts.BIRC3 is a novel driver of therapeutic resistance in Glioblastoma.Triptolide inhibits MDM2 and induces apoptosis in acute lymphoblastic leukemia cells through a p53-independent pathway.Premenopausal Obesity and Breast Cancer Growth Rates in a Rodent ModelThe MDM2-p53 pathway revisitedXIAP inhibits autophagy via XIAP-Mdm2-p53 signalling.A network of substrates of the E3 ubiquitin ligases MDM2 and HUWE1 control apoptosis independently of p53.IAP proteins as targets for drug development in oncology
P2860
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P2860
Regulation of XIAP translation and induction by MDM2 following irradiation
description
2009 nî lūn-bûn
@nan
2009 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Regulation of XIAP translation and induction by MDM2 following irradiation
@ast
Regulation of XIAP translation and induction by MDM2 following irradiation
@en
Regulation of XIAP translation and induction by MDM2 following irradiation
@en-gb
Regulation of XIAP translation and induction by MDM2 following irradiation
@nl
type
label
Regulation of XIAP translation and induction by MDM2 following irradiation
@ast
Regulation of XIAP translation and induction by MDM2 following irradiation
@en
Regulation of XIAP translation and induction by MDM2 following irradiation
@en-gb
Regulation of XIAP translation and induction by MDM2 following irradiation
@nl
prefLabel
Regulation of XIAP translation and induction by MDM2 following irradiation
@ast
Regulation of XIAP translation and induction by MDM2 following irradiation
@en
Regulation of XIAP translation and induction by MDM2 following irradiation
@en-gb
Regulation of XIAP translation and induction by MDM2 following irradiation
@nl
P2093
P2860
P3181
P1433
P1476
Regulation of XIAP translation and induction by MDM2 following irradiation
@en
P2093
Donald L Durden
Hongying Zhang
Muxiang Zhou
Ningxi Zhu
P2860
P304
P3181
P356
10.1016/J.CCR.2009.03.002
P407
P577
2009-05-05T00:00:00Z