A Cullin3-KLHL20 Ubiquitin ligase-dependent pathway targets PML to potentiate HIF-1 signaling and prostate cancer progression
about
Update on the Kelch-like (KLHL) gene familyThe genetic architecture of adaptations to high altitude in EthiopiaThe epigenetic regulator UHRF1 promotes ubiquitination-mediated degradation of the tumor-suppressor protein promyelocytic leukemia proteinUbiquitylation-dependent localization of PLK1 in mitosisCullin 3 Ubiquitin Ligases in Cancer Biology: Functions and Therapeutic ImplicationsCul3-KLHL20 ubiquitin ligase: physiological functions, stress responses, and disease implicationsThe function, regulation and therapeutic implications of the tumor suppressor protein, PMLCullin family proteins and tumorigenesis: genetic association and molecular mechanismsGenetically engineered mouse models for functional studies of SKP1-CUL1-F-box-protein (SCF) E3 ubiquitin ligasesKelch proteins: emerging roles in skeletal muscle development and diseases.Cullin3-KLHL15 ubiquitin ligase mediates CtIP protein turnover to fine-tune DNA-end resectionKelch-like ECT2-interacting protein KLEIP regulates late-stage pulmonary maturation via Hif-2α in mice.Global discovery of high-NaCl-induced changes of protein phosphorylationRegulation of with-no-lysine kinase signaling by Kelch-like proteins.A nucleolin-DNMT1 regulatory axis in acute myeloid leukemogenesis.PML-mediated signaling and its role in cancer stem cells.Crystal structure of KLHL3 in complex with Cullin3Expression of the RNA helicase DDX3 and the hypoxia response in breast cancerMitogen-activated protein kinase extracellular signal-regulated kinase 2 phosphorylates and promotes Pin1 protein-dependent promyelocytic leukemia protein turnover.Identification of RNF168 as a PML nuclear body regulatorPeptidyl Prolyl Isomerase PIN1 Directly Binds to and Stabilizes Hypoxia-Inducible Factor-1α.Negative regulation of the stability and tumor suppressor function of Fbw7 by the Pin1 prolyl isomerase.PML represses lung cancer metastasis by suppressing the nuclear EGFR-mediated transcriptional activation of MMP2.The role of PML ubiquitination in human malignancies.Post-translational modifications of PML: consequences and implications.Cullin3 promotes breast cancer cells metastasis and epithelial-mesenchymal transition by targeting BRMS1 for degradation.Proline isomer-specific antibodies reveal the early pathogenic tau conformation in Alzheimer's disease.New Strategies to Direct Therapeutic Targeting of PML to Treat CancersTumour suppressor death-associated protein kinase targets cytoplasmic HIF-1α for Th17 suppression.Early phosphoproteomic changes in the mouse spleen during deoxynivalenol-induced ribotoxic stressThe emerging family of CULLIN3-RING ubiquitin ligases (CRL3s): cellular functions and disease implications.SENP1 deSUMOylates and regulates Pin1 protein activity and cellular functionTranslational control of PML contributes to TNFα-induced apoptosis of MCF7 breast cancer cells and decreased angiogenesis in HUVECs.Ubiquitin at the crossroad of cell death and survival.Regulation of the tumor suppressor PML by sequential post-translational modifications.PML Degradation: Multiple Ways to Eliminate PML.Differential Roles of PML Isoforms.The functions and regulations of DAPK in cancer metastasis.PML tumour suppression and beyond: therapeutic implications.The isomerase PIN1 controls numerous cancer-driving pathways and is a unique drug target.
P2860
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P2860
A Cullin3-KLHL20 Ubiquitin ligase-dependent pathway targets PML to potentiate HIF-1 signaling and prostate cancer progression
description
2011 nî lūn-bûn
@nan
2011 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
A Cullin3-KLHL20 Ubiquitin lig ...... nd prostate cancer progression
@ast
A Cullin3-KLHL20 Ubiquitin lig ...... nd prostate cancer progression
@en
A Cullin3-KLHL20 Ubiquitin lig ...... nd prostate cancer progression
@en-gb
A Cullin3-KLHL20 Ubiquitin lig ...... nd prostate cancer progression
@nl
type
label
A Cullin3-KLHL20 Ubiquitin lig ...... nd prostate cancer progression
@ast
A Cullin3-KLHL20 Ubiquitin lig ...... nd prostate cancer progression
@en
A Cullin3-KLHL20 Ubiquitin lig ...... nd prostate cancer progression
@en-gb
A Cullin3-KLHL20 Ubiquitin lig ...... nd prostate cancer progression
@nl
prefLabel
A Cullin3-KLHL20 Ubiquitin lig ...... nd prostate cancer progression
@ast
A Cullin3-KLHL20 Ubiquitin lig ...... nd prostate cancer progression
@en
A Cullin3-KLHL20 Ubiquitin lig ...... nd prostate cancer progression
@en-gb
A Cullin3-KLHL20 Ubiquitin lig ...... nd prostate cancer progression
@nl
P2093
P3181
P1433
P1476
A Cullin3-KLHL20 Ubiquitin lig ...... nd prostate cancer progression
@en
P2093
Cheng-Ta Chiang
Chin-Hsien Tsai
Chun-Hau Chen
Chun-Kai Lai
De-Leung Gu
Hsiang-Ching Chung
Hsin-Yi Chen
Hsiu-Ming Shih
Kun Ping Lu
Li-Ting Lu
P304
P3181
P356
10.1016/J.CCR.2011.07.008
P407
P577
2011-08-16T00:00:00Z