PEX12 encodes an integral membrane protein of peroxisomes
about
Mutation in PEX16 is causal in the peroxisome-deficient Zellweger syndrome of complementation group D.Human PEX19: cDNA cloning by functional complementation, mutation analysis in a patient with Zellweger syndrome, and potential role in peroxisomal membrane assemblyPEX12 interacts with PEX5 and PEX10 and acts downstream of receptor docking in peroxisomal matrix protein importMolecular anatomy of the peroxin Pex12p: ring finger domain is essential for Pex12p function and interacts with the peroxisome-targeting signal type 1-receptor Pex5p and a ring peroxin, Pex10pTopogenesis of peroxisomal membrane protein requires a short, positively charged intervening-loop sequence and flanking hydrophobic segments. study using human membrane protein PMP34Identification of PEX10, the gene defective in complementation group 7 of the peroxisome-biogenesis disordersClofibrate-inducible, 28-kDa peroxisomal integral membrane protein is encoded by PEX11PEX12, the pathogenic gene of group III Zellweger syndrome: cDNA cloning by functional complementation on a CHO cell mutant, patient analysis, and characterization of PEX12pPeroxisome targeting signal type 1 (PTS1) receptor is involved in import of both PTS1 and PTS2: studies with PEX5-defective CHO cell mutants.Phenotype-genotype relationships in complementation group 3 of the peroxisome-biogenesis disordersThe peroxin pex3p initiates membrane assembly in peroxisome biogenesisHuman PEX1 cloned by functional complementation on a CHO cell mutant is responsible for peroxisome-deficient Zellweger syndrome of complementation group IThe peroxin Pex14p. cDNA cloning by functional complementation on a Chinese hamster ovary cell mutant, characterization, and functional analysisNovel mutations in the PEX12 gene of patients with a peroxisome biogenesis disorderIdentification of novel mutations and sequence variation in the Zellweger syndrome spectrum of peroxisome biogenesis disordersTopogenesis and homeostasis of fatty acyl-CoA reductase 1Peroxisome biogenesis and peroxisome biogenesis disorders.Peroxisome biogenesis and human peroxisome-deficiency disorders.Protein transport into peroxisomes: Knowns and unknowns.Distinct modes of ubiquitination of peroxisome-targeting signal type 1 (PTS1) receptor Pex5p regulate PTS1 protein import.Intracellular localization, function, and dysfunction of the peroxisome-targeting signal type 2 receptor, Pex7p, in mammalian cells.A novel mutation in the PEX12 gene causing a peroxisomal biogenesis disorder.Disruption of the interaction of the longer isoform of Pex5p, Pex5pL, with Pex7p abolishes peroxisome targeting signal type 2 protein import in mammals. Study with a novel Pex5-impaired Chinese hamster ovary cell mutant.Newly identified Chinese hamster ovary cell mutants are defective in biogenesis of peroxisomal membrane vesicles (Peroxisomal ghosts), representing a novel complementation group in mammals.Diagnosis and follow-up of a case of peroxisomal disorder with peroxisomal mosaicism
P2860
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P2860
PEX12 encodes an integral membrane protein of peroxisomes
description
1997 nî lūn-bûn
@nan
1997 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
PEX12 encodes an integral membrane protein of peroxisomes
@ast
PEX12 encodes an integral membrane protein of peroxisomes
@en
PEX12 encodes an integral membrane protein of peroxisomes
@en-gb
PEX12 encodes an integral membrane protein of peroxisomes
@nl
type
label
PEX12 encodes an integral membrane protein of peroxisomes
@ast
PEX12 encodes an integral membrane protein of peroxisomes
@en
PEX12 encodes an integral membrane protein of peroxisomes
@en-gb
PEX12 encodes an integral membrane protein of peroxisomes
@nl
prefLabel
PEX12 encodes an integral membrane protein of peroxisomes
@ast
PEX12 encodes an integral membrane protein of peroxisomes
@en
PEX12 encodes an integral membrane protein of peroxisomes
@en-gb
PEX12 encodes an integral membrane protein of peroxisomes
@nl
P2860
P356
P1433
P1476
PEX12 encodes an integral membrane protein of peroxisomes
@en
P2093
P2860
P2888
P356
10.1038/NG1197-265
P407
P577
1997-11-01T00:00:00Z
P5875
P6179
1044531593