The 2.2 A crystal structure of the Ras-binding domain of the serine/threonine kinase c-Raf1 in complex with Rap1A and a GTP analogue
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Structure of Cdc42 in complex with the GTPase-binding domain of the 'Wiskott-Aldrich syndrome' proteinStructure of the small G protein Cdc42 bound to the GTPase-binding domain of ACKRA-GEF, a novel Rap1A guanine nucleotide exchange factor containing a Ras/Rap1A-associating domain, is conserved between nematode and humansRA-GEF-1, a guanine nucleotide exchange factor for Rap1, is activated by translocation induced by association with Rap1*GTP and enhances Rap1-dependent B-Raf activationThe complex of Arl2-GTP and PDE delta: from structure to functionThe RAP1 guanine nucleotide exchange factor Epac2 couples cyclic AMP and Ras signals at the plasma membraneStructural basis of the interaction between RalA and Sec5, a subunit of the sec6/8 complexThe Cdc42/Rac interactive binding region motif of the Wiskott Aldrich syndrome protein (WASP) is necessary but not sufficient for tight binding to Cdc42 and structure formationRas/Rap effector specificity determined by charge reversalRaf family kinases: old dogs have learned new tricksIntroduction of p130cas signaling complex formation upon integrin-mediated cell adhesion: a role for Src family kinasesProtein binding and signaling properties of RIN1 suggest a unique effector functionIdentification of the Rho-binding domain of p160ROCK, a Rho-associated coiled-coil containing protein kinaseBinding of c-Raf1 kinase to a conserved acidic sequence within the carboxyl-terminal region of the HIV-1 Nef proteinHGF receptor associates with the anti-apoptotic protein BAG-1 and prevents cell deathThe RafC1 cysteine-rich domain contains multiple distinct regulatory epitopes which control Ras-dependent Raf activationRGS14 is a novel Rap effector that preferentially regulates the GTPase activity of galphaoStructural basis for the recognition of regulatory subunits by the catalytic subunit of protein phosphatase 1Crystal structures of the small G protein Rap2A in complex with its substrate GTP, with GDP and with GTPgammaS.Insulin regulates the dynamic balance between Ras and Rap1 signaling by coordinating the assembly states of the Grb2-SOS and CrkII-C3G complexes.Activation of the Raf/MAP kinase cascade by the Ras-related protein TC21 is required for the TC21-mediated transformation of NIH 3T3 cells.The RAS effector RIN1 directly competes with RAF and is regulated by 14-3-3 proteins.Glucocorticoid-induced leucine zipper inhibits the Raf-extracellular signal-regulated kinase pathway by binding to Raf-1The strength of interaction at the Raf cysteine-rich domain is a critical determinant of response of Raf to Ras family small GTPasesRit contributes to nerve growth factor-induced neuronal differentiation via activation of B-Raf-extracellular signal-regulated kinase and p38 mitogen-activated protein kinase cascadesStructural basis of the membrane-targeting and unmasking mechanisms of the radixin FERM domainThe solution structure of the Raf-1 cysteine-rich domain: a novel ras and phospholipid binding siteInteraction of activated Ras with Raf-1 alone may be sufficient for transformation of rat2 cellsRheb interacts with Raf-1 kinase and may function to integrate growth factor- and protein kinase A-dependent signals.Phosphorylation-induced conformational changes in Rap1b: allosteric effects on switch domains and effector loopIdentification of Rap1 as a target for the Crk SH3 domain-binding guanine nucleotide-releasing factor C3GSwitches, latches, and amplifiers: common themes of G proteins and molecular motorsAutoregulation of the Raf-1 serine/threonine kinaseRab3 reversibly recruits rabphilin to synaptic vesicles by a mechanism analogous to raf recruitment by rasAblation of BRaf impairs neuronal differentiation in the postnatal hippocampus and cerebellumRas conformational switching: simulating nucleotide-dependent conformational transitions with accelerated molecular dynamicsStructure of a Ran-binding domain complexed with Ran bound to a GTP analogue: implications for nuclear transportNucleotide binding to the G12V-mutant of Cdc42 investigated by X-ray diffraction and fluorescence spectroscopy: Two different nucleotide states in one crystalStructure of the small G protein Rap2 in a non-catalytic complex with GTPStructure of GATE-16, membrane transport modulator and mammalian ortholog of autophagocytosis factor Aut7p
P2860
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P2860
The 2.2 A crystal structure of the Ras-binding domain of the serine/threonine kinase c-Raf1 in complex with Rap1A and a GTP analogue
description
1995 nî lūn-bûn
@nan
1995 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
The 2.2 A crystal structure of ...... with Rap1A and a GTP analogue
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The 2.2 A crystal structure of ...... with Rap1A and a GTP analogue
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The 2.2 A crystal structure of ...... with Rap1A and a GTP analogue
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The 2.2 A crystal structure of ...... with Rap1A and a GTP analogue
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label
The 2.2 A crystal structure of ...... with Rap1A and a GTP analogue
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The 2.2 A crystal structure of ...... with Rap1A and a GTP analogue
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The 2.2 A crystal structure of ...... with Rap1A and a GTP analogue
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The 2.2 A crystal structure of ...... with Rap1A and a GTP analogue
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The 2.2 A crystal structure of ...... with Rap1A and a GTP analogue
@ast
The 2.2 A crystal structure of ...... with Rap1A and a GTP analogue
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The 2.2 A crystal structure of ...... with Rap1A and a GTP analogue
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The 2.2 A crystal structure of ...... with Rap1A and a GTP analogue
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P2093
P3181
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The 2.2 A crystal structure of ...... with Rap1A and a GTP analogue
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P2093
P2888
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P3181
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10.1038/375554A0
P407
P577
1995-06-15T00:00:00Z
P6179
1023663019