Rheb interacts with Raf-1 kinase and may function to integrate growth factor- and protein kinase A-dependent signals.
about
Identification and characterization of RHEBL1, a novel member of Ras family, which activates transcriptional activities of NF-kappa BIdentification of dominant negative mutants of Rheb GTPase and their use to implicate the involvement of human Rheb in the activation of p70S6KRaf family kinases: old dogs have learned new tricksSignaling by target of rapamycin proteins in cell growth controlMeaningful relationships: the regulation of the Ras/Raf/MEK/ERK pathway by protein interactionsRegulation of TOR by small GTPasesRheb GTPase is a direct target of TSC2 GAP activity and regulates mTOR signalingThe Saccharomyces cerevisiae Rheb G-protein is involved in regulating canavanine resistance and arginine uptake.Involvement of phosphatidylinositol 3-kinase, but not RalGDS, in TC21/R-Ras2-mediated transformationRegulation of B-Raf kinase activity by tuberin and Rheb is mammalian target of rapamycin (mTOR)-independentLoss of tuberous sclerosis complex 1 (Tsc1) expression results in increased Rheb/S6K pathway signaling important for astrocyte cell size regulationNon-canonical functions of the tuberous sclerosis complex-Rheb signalling axisThe function of activity-regulated genes in the nervous system.Optics clustered to output unique solutions: a multi-laser facility for combined single molecule and ensemble microscopy.Rheb promotes cell growth as a component of the insulin/TOR signalling network.Insight into the role of mTOR and metabolism in T cells reveals new potential approaches to preventing graft rejection.The kinase mTOR regulates the differentiation of helper T cells through the selective activation of signaling by mTORC1 and mTORC2.Deletion of the Aspergillus fumigatus gene encoding the Ras-related protein RhbA reduces virulence in a model of Invasive pulmonary aspergillosis.mTORC1 and mTORC2 selectively regulate CD8⁺ T cell differentiation.Constitutively active Rheb induces oncogenic transformation.The mammalian target of rapamycin: linking T cell differentiation, function, and metabolismRegulation of immune responses by mTOR.Rheb signaling and tumorigenesis: mTORC1 and new horizons.Cyclic-GMP-dependent protein kinase inhibits the Ras/Mitogen-activated protein kinase pathway.Induction of interleukin-8 by ozone is mediated by tyrosine kinase and protein kinase A, but not by protein kinase C.Rapid activation and nuclear translocation of mitogen-activated protein kinases in response to physiological concentration of glucose in the MIN6 pancreatic beta cell line.Dual targeting of the PI3K/Akt/mTOR pathway as an antitumor strategy in Waldenstrom macroglobulinemia.Selective abrogation of BiP/GRP78 blunts activation of NF-κB through the ATF6 branch of the UPR: involvement of C/EBPβ and mTOR-dependent dephosphorylation of Akt.Loss of Rhb1, a Rheb-related GTPase in fission yeast, causes growth arrest with a terminal phenotype similar to that caused by nitrogen starvation.Rheb G-Proteins and the Activation of mTORC1.Rheb is in a high activation state and inhibits B-Raf kinase in mammalian cells.The RAF family: an expanding network of post-translational controls and protein-protein interactions.mTORC1 Promotes T-bet Phosphorylation To Regulate Th1 Differentiation.An oncogenic mutant of RHEB, RHEB Y35N, exhibits an altered interaction with BRAF resulting in cancer transformation.
P2860
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P2860
Rheb interacts with Raf-1 kinase and may function to integrate growth factor- and protein kinase A-dependent signals.
description
1997 nî lūn-bûn
@nan
1997 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Rheb interacts with Raf-1 kina ...... ein kinase A-dependent signals
@nl
Rheb interacts with Raf-1 kina ...... in kinase A-dependent signals.
@ast
Rheb interacts with Raf-1 kina ...... in kinase A-dependent signals.
@en
type
label
Rheb interacts with Raf-1 kina ...... ein kinase A-dependent signals
@nl
Rheb interacts with Raf-1 kina ...... in kinase A-dependent signals.
@ast
Rheb interacts with Raf-1 kina ...... in kinase A-dependent signals.
@en
prefLabel
Rheb interacts with Raf-1 kina ...... ein kinase A-dependent signals
@nl
Rheb interacts with Raf-1 kina ...... in kinase A-dependent signals.
@ast
Rheb interacts with Raf-1 kina ...... in kinase A-dependent signals.
@en
P2860
P356
P1476
Rheb interacts with Raf-1 kina ...... in kinase A-dependent signals.
@en
P2093
P2860
P304
P356
10.1128/MCB.17.2.921
P407
P577
1997-02-01T00:00:00Z