A new family of orphan G protein-coupled receptors predominantly expressed in the brain
about
GPR37 and GPR37L1 are receptors for the neuroprotective and glioprotective factors prosaptide and prosaposinThe protein interacting with C-kinase (PICK1) interacts with and attenuates parkin-associated endothelial-like (PAEL) receptor-mediated cell deathDrug Discovery Opportunities at the Endothelin B Receptor-Related Orphan G Protein-Coupled Receptors, GPR37 and GPR37L1The protective role of prosaposin and its receptors in the nervous systemPrecocious cerebellum development and improved motor functions in mice lacking the astrocyte cilium-, patched 1-associated Gpr37l1 receptorSelective targeting and inducible destruction of human cancer cells by retroviruses with envelope proteins bearing short peptide ligandsHunting for the function of orphan GPCRs - beyond the search for the endogenous ligand.Primary Cilia in the Murine Cerebellum and in Mutant Models of Medulloblastoma.Astroglia as a cellular target for neuroprotection and treatment of neuro-psychiatric disorders.The Parkinson's disease-associated GPR37 receptor-mediated cytotoxicity is controlled by its intracellular cysteine-rich domain.GPR37 surface expression enhancement via N-terminal truncation or protein-protein interactionsMetalloprotease cleavage of the N terminus of the orphan G protein-coupled receptor GPR37L1 reduces its constitutive activity.Orphan receptor ligand discovery by pickpocketing pharmacological neighbors.G protein-coupled receptor 37-like 1 modulates astrocyte glutamate transporters and neuronal NMDA receptors and is neuroprotective in ischemia.The role of parkinson's disease-associated receptor GPR37 in the hippocampus: functional interplay with the adenosinergic system.GPR37L1 modulates seizure susceptibility: Evidence from mouse studies and analyses of a human GPR37L1 variant.Mice lacking Gpr37 exhibit decreased expression of the myelin-associated glycoprotein MAG and increased susceptibility to demyelination.Orphan receptor GPR37L1 contributes to the sexual dimorphism of central cardiovascular control.
P2860
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P2860
A new family of orphan G protein-coupled receptors predominantly expressed in the brain
description
1998 nî lūn-bûn
@nan
1998 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի մարտին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
A new family of orphan G protein-coupled receptors predominantly expressed in the brain
@ast
A new family of orphan G protein-coupled receptors predominantly expressed in the brain
@en
A new family of orphan G protein-coupled receptors predominantly expressed in the brain
@en-gb
A new family of orphan G protein-coupled receptors predominantly expressed in the brain
@nl
type
label
A new family of orphan G protein-coupled receptors predominantly expressed in the brain
@ast
A new family of orphan G protein-coupled receptors predominantly expressed in the brain
@en
A new family of orphan G protein-coupled receptors predominantly expressed in the brain
@en-gb
A new family of orphan G protein-coupled receptors predominantly expressed in the brain
@nl
prefLabel
A new family of orphan G protein-coupled receptors predominantly expressed in the brain
@ast
A new family of orphan G protein-coupled receptors predominantly expressed in the brain
@en
A new family of orphan G protein-coupled receptors predominantly expressed in the brain
@en-gb
A new family of orphan G protein-coupled receptors predominantly expressed in the brain
@nl
P2093
P2860
P921
P1433
P1476
A new family of orphan G protein-coupled receptors predominantly expressed in the brain
@en
P2093
P2860
P356
10.1016/S0014-5793(98)00170-7
P407
P577
1998-03-13T00:00:00Z