Orphan receptor ligand discovery by pickpocketing pharmacological neighbors. - Test2 - elhamkhani - TriplyDB

Orphan receptor ligand discovery by pickpocketing pharmacological neighbors.

Orphan receptor ligand discovery by pickpocketing pharmacological neighbors.

http://www.wikidata.org/entity/Q42112336

about

Analysis of drug binding pockets and repurposing opportunities for twelve essential enzymes of ESKAPE pathogens How Ligands Illuminate GPCR Molecular Pharmacology.New Insights into PI3K Inhibitor Design using X-ray Structures of PI3Kα Complexed with a Potent Lead Compound.G protein-coupled receptors not currently in the spotlight: free fatty acid receptor 2 and GPR35.Discovery of new GPCR ligands to illuminate new biology.A Structural Framework for GPCR Chemogenomics: What's In a Residue Number?Enhancing Structure Prediction and Design of Soluble and Membrane Proteins with Explicit Solvent-Protein Interactions.Receptor pharmacology: Picking the pocketome for orphan receptor ligands.Orphan receptor GPR37L1 contributes to the sexual dimorphism of central cardiovascular control.Expression map of 78 brain-expressed mouse orphan GPCRs provides a translational resource for neuropsychiatric research The Orphan Receptor GPR35 Contributes to Angiotensin II-Induced Hypertension and Cardiac Dysfunction in Mice

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P2860

Orphan receptor ligand discovery by pickpocketing pharmacological neighbors.

http://www.wikidata.org/entity/Q42112336

description

2016 nî lūn-bûn

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2016年の論文

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2016年論文

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2016年論文

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2016年論文

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2016年論文

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2016年論文

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2016年论文

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2016年论文

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2016年论文

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name

Orphan receptor ligand discovery by pickpocketing pharmacological neighbors.

@en

Orphan receptor ligand discovery by pickpocketing pharmacological neighbors.

@nl

type

label

Orphan receptor ligand discovery by pickpocketing pharmacological neighbors.

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Orphan receptor ligand discovery by pickpocketing pharmacological neighbors.

@nl

prefLabel

Orphan receptor ligand discovery by pickpocketing pharmacological neighbors.

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Orphan receptor ligand discovery by pickpocketing pharmacological neighbors.

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Nature Chemical Biology

P1476

Orphan receptor ligand discovery by pickpocketing pharmacological neighbors.

@en

P2093

Andrey V Ilatovskiy

http://www.w3.org/2001/XMLSchema#string

Fiona M McRobb

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James L J Coleman

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R Peter Riek

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P2860

A new family of orphan G protein-coupled receptors predominantly expressed in the brain

International Union of Basic and Clinical Pharmacology. LXXXVIII. G protein-coupled receptor list: recommendations for new pairings with cognate ligands

Predicting new molecular targets for known drugs

Drug Discovery Opportunities at the Endothelin B Receptor-Related Orphan G Protein-Coupled Receptors, GPR37 and GPR37L1

The ChEMBL bioactivity database: an update

Activation mechanism of endothelin ETB receptor by endothelin-1

Generic GPCR residue numbers - aligning topology maps while minding the gaps

Melanocortin Receptor Agonists Facilitate Oxytocin-Dependent Partner Preference Formation in the Prairie Vole

Exhaustive matching of the entire protein sequence database

The Concise Guide to PHARMACOLOGY 2015/16: G protein-coupled receptors

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235-242

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scholarly article

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10.1038/NCHEMBIO.2266

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2

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13

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Alastair G Stewart

Robert M Graham

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2016-12-19T00:00:00Z

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1048068891

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27992882

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5247308

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