Crystal structure of an antagonist mutant of human growth hormone, G120R, in complex with its receptor at 2.9 A resolution
about
A common model for cytokine receptor activation: combined scissor-like rotation and self-rotation of receptor dimer induced by class I cytokineCrystallographic evidence for preformed dimers of erythropoietin receptor before ligand activationHormone interactions to Leu-rich repeats in the gonadotropin receptors. I. Analysis of Leu-rich repeats of human luteinizing hormone/chorionic gonadotropin receptor and follicle-stimulating hormone receptor.Structure collisions between interacting proteinsComputational alanine scanning with linear scaling semiempirical quantum mechanical methods.Two wrongs can make a right: dimers of prolactin and growth hormone receptor antagonists behave as agonistsThermodynamics-based drug design: strategies for inhibiting protein-protein interactions.Comprehensive analysis of loops at protein-protein interfaces for macrocycle design.Interleukin-6: structure-function relationships.Optimization of CD4/gp120 inhibitors by thermodynamic-guided alanine-scanning mutagenesisActivation of growth hormone receptors by growth hormone and growth hormone antagonist dimers: insights into receptor triggering.Single-residue posttranslational modification sites at the N-terminus, C-terminus or in-between: To be or not to be exposed for enzyme accessComputational stabilization of human growth hormone.Growth hormone (GH)-independent dimerization of GH receptor by a leucine zipper results in constitutive activation.Allosteric Dynamic Control of Binding.Development of a novel ligand that activates JAK2/STAT5 signaling through a heterodimer of prolactin receptor and growth hormone receptor.Site2 binding energetics of the regulatory step of growth hormone-induced receptor homodimerization.LIF receptor-gp130 interaction investigated by homology modeling: implications for LIF binding.A common polymorphism of the growth hormone receptor is associated with increased responsiveness to growth hormone.HBPred: a tool to identify growth hormone-binding proteins.
P2860
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P248
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P2860
Crystal structure of an antagonist mutant of human growth hormone, G120R, in complex with its receptor at 2.9 A resolution
description
1996 nî lūn-bûn
@nan
1996 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
name
Crystal structure of an antago ...... s receptor at 2.9 A resolution
@ast
Crystal structure of an antago ...... s receptor at 2.9 A resolution
@en
Crystal structure of an antago ...... s receptor at 2.9 A resolution
@en-gb
Crystal structure of an antago ...... s receptor at 2.9 A resolution
@nl
type
label
Crystal structure of an antago ...... s receptor at 2.9 A resolution
@ast
Crystal structure of an antago ...... s receptor at 2.9 A resolution
@en
Crystal structure of an antago ...... s receptor at 2.9 A resolution
@en-gb
Crystal structure of an antago ...... s receptor at 2.9 A resolution
@nl
prefLabel
Crystal structure of an antago ...... s receptor at 2.9 A resolution
@ast
Crystal structure of an antago ...... s receptor at 2.9 A resolution
@en
Crystal structure of an antago ...... s receptor at 2.9 A resolution
@en-gb
Crystal structure of an antago ...... s receptor at 2.9 A resolution
@nl
P2093
P2860
P921
P356
P1476
Crystal structure of an antago ...... s receptor at 2.9 A resolution
@en
P2093
D Milligan
G Norstedt
L B Giebel
M Sundström
T Lundqvist
P2860
P304
P356
10.1074/JBC.271.50.32197
P407
P577
1996-12-13T00:00:00Z