Dimerization of the transmembrane domain of Integrin alphaIIb subunit in cell membranes
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Disruption of the integrin alphaLbeta2 transmembrane domain interface by beta2 Thr-686 mutation activates alphaLbeta2 and promotes micro-clustering of the alphaL subunitsThe structure of the integrin alphaIIbbeta3 transmembrane complex explains integrin transmembrane signallingStructural organization and interactions of transmembrane domains in tetraspanin proteinsKinetics of peptide folding in lipid membranesStructural Organization of FtsB, a Transmembrane Protein of the Bacterial DivisomeSpecific heteromeric association of four transmembrane peptides derived from platelet glycoprotein Ib-IX complexPlatelet integrin alpha(IIb)beta(3): activation mechanismsIsolated Toll-like receptor transmembrane domains are capable of oligomerizationThree-dimensional structures by two-dimensional vibrational spectroscopy.Protein engineering methods applied to membrane protein targets.Data-driven docking for the study of biomolecular complexes.Transmembrane homodimerization of receptor-like protein tyrosine phosphatases.Activation of the p75 neurotrophin receptor through conformational rearrangement of disulphide-linked receptor dimersConsensus motif for integrin transmembrane helix associationA push-pull mechanism for regulating integrin function.Disrupting integrin transmembrane domain heterodimerization increases ligand binding affinity, not valency or clustering.The final steps of integrin activation: the end gameSpecificity for homooligomer versus heterooligomer formation in integrin transmembrane helicesA Gly-zipper motif mediates homodimerization of the transmembrane domain of the mitochondrial kinase ADCK3.Tests of integrin transmembrane domain homo-oligomerization during integrin ligand binding and signalingP-selectin glycoprotein ligand-1 forms dimeric interactions with E-selectin but monomeric interactions with L-selectin on cell surfaces.L-selectin transmembrane and cytoplasmic domains are monomeric in membranes.Molecular determinants and thermodynamics of the amyloid precursor protein transmembrane domain implicated in Alzheimer's disease.CW-EPR studies revealed different motional properties and oligomeric states of the integrin β1a transmembrane domain in detergent micelles or liposomesTransmembrane domain oligomerization propensity determined by ToxR assay.Reconstruction of integrin activation.The role of NDR1 in pathogen perception and plant defense signalingJuxtamembrane contribution to transmembrane signaling.Residue-specific structures and membrane locations of pH-low insertion peptide by solid-state nuclear magnetic resonanceCritical role of the first transmembrane domain of Cx26 in regulating oligomerization and functionPrediction, refinement, and persistency of transmembrane helix dimers in lipid bilayers using implicit and explicit solvent/lipid representations: microsecond molecular dynamics simulations of ErbB1/B2 and EphA1.Localized lipid packing of transmembrane domains impedes integrin clustering.Transmembrane domains of the syndecan family of growth factor coreceptors display a hierarchy of homotypic and heterotypic interactions.The association of polar residues in the DAP12 homodimer: TOXCAT and molecular dynamics simulation studies.MAVS self-association mediates antiviral innate immune signalingInteractions of platelet integrin alphaIIb and beta3 transmembrane domains in mammalian cell membranes and their role in integrin activationInteraction and conformational dynamics of membrane-spanning protein helices.Bax transmembrane domain interacts with prosurvival Bcl-2 proteins in biological membranes.Dimers of G-protein coupled receptors as versatile storage and response unitsIntegrin bi-directional signaling across the plasma membrane.
P2860
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P2860
Dimerization of the transmembrane domain of Integrin alphaIIb subunit in cell membranes
description
2004 nî lūn-bûn
@nan
2004 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Dimerization of the transmembrane domain of Integrin alphaIIb subunit in cell membranes
@ast
Dimerization of the transmembrane domain of Integrin alphaIIb subunit in cell membranes
@en
Dimerization of the transmembrane domain of Integrin alphaIIb subunit in cell membranes
@en-gb
Dimerization of the transmembrane domain of Integrin alphaIIb subunit in cell membranes
@nl
type
label
Dimerization of the transmembrane domain of Integrin alphaIIb subunit in cell membranes
@ast
Dimerization of the transmembrane domain of Integrin alphaIIb subunit in cell membranes
@en
Dimerization of the transmembrane domain of Integrin alphaIIb subunit in cell membranes
@en-gb
Dimerization of the transmembrane domain of Integrin alphaIIb subunit in cell membranes
@nl
prefLabel
Dimerization of the transmembrane domain of Integrin alphaIIb subunit in cell membranes
@ast
Dimerization of the transmembrane domain of Integrin alphaIIb subunit in cell membranes
@en
Dimerization of the transmembrane domain of Integrin alphaIIb subunit in cell membranes
@en-gb
Dimerization of the transmembrane domain of Integrin alphaIIb subunit in cell membranes
@nl
P2093
P2860
P921
P356
P1476
Dimerization of the transmembrane domain of Integrin alphaIIb subunit in cell membranes
@en
P2093
James D Lear
Joel S Bennett
Peter B Law
Roman Gorelik
P2860
P304
P356
10.1074/JBC.M314168200
P407
P577
2004-06-18T00:00:00Z