Identification of a (CUG)n triplet repeat RNA-binding protein and its expression in myotonic dystrophy - Test2 - elhamkhani - TriplyDB

Identification of a (CUG)n triplet repeat RNA-binding protein and its expression in myotonic dystrophy

Identification of a (CUG)n triplet repeat RNA-binding protein and its expression in myotonic dystrophy

http://www.wikidata.org/entity/Q24328773

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Genome analysis reveals interplay between 5'UTR introns and nuclear mRNA export for secretory and mitochondrial genes A family of human RNA-binding proteins related to the Drosophila Bruno translational regulator Recruitment of human muscleblind proteins to (CUG)(n) expansions associated with myotonic dystrophy The CELF family of RNA binding proteins is implicated in cell-specific and developmentally regulated alternative splicing Interaction of muscleblind, CUG-BP1 and hnRNP H proteins in DM1-associated aberrant IR splicing Competition of CUGBP1 and calreticulin for the regulation of p21 translation determines cell fate.CELF6, a member of the CELF family of RNA-binding proteins, regulates muscle-specific splicing enhancer-dependent alternative splicing Calreticulin interacts with C/EBPalpha and C/EBPbeta mRNAs and represses translation of C/EBP proteins RNPC1, an RNA-binding protein and a target of the p53 family, is required for maintaining the stability of the basal and stress-induced p21 transcript Epidermal growth factor receptor stimulation activates the RNA binding protein CUG-BP1 and increases expression of C/EBPbeta-LIP in mammary epithelial cells Failure of MBNL1-dependent post-natal splicing transitions in myotonic dystrophy EDEN and EDEN-BP, a cis element and an associated factor that mediate sequence-specific mRNA deadenylation in Xenopus embryos.CUG-BP binds to RNA substrates and recruits PARN deadenylase Molecular basis for impaired muscle differentiation in myotonic dystrophy Cytoplasmic polyadenylation in development and beyond In vivo co-localisation of MBNL protein with DMPK expanded-repeat transcripts Differentiation-induced colocalization of the KH-type splicing regulatory protein with polypyrimidine tract binding protein and the c-src pre-mRNA Expanded GGGGCC hexanucleotide repeat in noncoding region of C9ORF72 causes chromosome 9p-linked FTD and ALS The perinucleolar compartment Conserved GU-rich elements mediate mRNA decay by binding to CUG-binding protein 1 Altered phosphorylation and intracellular distribution of a (CUG)n triplet repeat RNA-binding protein in patients with myotonic dystrophy and in myotonin protein kinase knockout mice Elevation of RNA-binding protein CUGBP1 is an early event in an inducible heart-specific mouse model of myotonic dystrophy CUG-BP1/CELF1 requires UGU-rich sequences for high-affinity binding Defining early steps in mRNA transport: mutant mRNA in myotonic dystrophy type I is blocked at entry into SC-35 domains.HnRNP H inhibits nuclear export of mRNA containing expanded CUG repeats and a distal branch point sequence.The importance of CELF control: molecular and biological roles of the CUG-BP, Elav-like family of RNA-binding proteins Myotonic dystrophy: is a narrow focus obscuring the rest of the field?Converging mechanisms in ALS and FTD: disrupted RNA and protein homeostasis RNA-mediated neurodegeneration in fragile X-associated tremor/ataxia syndrome The unstable repeats--three evolving faces of neurological disease Triplet repeat-derived siRNAs enhance RNA-mediated toxicity in a Drosophila model for myotonic dystrophy Structural basis for the sequence-specific RNA-recognition mechanism of human CUG-BP1 RRM3 Structural Insights into RNA Recognition by the Alternate-Splicing Regulator CUG-Binding Protein 1 Identification of variants in MBNL1 in patients with a myotonic dystrophy-like phenotype RNA CUG repeats sequester CUGBP1 and alter protein levels and activity of CUGBP1 c-Jun ARE targets mRNA deadenylation by an EDEN-BP (embryo deadenylation element-binding protein)-dependent pathway Alternative splicing of myomesin 1 gene is aberrantly regulated in myotonic dystrophy type 1 MBNL1 is the primary determinant of focus formation and aberrant insulin receptor splicing in DM1 The CUGBP2 splicing factor regulates an ensemble of branchpoints from perimeter binding sites with implications for autoregulation Coordinate repression of a trio of neuron-specific splicing events by the splicing regulator PTB

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Identification of a (CUG)n triplet repeat RNA-binding protein and its expression in myotonic dystrophy

http://www.wikidata.org/entity/Q24328773

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1996 nî lūn-bûn

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1996 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

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1996 թվականի նոյեմբերին հրատարակված գիտական հոդված

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1996年の論文

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1996年論文

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1996年論文

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Identification of a (CUG)n tri ...... pression in myotonic dystrophy

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Identification of a (CUG)n tri ...... pression in myotonic dystrophy

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Identification of a (CUG)n tri ...... pression in myotonic dystrophy

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Nucleic Acids Research

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Identification of a (CUG)n tri ...... pression in myotonic dystrophy

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C T Caskey

http://www.w3.org/2001/XMLSchema#string

D R DeVore

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J W Miller

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K V Datar

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L Lin

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L T Timchenko

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N A Timchenko

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R Roberts

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P2860

hnRNP I, the polypyrimidine tract-binding protein: distinct nuclear localization and association with hnRNAs

A novel heterogeneous nuclear RNP protein with a unique distribution on nascent transcripts

The structure of trp RNA-binding attenuation protein

NAB2: a yeast nuclear polyadenylated RNA-binding protein essential for cell viability.

Characterization of nuclear polyadenylated RNA-binding proteins in Saccharomyces cerevisiae.

The human hnRNP M proteins: identification of a methionine/arginine-rich repeat motif in ribonucleoproteins

Myotonic dystrophy mutation: an unstable CTG repeat in the 3' untranslated region of the gene

Novel proteins with binding specificity for DNA CTG repeats and RNA CUG repeats: implications for myotonic dystrophy

hnRNP proteins and the biogenesis of mRNA

Shuttling of pre-mRNA binding proteins between nucleus and cytoplasm

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4407-4414

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scholarly article

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1104643

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10.1093/NAR/24.22.4407

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22

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24

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Maurice S. Swanson

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1996-11-01T00:00:00Z

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14258071

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8948631

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mRNA processing

CUGBP Elav-like family member 1

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146274

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