Vaccinia-related kinase 1 (VRK1) is an upstream nucleosomal kinase required for the assembly of 53BP1 foci in response to ionizing radiation-induced DNA damage

Vaccinia-related kinase 1 (VRK1) is an upstream nucleosomal kinase required for the assembly of 53BP1 foci in response to ionizing radiation-induced DNA damage

Item
http://www.wikidata.org/entity/Q24336079
Human VRK2 modulates apoptosis by interaction with Bcl-xL and regulation of BAX gene expressionVRK1 interacts with p53 forming a basal complex that is activated by UV-induced DNA damageVRK1 chromatin kinase phosphorylates H2AX and is required for foci formation induced by DNA damageLuteolin suppresses cancer cell proliferation by targeting vaccinia-related kinase 1Vaccinia-related kinase 1 (VRK1) confers resistance to DNA-damaging agents in human breast cancer by affecting DNA damage responseVRK2 identifies a subgroup of primary high-grade astrocytomas with a better prognosisVRK1 regulates Cajal body dynamics and protects coilin from proteasomal degradation in cell cyclePredictive value of vrk 1 and 2 for rectal adenocarcinoma response to neoadjuvant chemoradiation therapy: a retrospective observational cohort studyUrsolic acid exerts anti-cancer activity by suppressing vaccinia-related kinase 1-mediated damage repair in lung cancer cells.Expression of vaccinia-related kinase 1 (VRK1) accelerates cell proliferation but overcomes cell adhesion mediated drug resistance (CAM-DR) in multiple myeloma.VRK1 promotes cisplatin resistance by up-regulating c-MYC via c-Jun activation and serves as a therapeutic target in esophageal squamous cell carcinoma.Oncogenic Sox2 regulates and cooperates with VRK1 in cell cycle progression and differentiationVRK1 and AURKB form a complex that cross inhibit their kinase activity and the phosphorylation of histone H3 in the progression of mitosis.Implication of the VRK1 chromatin kinase in the signaling responses to DNA damage: a therapeutic target?Sensitivity of the kinase activity of human vaccinia-related kinase proteins to toxic metals.Functional characterization of lysosomal interaction of Akt with VRK2.Overexpression of the VRK1 kinase, which is associated with breast cancer, induces a mesenchymal to epithelial transition in mammary epithelial cells
P2860

Vaccinia-related kinase 1 (VRK1) is an upstream nucleosomal kinase required for the assembly of 53BP1 foci in response to ionizing radiation-induced DNA damage

Item
http://www.wikidata.org/entity/Q24336079
description
2012 nî lūn-bûn
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2012 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Vaccinia-related kinase 1 (VRK ...... g radiation-induced DNA damage
@ast
Vaccinia-related kinase 1 (VRK ...... g radiation-induced DNA damage
@en
Vaccinia-related kinase 1 (VRK ...... g radiation-induced DNA damage
@en-gb
Vaccinia-related kinase 1 (VRK ...... g radiation-induced DNA damage
@nl
type
label
Vaccinia-related kinase 1 (VRK ...... g radiation-induced DNA damage
@ast
Vaccinia-related kinase 1 (VRK ...... g radiation-induced DNA damage
@en
Vaccinia-related kinase 1 (VRK ...... g radiation-induced DNA damage
@en-gb
Vaccinia-related kinase 1 (VRK ...... g radiation-induced DNA damage
@nl
prefLabel
Vaccinia-related kinase 1 (VRK ...... g radiation-induced DNA damage
@ast
Vaccinia-related kinase 1 (VRK ...... g radiation-induced DNA damage
@en
Vaccinia-related kinase 1 (VRK ...... g radiation-induced DNA damage
@en-gb
Vaccinia-related kinase 1 (VRK ...... g radiation-induced DNA damage
@nl
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P1476
P2093
P2860
P304
P31
P3181
P356
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P433
P478
P50
P577
P698
P921
P932
P3181
P356
P1433
P1476
Vaccinia-related kinase 1 (VRK ...... g radiation-induced DNA damage
@en
P2093
P2860
P304
P31
P3181
P356
P407
P433
P478
P50
P577
P698
P921
P932