Elucidation of Rab27 recruitment by its effectors: structure of Rab27a bound to Exophilin4/Slp2-a
about
A structural basis for Lowe syndrome caused by mutations in the Rab-binding domain of OCRL1Regulation of vesicular trafficking and leukocyte function by Rab27 GTPases and their effectorsStructural and Functional Analysis of the Globular Head Domain of p115 Provides Insight into Membrane TetheringStructural basis for Rab GTPase recognition and endosome tethering by the C2H2 zinc finger of Early Endosomal Autoantigen 1 (EEA1)Identification of novel rab27a/melanophilin blockers by pharmacophore-based virtual screening.Patients with Griscelli syndrome and normal pigmentation identify RAB27A mutations that selectively disrupt MUNC13-4 binding.Rab27 effector Slp2-a transports the apical signaling molecule podocalyxin to the apical surface of MDCK II cells and regulates claudin-2 expression.Synaptotagmin-like proteins control the formation of a single apical membrane domain in epithelial cellsRab27a targeting to melanosomes requires nucleotide exchange but not effector bindingA Heterozygous RAB27A Mutation Associated with Delayed Cytolytic Granule Polarization and Hemophagocytic Lymphohistiocytosis.The charge-dipole pocket: a defining feature of signaling pathway GTPase on/off switches.Structural mechanisms for regulation of membrane traffic by rab GTPasesRab27 effectors, pleiotropic regulators in secretory pathways.Regulatory mechanisms of RANKL presentation to osteoclast precursors.Structures of Ras superfamily effector complexes: What have we learnt in two decades?Multivalency in Rab effector interactions.Identification of Neutrophil Exocytosis Inhibitors (Nexinhibs), Small Molecule Inhibitors of Neutrophil Exocytosis and Inflammation: DRUGGABILITY OF THE SMALL GTPase Rab27a.Rab GTPases and their interacting protein partners: Structural insights into Rab functional diversity.bMERB domains are bivalent Rab8 family effectors evolved by gene duplicationRab27a negatively regulates phagocytosis by prolongation of the actin-coating stage around phagosomes.
P2860
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P2860
Elucidation of Rab27 recruitment by its effectors: structure of Rab27a bound to Exophilin4/Slp2-a
description
2008 nî lūn-bûn
@nan
2008 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Elucidation of Rab27 recruitme ...... 27a bound to Exophilin4/Slp2-a
@ast
Elucidation of Rab27 recruitme ...... 27a bound to Exophilin4/Slp2-a
@en
Elucidation of Rab27 recruitme ...... 27a bound to Exophilin4/Slp2-a
@en-gb
Elucidation of Rab27 recruitme ...... 27a bound to Exophilin4/Slp2-a
@nl
type
label
Elucidation of Rab27 recruitme ...... 27a bound to Exophilin4/Slp2-a
@ast
Elucidation of Rab27 recruitme ...... 27a bound to Exophilin4/Slp2-a
@en
Elucidation of Rab27 recruitme ...... 27a bound to Exophilin4/Slp2-a
@en-gb
Elucidation of Rab27 recruitme ...... 27a bound to Exophilin4/Slp2-a
@nl
prefLabel
Elucidation of Rab27 recruitme ...... 27a bound to Exophilin4/Slp2-a
@ast
Elucidation of Rab27 recruitme ...... 27a bound to Exophilin4/Slp2-a
@en
Elucidation of Rab27 recruitme ...... 27a bound to Exophilin4/Slp2-a
@en-gb
Elucidation of Rab27 recruitme ...... 27a bound to Exophilin4/Slp2-a
@nl
P2093
P3181
P1433
P1476
Elucidation of Rab27 recruitme ...... 27a bound to Exophilin4/Slp2-a
@en
P2093
Kentaro Ihara
Leonard M G Chavas
Masato Kawasaki
Ryuichi Kato
Seiji Torii
Tamami Uejima
Tetsuro Izumi
P304
P3181
P356
10.1016/J.STR.2008.07.015
P407
P577
2008-10-08T00:00:00Z