Proteomic analysis of cap-dependent translation identifies LARP1 as a key regulator of 5'TOP mRNA translation
about
Regulation of global and specific mRNA translation by the mTOR signaling pathwayThe La-Related Proteins, a Family with Connections to CancerThe expanding role of mTOR in cancer cell growth and proliferationStructure of the eukaryotic translation initiation factor eIF4E in complex with 4EGI-1 reveals an allosteric mechanism for dissociating eIF4GThe La-related protein 1-specific domain repurposes HEAT-like repeats to directly bind a 5'TOP sequenceLa-related Protein 1 (LARP1) Represses Terminal Oligopyrimidine (TOP) mRNA Translation Downstream of mTOR Complex 1 (mTORC1)Modulation of nonsense mediated decay by rapamycinAuxin Signaling in Regulation of Plant Translation ReinitiationNew frontiers in translational control of the cancer genomePoly(A)-binding proteins are required for diverse biological processes in metazoans.Cellular differences in protein synthesis regulate tissue homeostasis.Growing knowledge of the mTOR signaling network.The yeast La related protein Slf1p is a key activator of translation during the oxidative stress response.Targeting the eIF4F translation initiation complex: a critical nexus for cancer developmentReassessment of the role of TSC, mTORC1 and microRNAs in amino acids-meditated translational control of TOP mRNAs.LARP1 post-transcriptionally regulates mTOR and contributes to cancer progressionMechanism of cytoplasmic mRNA translation.Assessment of mTOR-Dependent Translational Regulation of Interferon Stimulated GenesA Multi-Marker Genetic Association Test Based on the Rasch Model Applied to Alzheimer's Disease.Profiling of the fetal and adult rat liver transcriptome and translatome reveals discordant regulation by the mechanistic target of rapamycin (mTOR)nanoCAGE reveals 5' UTR features that define specific modes of translation of functionally related MTOR-sensitive mRNAsEpidermal Growth Factor Receptor-Dependent Mutual Amplification between Netrin-1 and the Hepatitis C Virus.Long non-coding RNA growth arrest-specific transcript 5 in tumor biology.mTOR coordinates protein synthesis, mitochondrial activity and proliferation.The RNA-binding protein LARP1 is a post-transcriptional regulator of survival and tumorigenesis in ovarian cancer.Combinatorial targeting of nuclear export and translation of RNA inhibits aggressive B-cell lymphomas.A liaison between mTOR signaling, ribosome biogenesis and cancermTORC1 and CK2 coordinate ternary and eIF4F complex assembly.The mitochondrial outer membrane protein MDI promotes local protein synthesis and mtDNA replicationToward the mechanism of eIF4F-mediated ribosomal attachment to mammalian capped mRNAsOverexpression of LARP1 predicts poor prognosis of colorectal cancer and is expected to be a potential therapeutic target.Translational control of immune responses: from transcripts to translatomes.A nexus for cellular homeostasis: the interplay between metabolic and signal transduction pathways.The role of LARP1 in translation and beyond.Global Phosphoproteomic Analysis of Insulin/Akt/mTORC1/S6K Signaling in Rat Hepatocytes.La-related protein 1 (LARP1) binds the mRNA cap, blocking eIF4F assembly on TOP mRNAsMolecular mechanisms of mTOR regulation by stressmTORC1 signaling and the metabolic control of cell growth.LARP4B is an AU-rich sequence associated factor that promotes mRNA accumulation and translation.LARP1 functions as a molecular switch for mTORC1-mediated translation of an essential class of mRNAs.
P2860
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P2860
Proteomic analysis of cap-dependent translation identifies LARP1 as a key regulator of 5'TOP mRNA translation
description
2014 nî lūn-bûn
@nan
2014 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Proteomic analysis of cap-depe ...... ator of 5'TOP mRNA translation
@ast
Proteomic analysis of cap-depe ...... ator of 5'TOP mRNA translation
@en
Proteomic analysis of cap-depe ...... ator of 5'TOP mRNA translation
@en-gb
Proteomic analysis of cap-depe ...... ator of 5'TOP mRNA translation
@nl
type
label
Proteomic analysis of cap-depe ...... ator of 5'TOP mRNA translation
@ast
Proteomic analysis of cap-depe ...... ator of 5'TOP mRNA translation
@en
Proteomic analysis of cap-depe ...... ator of 5'TOP mRNA translation
@en-gb
Proteomic analysis of cap-depe ...... ator of 5'TOP mRNA translation
@nl
prefLabel
Proteomic analysis of cap-depe ...... ator of 5'TOP mRNA translation
@ast
Proteomic analysis of cap-depe ...... ator of 5'TOP mRNA translation
@en
Proteomic analysis of cap-depe ...... ator of 5'TOP mRNA translation
@en-gb
Proteomic analysis of cap-depe ...... ator of 5'TOP mRNA translation
@nl
P2093
P2860
P50
P3181
P356
P1433
P1476
Proteomic analysis of cap-depe ...... ator of 5'TOP mRNA translation
@en
P2093
Genevieve Lavoie
Joseph Tcherkezian
Yves Romeo
P2860
P304
P3181
P356
10.1101/GAD.231407.113
P407
P577
2014-02-01T00:00:00Z